- Conditions
- Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
- Interventions
- Propranolol Hcl 40mg Tab, Placebo oral tablet
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
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Showing 1–24
of 313
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Back Pain, Chronic Low Back Pain, Internal Disc Disruption, Degenerative Disc Disease
- Interventions
- BIOSTAT BIOLOGX, Saline
- Biological · Drug
- Lead sponsor
- Spinal Restoration, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 20
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Chula Vista, California + 17 more
- Conditions
- Lumbar Spinal Stenosis
- Interventions
- Amniotic Fluid Allograft, Dexamethasone sodium phosphate
- Drug
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Degenerative Disc Disease
- Interventions
- Not listed
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 9
- States / cities
- South Bend, Indiana • Southfield, Michigan • Missoula, Montana + 5 more
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 4
- States / cities
- Orange, California • Jacksonville, Florida • Charlotte, North Carolina
- Conditions
- Lumbar Spondylosis, Lumbar Spondylolisthesis, Adult Degenerative Lumbar Scoliosis
- Interventions
- teriparatide, Placebo
- Biological
- Lead sponsor
- Shane Burch
- Other
- Eligibility
- 60 Years to 90 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Degenerative Lumbar Spondylolisthesis
- Interventions
- Use of OP-1 Putty in Uninstrumented posterolateral fusion
- Device
- Lead sponsor
- Olympus Biotech Corporation
- Industry
- Eligibility
- 18 Years to 81 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2005
- U.S. locations
- 5
- States / cities
- New Haven, Connecticut • Chicago, Illinois • Royal Oak, Michigan + 2 more
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse
- Biological
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 5
- States / cities
- Santa Monica, California • Greenwood Village, Colorado • Loveland, Colorado + 2 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- BMAC & Allograft, Iliac Crest Bone Graft
- Procedure
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2020
- U.S. locations
- 3
- States / cities
- New York, New York • Westbury, New York
- Conditions
- Degenerative Disc Disease, Spinal Fusion
- Interventions
- TGplPTH1-34 in fibrin, Autologous Bone Graft
- Combination Product · Other
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 15
- States / cities
- La Jolla, California • Boulder, Colorado • Washington D.C., District of Columbia + 11 more
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Interventions
- Not listed
- Lead sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Odessa, Florida
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spinal Instability, Lumbar Spine Degeneration
- Interventions
- Standard analgesia use [Oxygen], Standard analgesia use [Hydromorphone], Standard analgesia use [Volatile Anesthesia], Standard analgesia use [Fentanyl], Multi-modal pain management [Acetaminophen + Gabapentin], Multi-modal pain management [Fentanyl], Multi-modal pain management [Intravenous Ketamine], Multi-modal pain management [Valium + Gabapentin]
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Lumbar Spinal Stenosis
- Interventions
- Superion® Indirect Decompression System (IDS)
- Device
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 1,674 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 66
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 60 more
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- nanOss Bioactive - posterolateral gutter
- Device
- Lead sponsor
- Pioneer Surgical Technology, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 3
- States / cities
- La Jolla, California • San Francisco, California • Columbia, Missouri
- Conditions
- Lumbar Disc Disease
- Interventions
- SIGNUS MOBIS PEEK Cage, SIGNUS MOBIS II ST Cage
- Device
- Lead sponsor
- Signus Medizintechnik GmbH
- Industry
- Eligibility
- 18 Years to 89 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- East Syracuse, New York
- Conditions
- Diskectomy
- Interventions
- Discectomy with anular repair
- Procedure
- Lead sponsor
- Anulex Technologies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 750 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 34
- States / cities
- Huntsville, Alabama • Phoenix, Arizona • San Diego, California + 25 more
- Conditions
- Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
- Interventions
- Botulinum toxin type A, Isometric Yoga-like exercise, Placebo
- Drug · Behavioral
- Lead sponsor
- Manhattan Physical Medicine and Rehabilitation, LLP
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Manhattan, New York
- Conditions
- Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
- Combination Product
- Lead sponsor
- Seton Healthcare Family
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Spondylolisthesis
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 9
- States / cities
- Jacksonville, Florida • Kissimmee, Florida • Savannah, Georgia + 6 more
- Conditions
- Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
- Interventions
- Massage Therapy
- Other
- Lead sponsor
- Cook Children's Health Care System
- Other
- Eligibility
- 7 Years to 19 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
- Drug · Diagnostic Test
- Lead sponsor
- Catherine R. Olinger
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
- Interventions
- OSTEOAMP, Infuse
- Other · Device
- Lead sponsor
- Bioventus LLC
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 9
- States / cities
- New Haven, Connecticut • Wichita, Kansas • Paducah, Kentucky + 6 more
- Conditions
- Lumbar Spinal Stenosis
- Interventions
- Non-randomized ACADIA® Facet Replacement System, Randomized ACADIA® Facet Replacement System, Randomized Instrumented posterolateral fusion (PLF)
- Device
- Lead sponsor
- Globus Medical Inc
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 390 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2017
- U.S. locations
- 28
- States / cities
- Beverly Hills, California • Los Angeles, California • Rancho Mirage, California + 23 more
- Conditions
- Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
- Interventions
- Selective Nerve Root Block
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio