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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:18 AM EDT

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Showing 1–24 of 51 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Lipolysis Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting of the Flank With Alternate Treatment Parameters

NCT02081196
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Sacramento, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multiple CoolSculpting Treatment Study

NCT01814007
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
3
States / cities
Pleasanton, California • Walnut Creek, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Phase 1 Interventional

SGLT2i, Pioglitazone, and Ketone Production in T2D

NCT07053319
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Empagliflozin 25 MG, Pioglitazone 15 mg increased to 30 mg after 2 weeks plus Empagliflozin Placebo, Empagliflozin 25 mg/d plus Pioglitazone (15/30 mg/d)
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
30 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trim II for Noninvasive Lipolysis and Circumference Reduction of Abdomen.

NCT05398159
View directory record Official record
Conditions
Circumference Reduction of Abdomen
Interventions
Trim II
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
5
States / cities
Huntersville, North Carolina • Philadelphia, Pennsylvania • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 21, 2026, 5:18 AM EDT
Terminated Not applicable Interventional Results available

Multi-Center Traditional Feasibility Study of Radiofrequency Device

NCT04584099
View directory record Official record
Conditions
Body Fat
Interventions
Radiofrequency device treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
New York, New York • Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism

NCT04300049
View directory record Official record
Conditions
Insulin Sensitivity
Interventions
Glucagon Infusion, Saline
Drug · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Oct 21, 2026, 5:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Regular Activity on Physiology Between Recreational Athletes of Different Body Fatness

NCT05154422
View directory record Official record
Conditions
Obesity, Insulin Sensitivity
Interventions
Not listed
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Early Phase 1 Interventional

SGLT2i, Hepatic Glucose Production, and SNS

NCT07053293
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Empagliflozin 25 MG
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
30 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Regional Lipolysis Insulin Regulation

NCT06392854
View directory record Official record
Conditions
Obesity
Interventions
Insulin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SlimShape Device for Abdominal Fat and Circumference Reduction

NCT02999763
View directory record Official record
Conditions
Fat Disorder
Interventions
SlimShape
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 60 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Sacramento, California • Wayland, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aging, Exercise, and Hormonal Influences of Fat Metabolism

NCT00100451
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
exercise
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2001
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 21, 2026, 5:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

LED Device for Non-Invasive Lipolysis

NCT03171051
View directory record Official record
Conditions
Lipolysis
Interventions
950 nm LED Device, 1050nm Diode Laser Device
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Results available

Histological Study to Assess Safety and Efficacy of the TempSure Firm for Non-Invasive Lipolysis

NCT04878172
View directory record Official record
Conditions
Non-invasive Lipolysis
Interventions
TempSure Firm
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
New York, New York • Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 21, 2026, 5:18 AM EDT
Terminated Not applicable Interventional Results available

Histological Study on Safety and Efficacy of a RF Device Flexible Applicator for Non-Invasive Lipolysis

NCT04881175
View directory record Official record
Conditions
Lipolysis
Interventions
Non-Invasive Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Montclair, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Phase 2 Interventional

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

NCT05470504
View directory record Official record
Conditions
Insulin Receptor Mutation, Partial Lipodystrophy
Interventions
Pegvisomant
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Safety and Efficacy of REBORN System for Lipolysis Treatment

NCT05507528
View directory record Official record
Conditions
LIPOLYSIS
Interventions
reborn treatment
Device
Lead sponsor
Lightfective Ltd
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tennessee City, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 21, 2026, 5:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fat Tissue Microperfusion to Measure Leptin Secretion and Its Relations With Fat Breakdown in Humans

NCT00001722
View directory record Official record
Conditions
Healthy, Obesity
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Lipolysis and Improvement of Muscle Tone in Upper Arms

NCT04596241
View directory record Official record
Conditions
Fat Disorder
Interventions
BTL-899
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Hunt Valley, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 21, 2026, 5:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Thyroid and Fat Tissue Metabolism

NCT00312715
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Calcium and Lipid Metabolism

NCT00686192
View directory record Official record
Conditions
Obesity
Interventions
Calcium Carbonate
Dietary Supplement
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 40 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2002
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2008 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Phase 1 Interventional

SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia

NCT07053306
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Empagliflozin 25 MG
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
30 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Fat Perception in Humans (09-0873)

NCT01128400
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 21, 2026, 5:18 AM EDT
Recruiting Phase 1 Interventional

SGLTi, Hepatic Glucose Production and Ketogenesis

NCT05960656
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Empagliflozin 25 MG, Placebo
Drug · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
30 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 5:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Reduction of Abdominal Fat

NCT01101997
View directory record Official record
Conditions
Fat Reduction
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
5
States / cities
Sacramento, California • Coral Gables, Florida • Hunt Valley, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 21, 2026, 5:18 AM EDT