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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:09 PM EDT

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Showing 121–144 of 231 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Low Vision Clear all
Completed Not applicable Interventional

VA Low Vision Intervention Trial

NCT00223756
View directory record Official record
Conditions
Vision, Low
Interventions
Low Vision Intervention - Outpatient Training Program
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

A Multi-Center Study of Reading Rehabilitation in Macular Disease

NCT00746668
View directory record Official record
Conditions
Age Related Maculopathy, Retinal Degeneration
Interventions
Module 1: Visual Awareness and Eccentric Viewing, Module 2: Control of Reading Eye Movements, Module 3: Reading Practice with RSVP
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2015 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Peripheral Prism Glasses for Hemianopia

NCT00494676
View directory record Official record
Conditions
Homonymous Hemianopia
Interventions
High power (57 prism diopter) peripheral prism glasses, Low power sham peripheral prism glasses
Device
Lead sponsor
Alexandra Bowers
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
12
States / cities
Birmingham, Alabama • Palo Alto, California • Jupiter, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 20, 2026, 6:09 PM EDT
Not yet recruiting Not applicable Interventional

Multisensory Rehabilitation of Vision Loss After Cortical Damage

NCT07659691
View directory record Official record
Conditions
Cortical Blindness
Interventions
Multisensory Rehabilitation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality Mobility Training System for Veterans With Vision Loss

NCT00333879
View directory record Official record
Conditions
Blindness
Interventions
Virtual Sound System
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

NCT04638660
View directory record Official record
Conditions
Dim Light Vision Disturbances
Interventions
Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle (Placebo)
Drug
Lead sponsor
Opus Genetics, Inc
Industry
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
17
States / cities
Newport Beach, California • Petaluma, California • Jacksonville, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality-Base Intelligent Orientation and Mobility Specialists Trial

NCT04639531
View directory record Official record
Conditions
Low Vision, Both Eyes
Interventions
Orientation and Mobility Training with VR-IOMSs, Orientation and Mobility Training with COMS, No Orientation and Mobility Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • Talladega, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.

NCT04049266
View directory record Official record
Conditions
Wet Macular Degeneration
Interventions
KSI-301, Aflibercept, Sham Procedure
Drug · Other
Lead sponsor
Kodiak Sciences Inc
Industry
Eligibility
50 Years and older
Enrollment
559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
59
States / cities
Phoenix, Arizona • Springdale, Arkansas • Bakersfield, California + 53 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 20, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Stem Cell Ophthalmology Treatment Study II

NCT03011541
View directory record Official record
Conditions
Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease, Optic Neuropathy, Nonarteritic Ischemic Optic Neuropathy, Optic Atrophy, Optic Nerve Disease, Glaucoma, Leber Hereditary Optic Neuropathy, Blindness, Vision Loss Night, Vision Loss Partial, Vision, Low, Retinopathy, Maculopathy, Macular Degeneration, Retina Atrophy
Interventions
Arm 1
Procedure
Lead sponsor
MD Stem Cells
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
2
States / cities
Westport, Connecticut • Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Terminated Phase 4 Interventional

Functional Vision in TBI

NCT01214070
View directory record Official record
Conditions
Brain Injuries, Visually Impaired Persons
Interventions
Vision Restoration Therapy, NVT Eye Scanning Therapy, Eccentric Viewing Training, Sham
Other · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 79 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 20, 2026, 6:09 PM EDT
Suspended Not applicable Interventional

V-NAV Usability Study: End Users Trying the Vortant Indoor Navigation Tool

NCT05647694
View directory record Official record
Conditions
Blindness and Low Vision
Interventions
V-NAV indoor navigation prototype
Other
Lead sponsor
Vortant Technologies, LLC
Other
Eligibility
12 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Weaverville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Phase 2 Interventional

Predictors of Driving Performance and Successful Mobility - Rehabilitation in Patients With Medical Eye Condition

NCT00013377
View directory record Official record
Conditions
Low Vision
Interventions
Low vision
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Phase 2 Interventional

Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost

NCT00637130
View directory record Official record
Conditions
Open-angle Glaucoma, Ocular Hypertension
Interventions
Travoprost ophthalmic solution, 0.0008%, Travoprost ophthalmic solution, 0.001%, Travoprost ophthalmic solution, 0.0012%, TRAVATAN, Vehicle
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2012 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Scotoma Perimetry Oculomotor Training

NCT05456581
View directory record Official record
Conditions
Macular Degeneration, Central Visual Impairment
Interventions
'Scotoma awareness' Training, Control Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Phase 4 Interventional Results available

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

NCT03323164
View directory record Official record
Conditions
Glaucoma; Drugs, Normal Tension Glaucoma, Primary Open-angle Glaucoma
Interventions
Timolol Maleate, Brimonidine Tartrate
Drug
Lead sponsor
Wills Eye
Other
Eligibility
18 Years to 90 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 31, 2020 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peripheral Vision Training Study

NCT03141164
View directory record Official record
Conditions
Visual Impairment, Cognitive Change
Interventions
computerized training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 20, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vision Loss Impact on Navigation in Virtual Reality

NCT06047717
View directory record Official record
Conditions
Stroke, Ischemic, Quadrantanopia, Hemianopsia, Homonymous, Hemianopia, Homonymous, Hemianopia, Hemianopsia, Occipital Lobe Infarct, Visual Field Defect, Peripheral, Vision Loss Partial, Quadrantanopsia, Stroke Hemorrhagic
Interventions
Virtual Reality Driving Task
Other
Lead sponsor
University of Rochester
Other
Eligibility
21 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Phase 2 Interventional

Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma

NCT00317577
View directory record Official record
Conditions
Glaucoma, Open Angle
Interventions
brimonidine, timolol
Drug
Lead sponsor
Chicago Center for Vision Research
Other
Eligibility
30 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
12
States / cities
Little Rock, Arkansas • Gainesville, Florida • Palm Beach Gardens, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2006 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Validating a Self-fitting Hearing Aid

NCT05246904
View directory record Official record
Conditions
Hearing and Vision Loss
Interventions
Fitting algorithm
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Accessible Weight Loss for Adults With Low Vision: A Feasibility Study

NCT05419063
View directory record Official record
Conditions
Overweight and Obesity
Interventions
weight loss strategies, text-based and email feedback
Behavioral
Lead sponsor
Towson University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 20, 2026, 6:09 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Implementing Artificial Intelligence to Prevent Vision Loss From Diabetes

NCT07559292
View directory record Official record
Conditions
Vision Disorders, Diabetes
Interventions
AI, Usual Practice
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
22 Years and older
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Assessing the Impact of eSight Go At-Home Usage in Individuals With Visual Impairment

NCT07149259
View directory record Official record
Conditions
Low Vision Aids
Interventions
At Home Use
Device
Lead sponsor
Brooks Rehabilitation
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 20, 2026, 6:09 PM EDT
Withdrawn Not applicable Interventional

A Study to See if Low Level Laser Light Therapy (LLLT) Can Improve the Condition of Nonalcoholic Steatohepatitis (NASH)

NCT03163810
View directory record Official record
Conditions
Nonalcoholic Steatohepatitis
Interventions
Erchonia Verju Laser, Erchonia EVRL Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 20, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Artificial Intelligence and Augmentative and Alternative Communication AAC

NCT06599996
View directory record Official record
Conditions
Cerebral Palsy, Cortical Visual Impairment
Interventions
Testing artificial intelligence algorithms for interpreting gestures
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Oct 20, 2026, 6:09 PM EDT