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ClinicalTrials.gov public records Last synced Oct 6, 2026, 7:03 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 134 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Lower Extremity Musculoskeletal Injury Clear all
Completed No phase listed Observational

Predictive Models for Spine and Lower Extremity Injury After Discharge From Rehab

NCT02776930
View directory record Official record
Conditions
Musculoskeletal Injury, Spinal Injuries, Leg Injuries
Interventions
Not listed
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 45 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Fort Bragg, North Carolina • Fort Bliss, Texas • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 6, 2026, 7:03 PM EDT
Recruiting No phase listed Observational

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

NCT04536103
View directory record Official record
Conditions
Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
Interventions
MRI
Diagnostic Test
Lead sponsor
Xiaojuan Li
Other
Eligibility
18 Years to 50 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Terminated Not applicable Interventional Results available

Foot and Ankle Range of Motion (Stretching) Apparatus

NCT00527748
View directory record Official record
Conditions
Plantar Fasciitis, Flatfoot, Calcaneus Fractures
Interventions
Non-Measuring Ankle Exerciser
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 6, 2026, 7:03 PM EDT
Recruiting Not applicable Interventional

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

NCT04875052
View directory record Official record
Conditions
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
Interventions
Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 35 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 6, 2026, 7:03 PM EDT
Not listed Not applicable Interventional

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

NCT05457205
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle
Interventions
Electrical neuromodulation
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 6, 2026, 7:03 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peer Support for Patients With Diabetic Foot Ulcers

NCT06004219
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetes Complications, Peripheral Neuropathy
Interventions
Peer counseling group
Behavioral
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Pomona, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Phase 2Phase 3 Interventional

Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities

NCT00280943
View directory record Official record
Conditions
Hip Fractures, Osteoporosis
Interventions
Long-term care facilities in the intervention arm will receive education and feedback audit on performance
Behavioral
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 6, 2026, 7:03 PM EDT
Active, not recruiting Not applicable Interventional

Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury

NCT02274116
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
SHAM - Intermittent Room Air - room air mixture, AIH - Intermittent Hypoxia - hypoxia air mixture
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed No phase listed Observational

Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up

NCT00478894
View directory record Official record
Conditions
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
14 Years to 55 Years
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2025
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Initial Graft Tension and ACL Surgery

NCT00434837
View directory record Official record
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Initial graft tension during ACL reconstruction surgery
Procedure
Lead sponsor
Rhode Island Hospital
Other
Eligibility
15 Years to 50 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed No phase listed Observational

Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study

NCT04771741
View directory record Official record
Conditions
Bunion of Unspecified Foot, Bunionette of Unspecified Foot, Hammertoe, Ankle Fractures, Achilles Tendon Surgery
Interventions
Acetominophen, Toradol, Meloxicam, Cyclobenzaprine, Lyrica
Drug
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years to 99 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 6, 2026, 7:03 PM EDT
Terminated Not applicable Interventional

Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes

NCT00121537
View directory record Official record
Conditions
Wounds, Compartment Syndromes
Interventions
Wound Care -Wound Vacuum Assisted Closure (VAC), Wound Care - Wet to Dry Dressing Changes
Device · Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 6, 2026, 7:03 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Biologic Therapy to Prevent Osteoarthritis After ACL Injury

NCT03968913
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Anakinra injection, sterile saline injection
Drug · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Adolescent Normative Sport Movement Analysis

NCT05068544
View directory record Official record
Conditions
Lower Extremity Problem, Musculoskeletal Injury
Interventions
Not listed
Lead sponsor
MultiCare Health System Research Institute
Other
Eligibility
13 Years to 25 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Puyallup, Washington
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Does Omeprazole Decrease Intestinal Calcium Absorption?

NCT00582972
View directory record Official record
Conditions
Osteoporosis, Achlorhydria, GERD, Hip Fracture
Interventions
Omeprazole
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 6, 2026, 7:03 PM EDT
Recruiting Not applicable Interventional

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

NCT07244211
View directory record Official record
Conditions
Femoral Neck Fractures
Interventions
Hip arthroplasty, Internal fixation
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
21
States / cities
Irvine, California • Los Angeles, California • San Francisco, California + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Active, not recruiting Phase 3 Interventional

Dronabinol After Arthroscopic Surgery

NCT05335252
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) Study

NCT01360099
View directory record Official record
Conditions
Osteoporosis, Bone Diseases, Metabolic, Hip Fractures
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 6, 2026, 7:03 PM EDT
Withdrawn Phase 2 Interventional

A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women

NCT00787358
View directory record Official record
Conditions
Hip Fracture
Interventions
ZT-031, placebo
Drug · Other
Lead sponsor
Zelos Therapeutics
Industry
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2009 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Not applicable Interventional

Surgical Treatment for Hallux Rigidus

NCT01048450
View directory record Official record
Conditions
Hallux Limitus, Hallux Rigidus
Interventions
Joint Resection- Keller Procedure, Joint Fusion, Hemi-metallic Joint Implant
Radiation · Procedure
Lead sponsor
American College of Foot and Ankle Surgeons
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
6
States / cities
Greeley, Colorado • Des Moines, Iowa • Scituate, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2011 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Not applicable Interventional

Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention

NCT05007366
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Knee Injuries, Cartilage, Articular, Gait
Interventions
Real-time gait biofeedback, Sham real-time gait biofeedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 6, 2026, 7:03 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Micro-Doppler Radar: A Gold Standard Comparison

NCT05521126
View directory record Official record
Conditions
Musculoskeletal Injury, Anterior Cruciate Ligament Injuries
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Annville, Pennsylvania • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 6, 2026, 7:03 PM EDT
Completed Not applicable Interventional Results available

Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots

NCT03848949
View directory record Official record
Conditions
Joint Pain, Trouble Balancing
Interventions
Evenup
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 6, 2026, 7:03 PM EDT
Completed No phase listed Observational

Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment Syndrome

NCT01077934
View directory record Official record
Conditions
Compartment Syndrome
Interventions
near-infrared spectroscopy
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
13 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Oct 6, 2026, 7:03 PM EDT