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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:06 AM EDT

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Showing 97–120 of 965 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Light Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders

NCT00387179
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm
Interventions
Melatonin, Methylxanthine, Light Therapy
Drug · Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 25, 2009 · Synced Oct 20, 2026, 5:06 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)

NCT06292780
View directory record Official record
Conditions
Relapsed/Refractory Systemic Light Chain Amyloidosis
Interventions
Linvoseltamab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2035
U.S. locations
8
States / cities
Duarte, California • Denver, Colorado • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Benefits of Tanning in Fibromyalgia Patients

NCT00447083
View directory record Official record
Conditions
Fibromyalgia Syndrome
Interventions
UVB, Non-UVB
Device · Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
25 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 20, 2026, 5:06 AM EDT
Active, not recruiting Phase 1 Interventional

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

NCT00881920
View directory record Official record
Conditions
Lymphoma, Myeloma, Leukemia
Interventions
Kappa CD28 T cells
Biological
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2035
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Study of Low Level Laser Light Therapy to Improve Blood Circulation in People With Chronic Heel Pain

NCT01882725
View directory record Official record
Conditions
Defective; Circulation
Interventions
Erchonia HP Scanner (HPS)
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 14, 2015 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 4 Interventional

Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy

NCT02193568
View directory record Official record
Conditions
Adult Brain Tumor
Interventions
Arm I (light sedation), Arm II (intubated general anesthesia), Arm II (intubated general anesthesia), Arm I (light sedation)
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 1 Interventional

Tissue Oxygenation Measurements With Modulated Light (S-FLARE)

NCT01116297
View directory record Official record
Conditions
Breast Cancer
Interventions
Imaging with S-FLARE imaging system
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 20, 2026, 5:06 AM EDT
No Longer Available No phase listed Expanded access

Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

NCT00423826
View directory record Official record
Conditions
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous Condition, Secondary Myelofibrosis
Interventions
Busulfan, Cytarabine, Fludarabine phosphate, mycophenolate mofetil, tacrolimus, allogeneic hematopoietic stem cell transplantation, umbilical cord blood transplantation, total-body irradiation
Drug · Procedure · Radiation
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
Up to 69 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 20, 2026, 5:06 AM EDT
Not listed Not applicable Interventional

RYSE Family-based Behavioral Treatment for Childhood Obesity

NCT05212155
View directory record Official record
Conditions
Obesity, Childhood
Interventions
family-based behavioral treatment (FBT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years to 12 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Joplin, Missouri • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 20, 2026, 5:06 AM EDT
Terminated Phase 1 Interventional

Immunogenetic Profiling of Goeckerman Therapy in the Treatment of Psoriasis Vulgaris

NCT03662685
View directory record Official record
Conditions
Psoriasis Vulgaris, Psoriasis
Interventions
Goeckerman Therapy, Crude Coal Tar Only, Phototherapy Only
Other · Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 20, 2026, 5:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

NCT01207817
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Pupillometry
Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 23, 2010 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 2 Interventional

Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases

NCT00068068
View directory record Official record
Conditions
Liver Metastasis, Colorectal Neoplasms, Liver Neoplasms, Neoplasm Metastasis
Interventions
Talaporfin sodium (LS11), LED-based light infusion device, Light emitting diodes (LED), Photodynamic therapy, Phototherapy, Chemotherapy
Drug · Device · Procedure
Lead sponsor
Light Sciences LLC
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
5
States / cities
Denver, Colorado • Greenville, North Carolina • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2006 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 2 Interventional Results available

Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden

NCT00651937
View directory record Official record
Conditions
Multiple Myeloma, Primary Amyloidosis
Interventions
Melphalan, Stem Cell Infusion, Questionnaires, Granulocyte-colony stimulating factor (G-CSF), Apheresis
Drug · Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
60 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 20, 2026, 5:06 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Comparison Between Spectacles and Contact Lenses

NCT06905912
View directory record Official record
Conditions
Photophobia
Interventions
Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat

NCT01837719
View directory record Official record
Conditions
Human Immunodeficiency Virus Type 1 (HIV-1)
Interventions
Atazanavir, Cobicistat, Atazanavir/Cobicistat FDC
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 49 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2014 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles

NCT03312543
View directory record Official record
Conditions
Skin Aging
Interventions
Active Mask, Sham Mask
Device
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
35 Years to 70 Years · Female only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Broomall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Light Sensitization Study

NCT01327040
View directory record Official record
Conditions
Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian Rhythm
Interventions
light exposure
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 30 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

UVA Light Device to Treat COVID-19

NCT04572399
View directory record Official record
Conditions
Coronavirus
Interventions
UV Light Treatment
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 1Phase 2 Interventional

Scalp Psoriasis Treatment With a Fiber Optic Comb

NCT00007293
View directory record Official record
Conditions
Psoriasis
Interventions
UV-B Lightsource and Fiber Optic Comb
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 4, 2007 · Synced Oct 20, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional

Using Light Therapy for Mild Cognitive Impairment

NCT07651787
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Amyloid Pathology
Interventions
Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation, Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
55 Years to 95 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Broadband Light Treatment for Pigmented Skin Lesions

NCT05750914
View directory record Official record
Conditions
Pigmentation
Interventions
Broadband Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Victor, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT04505293
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 20, 2026, 5:06 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

NCT07573150
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 5:06 AM EDT
Completed Phase 2 Interventional Results available

Carboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer Who Are Light/Never Smokers

NCT01344824
View directory record Official record
Conditions
Lung Cancer
Interventions
bevacizumab, carboplatin, erlotinib hydrochloride, pemetrexed disodium
Biological · Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
4
States / cities
Asheville, North Carolina • Chapel Hill, North Carolina • New Bern, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Oct 20, 2026, 5:06 AM EDT