Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 9, 2026, 9:57 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 1,257 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Local Disease Clear all

Conditions: Pain Management
Interventions: Bupivacaine, Dexamethasone; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Infection
Interventions: Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis); Procedure · Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 687 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 10
States / cities: Farmington, Connecticut • Washington D.C., District of Columbia • Chicago, Illinois + 6 more

Conditions: Obstruction of Pelviureteric Junction
Interventions: Ropivacaine wound catheter, Saline wound catheter; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Months to 14 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts • Cincinnati, Ohio

Conditions: Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
Interventions: Bilateral Erector Spinae Plane Block (ESPB); Procedure
Lead sponsor: Stanford University; Other
Eligibility: 0 Years to 99 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Smoking
Interventions: Proactive outreach to counseling, Reactive outreach to counseling, Intensive counseling, Self-help; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Enrollment: 3,120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 3
States / cities: Palo Alto, California • Sepulveda, California • New York, New York

Conditions: Liver Cancer, Hepatocellular Carcinoma (HCC)
Interventions: Quality of life questionnaires; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 2
States / cities: Durham, North Carolina

Conditions: Sensation Diminished, Pinprick
Interventions: cooling device; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
Interventions: Control (Norepinephrine), Norepinephrine + Ascorbic Acid, Norepinephrine + L-NAME, Norepinephrine + L-NAME + Ascorbic Acid; Drug
Lead sponsor: The University of Texas at Arlington; Other
Eligibility: 18 Years to 35 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Arlington, Texas

Conditions: Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
Interventions: HD Study Electrode; Device
Lead sponsor: Albany Medical College; Other
Eligibility: 18 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Albany, New York

Conditions: Brain Cancer, Brain Metastases, Melanoma, Lung Cancer, Breast Cancer, HER2-positive Breast Cancer, Colorectal Cancer, Gastrointestinal Cancer, SRS, SRT, Whole Brain Radiation, Stereotactic Radiation, AGuIX, Nanoparticle, Cystic, Brain Tumor
Interventions: Stereotactic Radiation, AGuIX gadolinium-based nanoparticles, Placebo; Radiation · Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Prostate Cancer
Interventions: Local anesthesia; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years · Male only
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain
Interventions: SKY0402, Bupivacaine HCl; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 136 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 15
States / cities: Birmingham, Alabama • Mobile, Alabama • La Jolla, California + 10 more

Conditions: Situational Anxiety, Behavior
Interventions: Therapy dog presence, Standard-of-care basic behavior guidance; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 4 Years to 12 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Interventions: Low dose naltrexone, Placebo sugar capsules; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Anesthesia, Local
Interventions: Ropivacaine; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 6 Months to 18 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Osteoarthritis, Pain
Interventions: Exparel, Femoral Nerve Block Bupivacaine, Toradol, Morphine Sulfate; Drug
Lead sponsor: The New England Baptist Hospital; Other
Eligibility: 18 Years to 73 Years
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postoperative Pain, Acute, Postoperative Complications
Interventions: Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks, Thoracic epidural catheter; Procedure
Lead sponsor: Swedish Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Colon Polyp, Adenoma, Serrated Polyp, Recurrence, Local Neoplasm, Endoscopic Resection
Interventions: 6-month follow-up, 12-month follow-up; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 546 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 8
States / cities: Birmingham, Alabama • Aurora, Colorado • Chicago, Illinois + 5 more

Conditions: Bladder Extrophy, Surgery in Children
Interventions: Ropivacaine (Epidural analgesia) intermittent bolus, Ropivacaine (Epidural analgesia) continuous infusion, Chloroprocaine intermittent bolus, Chloroprocaine continuous infusion; Drug
Lead sponsor: Giorgio Veneziano; Other
Eligibility: Up to 18 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Anesthesia, Local
Interventions: 0.5 ml lidocaine + epinephrine 1:100,000, 1.0 ml lidocaine + epinephrine 1:100,000; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Autism, Autism Spectrum Disorder
Interventions: Transcranial direct current stimulation; Device
Lead sponsor: American University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Postoperative Pain
Interventions: Bupivacaine; Drug
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: Up to 8 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Uterine Cancer, Cervical Cancer
Interventions: Proton radiation therapy; Radiation
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lung Adenocarcinoma, Lung Neoplasms
Interventions: osimertinib, Local Ablative Therapy (LAT); Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Bethesda, Maryland

Search by objective public record fields.

Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy

The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine

Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study

TeleQuit Smoking Cessation Program

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

A Device to Determine Return of Sensation From Spinal Block

Local Antioxidant Therapy Vasoconstriction Effects in Different Races

Intraoperative Neuromonitoring Recording With a Novel SCS Paddle

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Local Anesthesia for Prostate Biopsy

Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augmentation

Impact of Therapy Dogs on Child Anxiety and Behavior During Local Anesthesia for Dental Procedures

Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome

Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

Minimally Invasive Esophagectomy Pain Control Trial

Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection

A Pilot Study Comparison of Programmed Intermittent Bolus Versus Continuous Infusion

Split Face Study of the Duration of Local Anesthetics - Fourth Arm

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Transversus Abdominis Plane Blocks for Infants and Children for Postoperative Pain Control

Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix

Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib