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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Limitation, Mobility Clear all
Not yet recruiting Not applicable Interventional

FES: Effect on Walking in the Real World and Participation in Daily Life in People With Multiple Sclerosis.

NCT07706114
View directory record Official record
Conditions
Multiple Sclerosis, Impaired Gait
Interventions
Use of functional electrical stimulation for extended duration on the participants' weaker limb
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
22 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lower Extremity Muscle and Function in the Elderly: Study 2

NCT01614392
View directory record Official record
Conditions
Mobility Limitation
Interventions
High velocity low force Power Training, Low velocity high force Power Training
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
70 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2018 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Impact of More Frequent PT Services

NCT04778475
View directory record Official record
Conditions
Mobility Limitation, Physical Disability, Stroke, Acute
Interventions
Intensive therapy, Standard of care therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sling Use and Functional Mobility in a Geriatric Population

NCT03921619
View directory record Official record
Conditions
Mobility Limitation
Interventions
Shoulder Sling
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Walk On! National Council on Aging Innovation Lab

NCT07368907
View directory record Official record
Conditions
Falls Prevention
Interventions
Walk On! Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

NCT07502885
View directory record Official record
Conditions
Sarcoma, Bone, Sarcoma, Soft Tissue, Gait Disorder
Interventions
Lab based 3D Gait Assessment, Wearable Inertial Sensors (In Lab and Remote), Functional Testing & Patient Reported Outcomes, Remote Wearable Sensor Assessment
Diagnostic Test · Device · Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
5 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

NCT04958642
View directory record Official record
Conditions
Niemann-Pick Disease, Type C
Interventions
Adrabetadex
Drug
Lead sponsor
Mandos LLC
Industry
Eligibility
4 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
15
States / cities
Birmingham, Alabama • Orange, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SmartHMD for Improved Mobility

NCT03781583
View directory record Official record
Conditions
Low Vision, Orientation, Mobility Limitation, Navigation, Spatial, Visual Impairment
Interventions
SmartHMD version 1, SmartHMD version 2, SmartHMD version 3, SmartHMD version 4
Device
Lead sponsor
James Weiland
Other
Eligibility
14 Years to 89 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting Phase 3 Interventional

SMART Exercise for PAD

NCT06032065
View directory record Official record
Conditions
Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
Interventions
Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
Behavioral · Dietary Supplement
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Life 2: Improving Fitness and Function in Elders

NCT00435188
View directory record Official record
Conditions
Aging, Mobility Limitations
Interventions
Multi-component physical activity counseling program
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
70 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Heat Therapy, Functional Capacity, and Vascular Health in Older Adults

NCT05706181
View directory record Official record
Conditions
Aging Well, Walking, Difficulty, Hyperemia
Interventions
Home-based leg heat therapy, Home-based sham therapy
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
55 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Functional Activity Strength Training

NCT05697497
View directory record Official record
Conditions
Walking, Difficulty
Interventions
Daily exercise intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
65 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Functional Fitness for Overweight or Obese Adults With Mobility Disabilities

NCT05880966
View directory record Official record
Conditions
Mobility Limitation, Overweight or Obesity, Physical Disability
Interventions
Functional Fitness
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

A Community Health Worker Program to Support Rural Older Adults

NCT03843333
View directory record Official record
Conditions
Frail Elderly, Cognitive Impairment, Mobility Limitation, Depressive Symptoms
Interventions
Tai Ji Quan: Moving for Better Balance, Behavioral Activation, Resource Navigation, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Vermont
Other
Eligibility
65 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Augusta, Maine • Lyme, New Hampshire • Montpelier, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Exercise for Adults With Limited Mobility

NCT05266573
View directory record Official record
Conditions
Mobility Limitation, Fall
Interventions
Exercise Group
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 100 Years
Enrollment
38 participants
Timeline
2015 – 2017
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Sensorimotor Locus of Balance Control in Elderly Gait

NCT03341728
View directory record Official record
Conditions
Ambulation Difficulty, Gait, Unsteady, Fall, Position Sense Disorders
Interventions
Optical flow perturbations, Normal walking
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke

NCT01180738
View directory record Official record
Conditions
Stroke, Difficulty Walking
Interventions
Body weight supported treadmill training, Overground walking training
Behavioral
Lead sponsor
Stephanie Miller
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Dose-response of Coordination Training for Older Adults.

NCT03629730
View directory record Official record
Conditions
Mobility Limitation
Interventions
Coordination training
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
70 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Limb Health and Socket Pressure in Response to Powered Ankle Protheses

NCT05112679
View directory record Official record
Conditions
Pressure Ulcer, Ankle, Prosthesis User, Prosthesis Durability, Mobility Limitation, Skin Wound, Amputation; Traumatic, Foot, Amputation, Limb Deficiencies
Interventions
PROPRIO FOOT® by Ossur & Empower ankle by Ottobock
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop

NCT01138995
View directory record Official record
Conditions
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis, Post-Cerebrovascular Accident (CVA) Hemiparesis
Interventions
Ness L300, Ankle-foot orthosis
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Downey, California • Long Beach, California • San Diego, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Jul 22, 2026, 2:19 AM EDT
Completed No phase listed Observational

The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease

NCT01055730
View directory record Official record
Conditions
Interstitial Lung Disease
Interventions
Pulmonary rehabilitation
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
19 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
5
States / cities
Concord, California • Daly City, California • New Haven, Connecticut + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

ENhancing Exercise With LIGHT to Improve Functioning in PAD

NCT06399900
View directory record Official record
Conditions
Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
Interventions
Far red light therapy, Sham light therapy, Home-based walking exercise
Device · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neural Operant Conditioning

NCT06113965
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Walking, Difficulty
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Minimizing Fall-Related Injury in Older Adults: a Motor Learning Approach

NCT05260034
View directory record Official record
Conditions
Fall Injury, Fall Patients, Mobility Limitation
Interventions
FAST Program, Otago Exercise Program
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Jul 22, 2026, 2:19 AM EDT