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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Lens Disease Clear all
Completed Phase 3 Interventional Results available

Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.

NCT01475643
View directory record Official record
Conditions
Cataract
Interventions
Loteprednol etabonate, Prednisolones acetate
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
Up to 11 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery

NCT01847638
View directory record Official record
Conditions
Cataract, Retinal Edema, Inflammation
Interventions
Prolensa (bromfenac 0.07%), Ilevro (nepafenac 0.3%)
Drug
Lead sponsor
Melissa Toyos
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Jul 22, 2026, 8:03 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects

NCT06922084
View directory record Official record
Conditions
Cataract
Interventions
Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
Device · Drug
Lead sponsor
Berkeley Eye Center
Other
Eligibility
40 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Plymouth Meeting, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment

NCT03430921
View directory record Official record
Conditions
Scarring, Acne
Interventions
Enlighten™ Laser and a MLA Attachment
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3

NCT04942925
View directory record Official record
Conditions
Myopia, Ametropia
Interventions
Verofilcon A contact lenses, Kalifilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
4
States / cities
Maitland, Florida • Orlando, Florida • Eden Prairie, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Reusable Soft Contact Lenses

NCT06119191
View directory record Official record
Conditions
Myopia
Interventions
Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Berkeley, California • Bloomington, Indiana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Phase 3 Interventional

Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in the Treatment of Allergic Conjunctivitis

NCT00445874
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
Ketotifen with a Contact Lens (no generic name)
Drug
Lead sponsor
Vistakon Pharmaceuticals
Industry
Eligibility
8 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
7
States / cities
Phoenix, Arizona • Irvine, California • North Andover, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation"

NCT04781335
View directory record Official record
Conditions
Cataract
Interventions
Dexycu, Standard of Care post operative eye drops (steroid, antibiotic, NSAID)
Drug
Lead sponsor
The Eye Institute of West Florida
Other
Eligibility
40 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Largo, Florida
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

NCT05338333
View directory record Official record
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Phase 3 Interventional Results available

A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma

NCT00323284
View directory record Official record
Conditions
Open-Angle Glaucoma
Interventions
iStent plus Cataract Surgery, Cataract surgery only
Device · Procedure
Lead sponsor
Glaukos Corporation
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
31
States / cities
Beverly Hills, California • Petaluma, California • Sacramento, California + 27 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Vistakon Investigational Contact Lenses Worn for Daily Wear

NCT00717249
View directory record Official record
Conditions
Myopia
Interventions
galyifilcon A control lens, galyfilcon A with a silver additive
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
20
States / cities
Fresno, California • Mission Viejo, California • Louisville, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Phase 3 Interventional Results available

Age-Related Eye Disease Study 2 (AREDS2)

NCT00345176
View directory record Official record
Conditions
Age-related Macular Degeneration, Cataract
Interventions
Lutein/zeaxanthin, DHA/EPA, Lutein/zeaxanthin and DHA/EPA
Dietary Supplement · Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
50 Years to 85 Years
Enrollment
4,203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
91
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Beverly Hills, California + 72 more
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Comparison of Three Soft Bifocal Contact Lenses

NCT00808340
View directory record Official record
Conditions
Presbyopia
Interventions
balafilcon A, senofilcon A production, senofilcon A test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
35 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Investigation of Healon EndoCoat Ophthalmic Viscosurgical Device (OVD)

NCT05575063
View directory record Official record
Conditions
Cataracts
Interventions
Investigational Healon Endocoat, Control Healon EndoCoat
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Bakersfield, California • Long Beach, California • Cranberry Township, Pennsylvania + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional

Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery

NCT02561104
View directory record Official record
Conditions
Incipient Cataract, Senile Nuclear Sclerosis
Interventions
Laser-assisted cataract surgery., Traditional manual phacoemulsification
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 99 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

NCT05985304
View directory record Official record
Conditions
Cataract, Corneal Astigmatism
Interventions
RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Rayner Intraocular Lenses Limited
Industry
Eligibility
22 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
9
States / cities
Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 22, 2026, 8:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
View directory record Official record
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Jul 22, 2026, 8:03 PM EDT
Recruiting No phase listed Observational

Effective Phaco Time and Endothelial Cell Loss When Using Veritas

NCT07176416
View directory record Official record
Conditions
Cataract
Interventions
Veritas Vision System
Device
Lead sponsor
Aloha Vision Consultants
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
‘Aiea, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 22, 2026, 8:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Prospective Trial of the Intelon BOSS(TM) System

NCT04969406
View directory record Official record
Conditions
Cornea, Lens Diseases
Interventions
Brillouin Spectroscopy via BOSS System
Other
Lead sponsor
Intelon Optics, Inc
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Jul 22, 2026, 8:03 PM EDT
Active, not recruiting Not applicable Interventional

Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear

NCT06009458
View directory record Official record
Conditions
Myopia
Interventions
Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
7 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Mission Viejo, California • Oakland, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jul 22, 2026, 8:03 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spectacle Lens Visual Acuity Assessments Study

NCT05650190
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
9 Years to 14 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 8:03 PM EDT
Terminated Not applicable Interventional Results available

Cataract Refractive Suite Study

NCT02974140
View directory record Official record
Conditions
Cataracts
Interventions
Cataract Refractive Suite (CRS), Standard manual technique
Device · Procedure
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
22 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
Panama City, Florida • Stillwater, Minnesota • Hurst, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Jul 22, 2026, 8:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

NCT03585790
View directory record Official record
Conditions
Asthenopia, Myopia
Interventions
Contact lens with Multifocal Optics, Contact lens with Single Vision Optics
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Jul 22, 2026, 8:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study

NCT04130490
View directory record Official record
Conditions
Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery, IOL
Interventions
ANTERION
Device
Lead sponsor
Heidelberg Engineering GmbH
Industry
Eligibility
22 Years and older
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Jul 22, 2026, 8:03 PM EDT