- Conditions
- Major Depression, Late Life Depression (LLD)
- Interventions
- Not listed
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2027
- U.S. locations
- 2
- States / cities
- San Francisco, California • Pittsburgh, Pennsylvania
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- Conditions
- Late Life Depression (LLD)
- Interventions
- High-intensity (6 mA) transcranial direct current stimulation (tDCS)
- Device
- Lead sponsor
- Andre Russowsky Brunoni
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Treatment Resistant Depression (TRD), Late Life Depression (LLD), Depression / Major Depressive Disorder
- Interventions
- Lumateperone, Placebo
- Drug
- Lead sponsor
- Eric Lenze
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Tucson, Arizona • St Louis, Missouri