- Conditions
- Colorectal Cancer Control and Prevention
- Interventions
- single GPT generated message, AI Chatbot, Expert-Written Patient Materials
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 915 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 27
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Alcohol Use Disorder
- Interventions
- Large language model-based chatbot brief alcohol intervention session
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 29 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- AI (Artificial Intelligence), Large Language Model, Generative Artificial Intelligence
- Interventions
- AI clinical reference tool
- Other
- Lead sponsor
- Cambridge Health Alliance
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
- Interventions
- Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
- Other
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees, Participants Should Not be Employed in the Healthcare Field, Participants Should Reside in the United States and be a University of California, San Francisco Health Patient, Participants Should Possess a Smartphone With an Active Data Plan or Access to Wi-Fi
- Interventions
- HeartBot II Program, Waitlist Control
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 25 Years and older · Female only
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Ophthalmic Disease, Artifical Intelligence, Large Language Model
- Interventions
- AI-Generated Plain Language Summaries
- Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 460 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Large Language Models
- Interventions
- OpenEvidence, GPT-4
- Other
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • The Bronx, New York
- Conditions
- Gastrointestinal Cancer, Gastrointestinal Tumor, Gastrointestinal Tumor Surgery, Gastrointestinal Surgery
- Interventions
- Voice-Assisted Remote Symptom Monitoring System (VARSMS)
- Other
- Lead sponsor
- Medstar Health Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 281 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Omaha, Nebraska
- Conditions
- HPV Vaccination Intent
- Interventions
- Default-style LLM chatbot, Conversational-style LLM chatbot, Public health informational materials
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 930 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Heart Failure
- Interventions
- LLM-GDMT Clinical Decision Support Tool
- Device
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Clinical Decision-making
- Interventions
- GPT-4
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- Not listed
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Communication, Artificial Intelligence (AI), Artificial Intelligence Technology, Interdisciplinary Communication
- Interventions
- Large Language Model-generated Plain Language Summary of Ophthalmology notes
- Other
- Lead sponsor
- John J Chen
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 851 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Large Language Model
- Interventions
- CURE
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- High-Risk Multidisciplinary Care, Clinical Decision Support, Artificial Intelligence-Assisted Care, Telemedicine
- Interventions
- Gemini 3.1 Pro with Safety Prompt, ANCHOR Clinical AI Verification Layer (with Gemini 3.1 Pro)
- Behavioral
- Lead sponsor
- Waymark
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Glaucoma, Eye Disorders, Visual Fields, Visual Field Tests
- Interventions
- LLM-based Education
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Gastrointestinal Neoplasm Malignant
- Interventions
- Clinician-Directed Treatment Plan, ChatGPT-Assisted Treatment Plan
- Other
- Lead sponsor
- Chinese Academy of Sciences
- Government
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Duarte, California
- Conditions
- Diagnosis
- Interventions
- GPT-4
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- Not listed
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Pathologic Processes, Disease
- Interventions
- Immediate access to customized version of GPT-4, Access to customized version of GPT-4 following use of conventional resources
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- Not listed
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Major Depressive Disorder (MDD)
- Interventions
- Conversational AI system vs Usual Care
- Other
- Lead sponsor
- George Mason University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Fairfax, Virginia
- Conditions
- Electronic Medical Record, Transitions of Care, Physician Workflow, Artificial Intelligence (AI), Large Language Model
- Interventions
- LLM tool to draft handoff
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience, Cataract Surgery, Intraocular Lens
- Interventions
- LLM-based Education
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Hypertrophic Cardiomyopathy (HCM), Cardiomyopathy, Genetic Disease, Cardiology
- Interventions
- Large Language Model
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure, Acute Kidney Injury, Delirium Confusional State, Shock
- Interventions
- Point-of-care large language model decision support (ChatGPT-5)
- Other
- Lead sponsor
- MetroWest Artificial Intelligence Research Workgroup
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Framingham, Massachusetts
- Conditions
- Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia), Reminiscence Therapy
- Interventions
- Smart Virtual Reminiscence Therapy, Music Therapy
- Device · Other
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana