- Conditions
- Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
- Interventions
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
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Showing 1–24
of 229
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
- Conditions
- Osteoarthritis, Tendinitis, Sports Injury, Degenerative Disc Disease, Degenerative Arthritis, Ligament Injury, Neuropathy, Pelvic Pain
- Interventions
- Umbilical Allograft
- Other
- Lead sponsor
- R3 Stem Cell
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2030
- U.S. locations
- 1
- States / cities
- Encino, California
- Conditions
- ACL Tear
- Interventions
- Mental Skills Coaching
- Behavioral
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 8 Years to 25 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Waltham, Massachusetts
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
- Device · Other
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 13 Years to 50 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Fairfax, Virginia
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Focused Shockwave, Sham Focused Shockwave
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- ACL Tear
- Interventions
- Safe Return to Play Following ACL Reconstruction Checklist
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 15 Years to 35 Years
- Enrollment
- 222 participants
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- ACL, ACL Injury
- Interventions
- 3D printed knee extender device, Standard Prehabilitation Education
- Device · Other
- Lead sponsor
- Sanford Health
- Other
- Eligibility
- 14 Years to 60 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 2
- States / cities
- Fargo, North Dakota • Sioux Falls, South Dakota
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- BioCleanse Tibialis tendon
- Other
- Lead sponsor
- RTI Surgical
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
- Interventions
- Unbroken Comeback
- Other
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 15 Years to 25 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Fairfax, Virginia
- Conditions
- Knee Injury
- Interventions
- Anakinra
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Bankart Lesion, Acetabular Labrum Tear, SLAP Lesion, Acromioclavicular Sprain, Capsular Shift/Capsulolabral Reconstruction, Deltoid Repair, Rotator Cuff Repair, Bicep Tendinitis, Extra-capsular Repair, Medial Collateral Ligament, Lateal Collateral Ligament, Posterior Oblique Ligament, IBT, Vastus Medialis, Obliquus Advancement, Joint Capsule Closure
- Interventions
- The Q-Fix™ All-Suture Anchor
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 13 Years and older
- Enrollment
- 294 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 5
- States / cities
- Washington D.C., District of Columbia • Chicago, Illinois • New Orleans, Louisiana + 2 more
- Conditions
- Injury of Anterior Cruciate Ligament
- Interventions
- bupivacaine, continuous perineural infusion catheter
- Drug · Device
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Interventions
- Tranexamic Acid, Placebo
- Drug
- Lead sponsor
- Dave Bernholt
- Other
- Eligibility
- 14 Years to 25 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 6
- States / cities
- Skokie, Illinois • St Louis, Missouri • Durham, North Carolina + 3 more
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 40 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL, Anterior Cruciate Ligament Injuries
- Interventions
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
- Interventions
- dispense of study drug, Ketorolac
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 15 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- Coral Springs, Florida • Garfield, Ohio • Strongsville, Ohio
- Conditions
- Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
- Interventions
- Visuomotor Therapy, Passive Motion
- Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Interventions
- Exparel
- Drug
- Lead sponsor
- Texas Scottish Rite Hospital for Children
- Other
- Eligibility
- 13 Years to 21 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
- Interventions
- ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique
- Procedure
- Lead sponsor
- Marshall University
- Other
- Eligibility
- 14 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Huntington, West Virginia
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Fertilized ACL
- Procedure
- Lead sponsor
- Marshall University
- Other
- Eligibility
- 14 Years to 26 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Huntington, West Virginia
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
- Interventions
- ACL Repair with MIACH Scaffold, Standard ACL Reconstruction
- Device · Procedure
- Lead sponsor
- Miach Orthopaedics
- Industry
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Rupture of Anterior Cruciate Ligament
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 12 Years to 65 Years
- Enrollment
- 1,234 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2030
- U.S. locations
- 47
- States / cities
- La Jolla, California • Los Angeles, California • San Francisco, California + 39 more
- Conditions
- Knee Injuries, Athletic Injuries
- Interventions
- Not listed
- Lead sponsor
- Steve Marshall
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4,800 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2011
- U.S. locations
- 3
- States / cities
- Colorado Springs, Colorado • Annapolis, Maryland • West Point, New York