- Conditions
- Necrotizing Enterocolitis, Sepsis
- Interventions
- Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement
- Behavioral
- Lead sponsor
- National Center for Research Resources (NCRR)
- NIH
- Eligibility
- 0 Years to 96 Hours
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1997
- U.S. locations
- 1
- States / cities
- Houston, Texas
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Showing 1–9
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- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis, Motor Skills Disorders
- Interventions
- delayed cord clamping
- Procedure
- Lead sponsor
- University of Rhode Island
- Other
- Eligibility
- Female only
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Neonatal Early-onset Sepsis, Neonatal Late-onset Sepsis
- Interventions
- Intervention is to stop antibiotics at 24h .
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 1 Hour to 5 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Late-onset Sepsis
- Interventions
- Ceftaroline Fosamil, Ampicillin, Aminoglycoside
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 7 Days to 59 Days
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
- Interventions
- oropharyngeal mother's milk, oropharyngeal sterile water
- Other
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 1 Day to 4 Days
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 5
- States / cities
- Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more
- Conditions
- Antibiotic Stewardship, Neonatal Sepsis, Late-Onset, Vancomycin
- Interventions
- External Facilitation
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 13
- States / cities
- Modesto, California • Oakland, California • Roseville, California + 9 more
- Conditions
- Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
- Interventions
- Ampicillin, Gentamycin, Normal saline
- Drug
- Lead sponsor
- Michael Morowitz
- Other
- Eligibility
- Up to 4 Hours
- Enrollment
- 359 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 14
- States / cities
- Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
- Conditions
- Neonatal Sepsis
- Interventions
- Ceftobiprole medocaril
- Drug
- Lead sponsor
- Basilea Pharmaceutica
- Industry
- Eligibility
- 3 Days to 3 Months
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 2
- States / cities
- Evanston, Illinois • Morgantown, West Virginia
- Conditions
- Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
- Interventions
- Dopamine, Norepinephrine
- Drug
- Lead sponsor
- Mount Sinai Hospital, Canada
- Other
- Eligibility
- 21 Weeks to 32 Weeks
- Enrollment
- 550 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Dayton, Ohio • San Antonio, Texas