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ClinicalTrials.gov public records Last synced Nov 11, 2026, 7:47 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 134 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Lumbar Spinal Stenosis Clear all

Conditions: Spinal Stenosis, Low Back Pain
Interventions: Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection, Epidural local anesthetic injection; Procedure · Drug
Lead sponsor: University of Washington; Other
Eligibility: 50 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 10
States / cities: Redwood City, California • Roseville, California • Denver, Colorado + 7 more

Conditions: Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
Interventions: Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon; Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 232 participants
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Spinal Stenosis
Interventions: Interspinous Spacer device, Interspinous Process Distraction Device; Device
Lead sponsor: Synthes USA HQ, Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 10
States / cities: Santa Monica, California • New Haven, Connecticut • Minneapolis, Minnesota + 7 more

Conditions: Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
Interventions: Not listed
Lead sponsor: Baxano Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 11
States / cities: Fullerton, California • Los Angeles, California • Carmel, Indiana + 8 more

Conditions: Lumbar Spinal Stenosis
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 90 Years
Enrollment: 239 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2023
U.S. locations: 7
States / cities: Denver, Colorado • Decatur, Georgia • Ann Arbor, Michigan + 4 more

Conditions: Spondylosis, Spondylolisthesis, Neurogenic Claudication, Foraminal Stenosis
Interventions: Chewing gum; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Degenerative Disc Disease, Spondylolisthesis, Stenosis
Interventions: Modulus ALIF System; Device
Lead sponsor: NuVasive; Industry
Eligibility: 18 Years and older
Enrollment: 123 participants
Timeline: 2022 – 2024
U.S. locations: 5
States / cities: Orange, California • San Diego, California • Atlanta, Georgia + 2 more

Conditions: Lumbar Spinal Stenosis
Interventions: MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection; Device · Drug
Lead sponsor: Coastal Orthopedics & Sports Medicine; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Lumbar Spinal Stenosis
Interventions: opana then darvocet then placebo, opana then placebo then darvocet, placebo then opana then darvocet, Placebo then darvocet then opana, Darvocet then opana then placebo, Darvocet then placebo then opana; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 50 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Spondylolisthesis
Interventions: Not listed
Lead sponsor: NuVasive; Industry
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 9
States / cities: Jacksonville, Florida • Kissimmee, Florida • Savannah, Georgia + 6 more

Conditions: Spinal Stenosis Lumbar
Interventions: Williams flexion protocol, Focused spinal stenosis rehabilitation; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 40 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Osteochondrosis, Spinal Osteophytosis, Spinal Stenosis, Spondylitis, Spondylosis
Interventions: Intraoperative spinal measurement system; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Lumbar Spine Stenosis Central Canal
Interventions: Percutaneous Lumbar Decompression, Sham lumbar decompression; Device
Lead sponsor: Napa Pain Institute; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Napa, California

Conditions: Lumbar Spinal Stenosis
Interventions: Manual Therapy and Exercise, Intramuscular Electroacupuncture; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Orlando, Florida • Boston, Massachusetts

Conditions: Lumbar Spinal Stenosis
Interventions: MILD, Interspinous Process Decompression; Device
Lead sponsor: Stryker Instruments; Industry
Eligibility: 18 Years and older
Enrollment: 8,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 2386
States / cities: Athens, Alabama • Bay Minette, Alabama • Birmingham, Alabama + 1287 more

Conditions: Lumbar Spinal Stenosis
Interventions: Superion® Indirect Decompression System (IDS); Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 45 Years and older
Enrollment: 1,674 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 66
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 60 more

Conditions: Spinal Surgery for Lumbar Spinal Stenosis (LSS)
Interventions: Wrist based activity tracker wear, Basic Study Activities, Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives; Behavioral · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 85 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lumbar Spinal Stenosis
Interventions: Liposomal bupivacaine; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Lumbar Spine Stenosis, Lumbar Spine Degeneration
Interventions: Not listed
Lead sponsor: OpalGenix, Inc; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania

Conditions: Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions: MILD Procedure, Epidural Steroid Injection; Procedure · Drug
Lead sponsor: Vertos Medical, Inc.; Industry
Eligibility: 65 Years and older
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 12
States / cities: Chula Vista, California • Fresno, California • Murrieta, California + 9 more

Conditions: Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia, Depression, Maladaptive Coping, Lumbar Spinal Stenosis, Insomnia, Sacroiliac Joint Pain, Lateral Hip and Thigh Pain, Anxiety, Dementia, Recent Leg Length Discrepancy
Interventions: Patient-Centered Care, Imaging-Directed Care; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years to 89 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • Richmond, Virginia

Conditions: Lumbar Spinal Stenosis
Interventions: flexion distraction, placebo control; Procedure · Other
Lead sponsor: National University of Health Sciences; Other
Eligibility: 50 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 1
States / cities: Lombard, Illinois

Conditions: Degenerative Spondylolisthesis, Lumbar Spinal Stenosis
Interventions: LimiFlex, Fusion Instrumentation, Decompression, Fusion; Device · Procedure
Lead sponsor: Empirical Spine, Inc.; Industry
Eligibility: 25 Years to 80 Years
Enrollment: 299 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 28
States / cities: Tempe, Arizona • Oakland, California • Redwood City, California + 24 more

Conditions: Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions: bilateral transforaminal epidural steroid injections; Drug
Lead sponsor: Marshfield Clinic Research Foundation; Other
Eligibility: 40 Years to 90 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Marshfield, Wisconsin

Search by objective public record fields.

Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)

Perioperative Local Anesthesia Block in Spine Surgery

A Study of the In-Space Device for Treatment of Moderate Spinal Stenosis

RAMP Study: A Study Comparing Two Lumbar Fusion Procedures

Predictors of Decompressive Laminectomy Outcomes

Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum

Retrospective Modulus ALIF Study

Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis

Lumbar Stenosis Outcomes Research II

XLIF® vs. MAS®TLIF for the Treatment of Symptomatic Lumbar Degenerative Spondylolisthesis With or Without Central Stenosis.

Focused Spinal Stenosis Rehabilitation Program for Lumbar Spinal Stenosis

Proprio Spine Measurement Tool

Comparative Study of Sham Versus Mild® Procedure in Patients Diagnosed With Symptomatic Lumbar Central Canal Stenosis

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Postmarket Registry for Evaluation of the Superion® Spacer

Activity Post Spinal Surgery Engagement Trial

Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults

The MiDAS ENCORE Study

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

Chiropractic Dosage for Lumbar Stenosis

LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis

Bilateral Transforaminal Epidural Steroid Injections for Degenerative Lumbar Spinal Stenosis