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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Lumbago Clear all
Completed Not applicable Interventional Results available

Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain

NCT06814470
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Virtual reality guided imagery acupuncture treatment (VRGAIT), Virtual reality guided imagery acupuncture treatment control
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 20, 2026, 12:19 AM EDT
Not listed Not applicable Interventional

Dry Needling Effects on Cortical Excitability

NCT05111691
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Sep 20, 2026, 12:19 AM EDT
Withdrawn Not applicable Interventional

Transcranial Magnetic Stimulation for Low Back Pain

NCT02070016
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2015 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Central Mechanisms of Intervention for Low Back Pain

NCT01406847
View directory record Official record
Conditions
Low Back Pain
Interventions
Spinal Manipulation, Spinal Mobilization, Static Touch
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 20, 2026, 12:19 AM EDT
Recruiting Not applicable Interventional

Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

NCT05556902
View directory record Official record
Conditions
Blood Pressure, Low Back Pain, Hypertension
Interventions
Permanent Epidural Spinal Cord Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 20, 2026, 12:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electrical Impedance Myography of Neck and Low Back Pain

NCT02159677
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
EIM Measurements
Device
Lead sponsor
Skulpt, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Sep 20, 2026, 12:19 AM EDT
Terminated Phase 4 Interventional Results available

Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain

NCT05409443
View directory record Official record
Conditions
Sacroiliac Joint Complex, Low Back Pain
Interventions
Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Lumbar Spine Muscle Degeneration Inhibits Rehabilitation-Induced Muscle Recovery

NCT03442374
View directory record Official record
Conditions
Disc Degeneration, Low Back Pain
Interventions
Exercise
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 85 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Mindfulness and Chronic Low Back Pain

NCT03354585
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
mindfulness training, non-mindfulness training, book-listening
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Manipulation, Exercise, and Self-Care for Low Back Pain

NCT00269347
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Spinal Manipulation, Exercise, Self-care
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 22, 2005 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Predicting Patients' Response to Spinal Manipulation

NCT00285649
View directory record Official record
Conditions
Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Usual Medical Care
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years to 55 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Sep 20, 2026, 12:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Home Program Education for Patients With Low Back Pain

NCT02427438
View directory record Official record
Conditions
Low Back Pain, Lumbago, Spinal Instability
Interventions
Video, Handout
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional

OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department

NCT06987578
View directory record Official record
Conditions
Acute Pain
Interventions
OMT vs. Ibruprofen
Other
Lead sponsor
St. Joseph's Regional Medical Center, New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Lumbopelvic Manipulation on Neuromuscular Activity of Back & Hip Muscles in Adults With Chronic Low Back Pain

NCT01861418
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Lumbopelvic Manipulation, Sham manipulation
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
20 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional Results available

Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation

NCT00484159
View directory record Official record
Conditions
Low Back Pain
Interventions
Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine, Radiofrequency denervation
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2011 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Phase 2 Interventional

Psychosocial Treatment for Acute Low Back Pain

NCT00000418
View directory record Official record
Conditions
Acute Low Back Pain
Interventions
Psychosocial intervention
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1977 – 2001
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2013 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of the Compression Belt for Patients With Sacroiliac Joint Pain

NCT01559948
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbopelvic stabilization exercise, Sacroiliac joint belt
Behavioral · Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Sep 20, 2026, 12:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

NCT07112404
View directory record Official record
Conditions
Pain, Back Pain, Lower Back Pain, Quality of Life
Interventions
Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Phase 4 Interventional Results available

The BEST Trial: Biomarkers for Evaluating Spine Treatments

NCT05396014
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM), Duloxetine
Behavioral · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
1,014 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Redwood City, California • San Diego, California • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Comparative Mechanisms of Psychosocial Chronic Pain Treatments

NCT02133976
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
cognitive therapy, mindfulness training, behavioral therapy, treatment as usual
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
521 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Examining Effects of Aerobic Exercise on Pain Sensation

NCT03546153
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis

NCT00000411
View directory record Official record
Conditions
Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 20, 2026, 12:19 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Core Strength in the Warfighter With a Novel Device

NCT06797830
View directory record Official record
Conditions
Core Strengthening, Posture, Low Back Pain
Interventions
AllCore
Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years to 50 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 20, 2026, 12:19 AM EDT
Completed Phase 2 Interventional Results available

Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

NCT02460692
View directory record Official record
Conditions
Cannabis, Low Back Pain, Neuropathic Pain
Interventions
Placebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
19 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 20, 2026, 12:19 AM EDT