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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Low Backache Clear all
Completed No phase listed Observational

Post Epidural Steroid Injection Follow-up

NCT04207606
View directory record Official record
Conditions
Lumbago, Lumbar Spinal Stenosis, Lumbar Disc Herniation
Interventions
Post Epidural Steroid Injection Follow-up
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Timeline
2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Phase 3 Interventional

Efficacy of Acupuncture for Chronic Low Back Pain

NCT00065585
View directory record Official record
Conditions
Low Back Pain
Interventions
Accupuncture
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 70 Years
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Oakland, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Sep 9, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional

Investigating Medical Massage Therapy for Patients With Sub-Acute Lower Back Pain

NCT07615816
View directory record Official record
Conditions
Lower Back Pain, Subacute Lower Back Pain, Medical Massage Therapy
Interventions
Medical Massage Therapy, Provider Directed Care
Procedure · Other
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Joint Base Lewis McChord, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Not yet recruiting Not applicable Interventional

Treatment of Chronic Lower Back Pain With a Combination of Electrical Stimulation, LED, and Laser Therapy

NCT07313826
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Active Neurolumen, Inactive Neurolumen
Device
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Lateral Branch Cooled Radiofrequency Denervation vs. Conservative Therapy for Sacroiliac Joint Pain

NCT03601949
View directory record Official record
Conditions
Sacroiliac Joint Pain
Interventions
SInergy Cooled Radiofrequency, Medical Management
Device · Other
Lead sponsor
Avanos Medical
Other
Eligibility
21 Years to 110 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
15
States / cities
Washington D.C., District of Columbia • Bloomington, Illinois • New Orleans, Louisiana + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Manual Therapy as a Form of Sensory Discrimination in Chronic Low Back Pain

NCT02757378
View directory record Official record
Conditions
Low Back Pain
Interventions
Neuroplasticity Explanation (Experimental), Biomechanical Explanation (Control)
Procedure
Lead sponsor
Kevin Farrell
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
5
States / cities
Moline, Illinois • Silvis, Illinois • Woodridge, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Sep 9, 2026, 11:57 PM EDT
Completed No phase listed Observational

Medial Branch Radiofrequency Ablation and Lumbar Multifidi

NCT03744260
View directory record Official record
Conditions
Spondylosis, Osteoarthritis
Interventions
Patients undergo ultrasound and lumbar MRI
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Sep 9, 2026, 11:57 PM EDT
Not listed Not applicable Interventional

Effect of Lumbar Manipulation on Intervertebral Motion, Pain, and Disability

NCT06294132
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham Lumbar Manipulation
Procedure
Lead sponsor
Ithaca College
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Orthotic Use for Chronic Low Back Pain

NCT00976664
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Shoe orthotic, Shoe Orthotic Wait Group
Device
Lead sponsor
National University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Trial of Inserting Prevalence Information Into Lumbar Spine Imaging Reports

NCT02015455
View directory record Official record
Conditions
Low Back Pain, Back Pain, Lumbar Pain, Backache
Interventions
Epidemiologic benchmarks included in lumbar imaging reports
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
250,401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
Oakland, California • Detroit, Michigan • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2022 · Synced Sep 9, 2026, 11:57 PM EDT
Not yet recruiting Phase 2 Interventional

Semaglutide for Low Back Pain

NCT07731256
View directory record Official record
Conditions
Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 Agonist
Interventions
Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
Birmingham, Alabama • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Spine Phenome Project

NCT05776771
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
10,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional

Clinician Satisfaction With the VERABAND™

NCT06080464
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
VERABAND information
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
La Jolla, California • Kansas City, Kansas • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Suspended Not applicable Interventional

The Influence of a Protein Nutrition Beverage on Exercise-based Rehabilitation Outcomes in Individuals with Spine Pain.

NCT04829448
View directory record Official record
Conditions
Low Back Pain
Interventions
Protein supplement
Dietary Supplement
Lead sponsor
Kamshad Raiszadeh, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Upright Back Posture Device Study

NCT03769246
View directory record Official record
Conditions
Back Pain, Postural Low Back Pain, Lower Back Pain
Interventions
Upright Go Device, Ergonomic Handout
Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Phase 4 Interventional

Opiate-Induced Tolerance & Hyperalgesia in Pain Patients

NCT00246532
View directory record Official record
Conditions
Chronic Low Back Pain, Opioid-induced Hyperalgesia
Interventions
Morphine, Placebo
Drug
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
18 Years to 70 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2012 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Phase 3 Interventional

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

NCT01427270
View directory record Official record
Conditions
Low Back Pain
Interventions
Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release, Placebo
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
170
States / cities
Alabaster, Alabama • Birmingham, Alabama • Gulf Shores, Alabama + 137 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2014 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Acute Low Back Pain Management

NCT01726803
View directory record Official record
Conditions
Low Back Pain
Interventions
Early Physical Therapy with Usual Care, Usual Care
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of a Potential Mechanisms of Spinal Manipulation in the Treatment of Low Back Pain

NCT00922220
View directory record Official record
Conditions
Low Back Pain
Interventions
stationary bike, lumbar extension exercise, spinal manipulative therapy
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 21, 2011 · Synced Sep 9, 2026, 11:57 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of Lumbopelvic Stabilization Exercises for Pregnancy-related Low Back Pain

NCT02606786
View directory record Official record
Conditions
Pregnancy-related Low Back Pain
Interventions
Lumbopelvic stabilization exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2017 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation

NCT00000410
View directory record Official record
Conditions
Herniated Disc, Low Back Pain
Interventions
Diskectomy, Non-surgical treatments
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 9, 2026, 11:57 PM EDT
Recruiting Phase 1 Interventional

Adia Med of Winter Park LLC Lower Back Pain Research Study

NCT07587047
View directory record Official record
Conditions
Chronic Mechanical Lower Back Pain, Lower Back Pain, Chronic Lower Back Pain
Interventions
Umbilical Cord Blood-Derived Stem Cells and Exosomes, Placebo IV
Biological · Other
Lead sponsor
Adia Med of Winter Park LLC
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winter Park, Florida
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Acupuncture for Chronic Low Back Pain in Older Adults

NCT04982315
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Standard Acupuncture, Enhanced Acupuncture
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
807 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
4
States / cities
Oakland, California • Walnut Creek, California • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 9, 2026, 11:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Retrospective Study to Identify New "Omics" Biomarkers of Chronic/Persistent Low Back Pain

NCT02037789
View directory record Official record
Conditions
Persistent/Chronic Low Back Pain
Interventions
Not listed
Lead sponsor
University of Parma
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2016 · Synced Sep 9, 2026, 11:57 PM EDT