Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 12:00 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1225–1248 of 1,259 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Local Disease Clear all

Conditions: Pain
Interventions: Femoral perineural infusion; Drug
Lead sponsor: National Institute of General Medical Sciences (NIGMS); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 2
States / cities: La Jolla, California • Gainesville, Florida

Conditions: Health Behavior
Interventions: Connect to Wellness; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Peripheral Artery Disease
Interventions: Wireless Lumee Oxygen Platform; Device
Lead sponsor: Profusa, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 3
States / cities: San Francisco, California

Conditions: Anesthesia, Local
Interventions: LET Gel after STAR Particle Application (Right or Left Arm), LET Gel Application without STAR Particle Application (Contralateral Arm); Device · Other
Lead sponsor: Emory University; Other
Eligibility: 10 Years to 21 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pain
Interventions: Liposomal Bupivicaine, 0.25% standard bupivicaine; Drug
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Falls Church, Virginia

Conditions: Serratus Anterior Plane Block, Transversus Thoracis Plane Block, Subcutaneous ICD
Interventions: Combined serratus anterior plane block and transversus thoracis plane block, Standard local infiltration technique; Procedure
Lead sponsor: New York Presbyterian Brooklyn Methodist Hospital; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Hand Surgery, Wrist Surgery, Elbow Surgery, Fracture Fixation, Dupuytren Contracture, Finger Fracture, Wrist Arthropathy, Distal Radius Fracture
Interventions: Liposomal bupivacaine (LB), Dexamethasone; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Colorectal Cancer, Metastatic Cancer
Interventions: FOLFIRI regimen, floxuridine, fluorouracil, irinotecan hydrochloride, leucovorin calcium, melphalan, hyperthermia treatment; Drug · Procedure
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Carotid Disease
Interventions: NeurOS; Device
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Infection
Interventions: Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis); Procedure · Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 687 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 10
States / cities: Farmington, Connecticut • Washington D.C., District of Columbia • Chicago, Illinois + 6 more

Conditions: General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions: Lidocaine; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 65 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Head and Neck Neoplasms, Neoplasm Recurrence, Local, Neoplasm Metastasis
Interventions: docetaxel (XRP6976), cisplatin, 5-fluorouracil (5-FU); Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 568 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2003
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Post Operative Surgical Site Infection
Interventions: Vancomycin antibiotic powder; Drug
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 80 Years
Enrollment: 1,036 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain
Interventions: S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%), Placebo Peel; Drug
Lead sponsor: ZARS Pharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Clinton Township, Michigan • New York, New York

Conditions: Local Anesthetics
Interventions: Lidocaine, normal saline, alkalinized lidocaine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 19 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cancer, Solid Tumor
Interventions: Personalized Synthetic Long Peptide Vaccine; Biological
Lead sponsor: Jaime Leandro Foundation for Therapeutic Cancer Vaccines; Other
Eligibility: 12 Years and older
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 6
States / cities: Beverly Hills, California • San Francisco, California • Santa Monica, California + 3 more

Conditions: Pain
Interventions: Oxymorphone; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain, Procedural Pain, Local Anesthesia, Mohs Surgery, Skin Cancer
Interventions: Active Vibration:TENS, Sham TENS; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 3
States / cities: Maple Grove, Minnesota • Minneapolis, Minnesota • Wyoming, Minnesota

Conditions: Family Relationships, Parent-Child Relationships
Interventions: PREP 8.0 curriculum developed by PREP, Within My Reach curriculum developed by PREP, Within Our Reach 8 Hours curriculum; Other
Lead sponsor: Children's Aid Society in Clearfield County; Other
Eligibility: 18 Years and older
Enrollment: 1,119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Clearfield, Pennsylvania

Conditions: Healthy, Inflammation, Mouth Disease, Pain
Interventions: Not listed
Lead sponsor: National Institute of Dental and Craniofacial Research (NIDCR); NIH
Eligibility: Not listed
Enrollment: 275 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity
Interventions: Not listed
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Contraception, Pain, Acute, Anesthesia, Local
Interventions: Buffered Lidocaine, Sham Comparator, Unbuffered lidocaine, Xylocaine jelly 2%, Surgilube; Drug · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 204 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Peripheral Neuropathy
Interventions: Axon Reflexes, Axon Flares, Self-Reported Signs & Symptoms of CIPN; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Head and Neck Cancer, Free Tissue Transfer
Interventions: Ropivicaine, Local Saline Infusion; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Continuous Femoral Nerve Block Following Total Knee Replacement

Training LHDs to Disseminate Evidence-Based Interventions to Small Worksites

Monitoring Local Tissue Oxygen Changes Using the Wireless Lumee Oxygen Platform in Correlation to TcPO2

Lidocaine Administration Using STAR Particles

Pain Management in Response to Exparel vs. Standard Bupivicaine

Serratus Anterior Plane Block Combined With Transversus Thoracic Muscle Plane Block Versus Conventional Local Anesthetic Infiltration for SICD Implantation: A Randomized Controlled Trial

The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Study of Regional Cerebral Oxygenation and Brain Blood Volume Changes During Carotid Endarterectomy Using the NeurOS System

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

Taxotere (Docetaxel) in 1st Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO)

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Pulsed Dye Laser (PDL) Therapy in Adults

Clinical Study to Evaluate the Effect of pH on Pain Upon Local Anesthetic Administration.

A Phase 1b/2, Multi-center, Single Arm Study to Assess the Safety and Efficacy of Neoantigen Synthetic Long Peptide Vaccines in Patients With Local Or Metastatic Solid Tumors

A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)

E-MOHS Trial of TENS and Vibration During Local Anesthesia

Local Evaluation of Real Relationships

Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth

Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRI

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer

Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps