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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Late Preterm Infant Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)

NCT03979313
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
MEDI8897, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
0 Years to 1 Year
Enrollment
3,012 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
66
States / cities
Birmingham, Alabama • Fort Defiance, Arizona • Fayetteville, Arkansas + 59 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jul 23, 2026, 8:58 PM EDT
Recruiting Not applicable Interventional

Vancomycin Reduction Practices (VRP) in the NICU

NCT06772675
View directory record Official record
Conditions
Antibiotic Stewardship, Neonatal Sepsis, Late-Onset, Vancomycin
Interventions
External Facilitation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
13
States / cities
Modesto, California • Oakland, California • Roseville, California + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeted Nutrition for Moderate to Late Preterm Infants

NCT05515614
View directory record Official record
Conditions
Premature Birth, Breastmilk Collection, Postnatal Growth Restriction
Interventions
Targeted Fortification, Enfamil Liquid Human Milk Fortifier
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
Not listed
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Phase 4 Interventional

NICU Antibiotics and Outcomes Trial

NCT03997266
View directory record Official record
Conditions
Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions
Ampicillin, Gentamycin, Normal saline
Drug
Lead sponsor
Michael Morowitz
Other
Eligibility
Up to 4 Hours
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
14
States / cities
Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Phase 3 Interventional Results available

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide

NCT00569530
View directory record Official record
Conditions
Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
Interventions
Infasurf (ONY Inc.), Sham
Drug
Lead sponsor
Roberta Ballard
Other
Eligibility
7 Days to 14 Days
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
9
States / cities
Berkeley, California • Oakland, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional Results available

Feeding and Wellness Among Late Preterm Infants

NCT00470717
View directory record Official record
Conditions
Late Preterm Infant
Interventions
Weekly telephone call
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Jul 23, 2026, 8:58 PM EDT
Completed No phase listed Observational

Neurophysiologic Maturation Index for Late Preterm Infants

NCT02156817
View directory record Official record
Conditions
Neurophysiologic Maturation
Interventions
Amplitude integrated electroencephalogram, Cardiorespiratory signal acquisition
Other
Lead sponsor
Brown University
Other
Eligibility
1 Day to 4 Days
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Jul 23, 2026, 8:58 PM EDT
Terminated Not applicable Interventional Results available

Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure

NCT00833365
View directory record Official record
Conditions
Patent Ductus Arteriosus, Prematurity
Interventions
Ibuprofen
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 96 Hours
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 3, 2016 · Synced Jul 23, 2026, 8:58 PM EDT
Enrolling by invitation Not applicable Interventional

Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

NCT07176117
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Surfactant
Interventions
Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA), Continuous Positive Airway Pressure (CPAP)
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
33 Weeks to 38 Weeks
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
3
States / cities
Chula Vista, California • La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants

NCT00875758
View directory record Official record
Conditions
Intraventricular Hemorrhage, Hydrocephalus
Interventions
Removal of CSF through ventricular access device, Removal of CSF through a ventricular access device
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 34 Weeks
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Phase 2Phase 3 Interventional

Dextrose Gel Does Not Prevent Neonatal Hypoglycemia

NCT02523222
View directory record Official record
Conditions
Hypoglycemia, Infant, Small for Gestational Age, Premature Birth of Newborn, Fetal Macrosomia, Intrauterine Growth Restriction, Complication of Prematurity, Neonatal Hypoglycemia
Interventions
40% Dextrose gel
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Hours to 1 Hour
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants

NCT00113191
View directory record Official record
Conditions
Nosocomial Infections, Sepsis, Staphylococcal Infections, Candidemia
Interventions
Veronate
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
3 Days to 5 Days
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
85
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 71 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional Results available

Fluid Management in Transient Tachypnea of the Newborn

NCT01225029
View directory record Official record
Conditions
Transient Tachypnea of the Newborn
Interventions
Amount of total fluids
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)

NCT02116699
View directory record Official record
Conditions
Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
Interventions
oropharyngeal mother's milk, oropharyngeal sterile water
Other
Lead sponsor
Endeavor Health
Other
Eligibility
1 Day to 4 Days
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
5
States / cities
Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Jul 23, 2026, 8:58 PM EDT
Completed No phase listed Observational

Hypotension in Neonates

NCT00882284
View directory record Official record
Conditions
Infant, Newborn, Hypotension, Blood Pressure
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 72 Hours
Enrollment
820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Donor Breast Milk and Breastfeeding Rates

NCT04572581
View directory record Official record
Conditions
Breastfeeding, Exclusive, Breastfeeding
Interventions
Donor Breast Milk
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Up to 3 Days
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Jul 23, 2026, 8:58 PM EDT
Recruiting No phase listed Observational

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

NCT05347238
View directory record Official record
Conditions
Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
Interventions
Dopamine, Norepinephrine
Drug
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
21 Weeks to 32 Weeks
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Phoenix, Arizona • Dayton, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 23, 2026, 8:58 PM EDT
Completed No phase listed Observational

Neurophysiological Maturation Correlate With Clinical Milestones

NCT03722901
View directory record Official record
Conditions
Neurophysiologic Maturation
Interventions
Not listed
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Up to 4 Days
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic Continuous Positive Airway Pressure (CPAP) in Delivery Room, in the Prevention of Transient Tachypnea of Newborn (TTN): A Randomized Controlled Trial

NCT01082900
View directory record Official record
Conditions
Transient Tachypnea
Interventions
Prophylactic CPAP Administration
Other
Lead sponsor
New York Hospital Queens
Other
Eligibility
2 Minutes to 30 Minutes
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Jul 23, 2026, 8:58 PM EDT
Suspended Not applicable Interventional

The Milk, Growth and Microbiota Study

NCT03220282
View directory record Official record
Conditions
Preterm Infant, Growth Delay, Microbial Colonization, Breastfeeding, Breast Milk Substitute Intolerance
Interventions
Donor milk, Preterm infant formula
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Hour to 96 Hours
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 23, 2026, 8:58 PM EDT
Completed Phase 3 Interventional Results available

Hydrocortisone for Term Hypotension

NCT01954056
View directory record Official record
Conditions
Infant, Newborn, Diseases, Cardiovascular Insufficiency
Interventions
Hydrocortisone, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
34 Weeks and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
18
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2021 · Synced Jul 23, 2026, 8:58 PM EDT
Completed No phase listed Observational

Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants

NCT00795990
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 3 Months
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Jul 23, 2026, 8:58 PM EDT
Active, not recruiting Not applicable Interventional

Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension

NCT04938167
View directory record Official record
Conditions
Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure
Interventions
95% - 99% SpO2 target
Other
Lead sponsor
University of California, Davis
Other
Eligibility
0 Days to 28 Days
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 23, 2026, 8:58 PM EDT
Not listed No phase listed Observational

Unbound Bilirubin Levels in Healthy Term and Late Preterm Infants

NCT03237715
View directory record Official record
Conditions
Neonatal Jaundice
Interventions
Assessment of unbound bilirubin levels
Other
Lead sponsor
Rutgers University
Other
Eligibility
6 Hours to 7 Days
Enrollment
180 participants
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Jul 23, 2026, 8:58 PM EDT