Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 12:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1129–1152 of 1,259 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Local Disease Clear all

Conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Small Cell, Neoplasm Recurrence, Local
Interventions: Rhenium (Re 188 P2045, BAY86-5284); Drug
Lead sponsor: Andarix Pharmaceuticals; Industry
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2025
U.S. locations: 2
States / cities: Iowa City, Iowa • Baltimore, Maryland

Conditions: Prostate Carcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
Interventions: Abiraterone Acetate, Antiandrogen Therapy, Apalutamide, Biopsy, Niraparib, Prednisone, Radiation Therapy; Drug · Procedure · Radiation
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Parkinson
Interventions: DBS; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 10 participants
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Postoperative, Delirium, Anesthesia, Local
Interventions: Ropivacaine HCL, sodium chloride; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Dysphagia
Interventions: bupivacaine hydrochloride 0.5% solution, 0.9% NaCl solution; Drug
Lead sponsor: Justin Parker Neurological Institute; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Patient Readmission, Pulmonary Disease, Chronic Obstructive, Heart Failure, Diabetes Mellitus Poor Control, Hypertension, Pneumonia
Interventions: Standard of Care, Enhanced Care; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: La Plata, Maryland

Conditions: Post-Operative Pain, Lumbar Laminectomy
Interventions: Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 12
States / cities: Phoenix, Arizona • Pasadena, California • Wichita, Kansas + 9 more

Conditions: Spinal Fusion, Pain Management
Interventions: EXPAREL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Miami, Florida • Columbus, Ohio • Philadelphia, Pennsylvania

Conditions: Breast Cancer
Interventions: hypofractionated radiation; Radiation
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Female only
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 3
States / cities: Dearborn, Michigan • Royal Oak, Michigan • Troy, Michigan

Conditions: Neuroblastoma
Interventions: External beam radiotherapy, proton beam RT; Radiation
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 12 Months to 18 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Acne Vulgaris
Interventions: DFD-03 Lotion, 0.1%, Tazorac Cream, 0.1%, DFD-03 Vehicle Lotion 0%, Tazorac Vehicle Cream 0%; Drug
Lead sponsor: Dr. Reddy's Laboratories Limited, India; Industry
Eligibility: 9 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Total Knee Arthroplasty
Interventions: Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Osteoarthritis, Pain
Interventions: Exparel, Femoral Nerve Block Bupivacaine, Toradol, Morphine Sulfate; Drug
Lead sponsor: The New England Baptist Hospital; Other
Eligibility: 18 Years to 73 Years
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Arteriovenous Fistula Occlusion
Interventions: Placebo, Ascorbic Acid, Cuprimine Oral Product; Drug
Lead sponsor: Southeast Renal Research Institute; Other
Eligibility: 18 Years to 90 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Pain, Anesthesia, Labor Pain
Interventions: Low volume bolus, High volume bolus; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain
Interventions: S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%), Placebo Peel; Drug
Lead sponsor: ZARS Pharma Inc.; Industry
Eligibility: 5 Years to 17 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Brain and Central Nervous System Tumors, Neuroblastoma
Interventions: temozolomide; Drug
Lead sponsor: Duke University; Other
Eligibility: 4 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2002
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hemophilia, Hemorrhage, Facelift Surgery
Interventions: 1%Tranexamic acid with standard local, 3% TXA, 1% TXA with local plus 3% TXA-soaked pledgets; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Anesthesia, Conduction, Osteoarthritis, Hip
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Bermuda Run, North Carolina

Conditions: Cancer
Interventions: FACBC PET-CT Imaging; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
Interventions: ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Liver Cancer, Hepatocellular Carcinoma (HCC)
Interventions: Quality of life questionnaires; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 2
States / cities: Durham, North Carolina

Conditions: Anesthesia, Local
Interventions: Not listed
Lead sponsor: Avanos Medical; Other
Eligibility: 18 Years and older
Enrollment: 767 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 8
States / cities: Washington D.C., District of Columbia • Gulf Breeze, Florida • Miami, Florida + 5 more

Conditions: Wound Infection, Fractures, Open, Surgical Site Infection
Interventions: Tobramycin Injection; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 3
States / cities: Lexington, Kentucky • Boston, Massachusetts • Nashville, Tennessee

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Rhenium Re 188 P2045 in Patients With Lung Cancer Who Have Received or Refused to Receive Prior Chemotherapy

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Intraoperative Investigation of a Directional Lead and Local Field Potentials for the Optimization of Stimulation Efficacy

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

Anesthetic to Reduce Dysphagia After Anterior Cervical Discectomy and Fusion Surgery

UM CRMC RecuR Score Pilot

HTX-011 in Spinal Surgery

PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery

Hypofractionated Regional Nodal Irradiation in Breast Cancer

Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma

A Study to Assess the Safety and Local Tolerability of DFD-03 (Tazarotene) Lotion, 0.1% Compared to Tazorac® Cream, 0.1% in the Topical Treatment of Acne Vulgaris

Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis

Drug Concentration and Volume on Adequate Labor Analgesia With PIEB

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Vascular Access Procedures in Children

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study

Pain and Sensation After Regional Anesthesia - Pilot Study

Validation of FACBC for Detection of Metastasis Among High-risk Prostate Cancer Patients With Presumed Localized Disease

iPACK Block With Dexamethasone For Total Knee Replacement

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

PACMAN Ultrasound Recording Data Collection

Tobramycin Injection to Prevent Infection in Open Fractures