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ClinicalTrials.gov public records Last synced May 22, 2026, 12:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 311 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Lumbar Spine Disease Clear all
Suspended Not applicable Interventional
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Spondylolisthesis, Grade 1, Neurogenic Claudication
Interventions
Pedicle Lengthening Osteotomy with Altum® Device, Control
Device
Lead sponsor
Innovative Surgical Designs
Industry
Eligibility
40 Years to 80 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2020 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Lumbar Degenerative Disease, Lumbar Degenerative Disc Disease, Degenerative Spine
Interventions
ISOVUE 300 Observation, ISOVUE 300 Feedback
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced May 22, 2026, 12:11 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
Interventions
Selective Nerve Root Block
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease (DDD)
Interventions
Lumbar Interbody Fusion Devices
Device
Lead sponsor
Spine and Scoliosis Research Associates
Other
Eligibility
18 Years to 110 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
San Francisco, California • New York, New York • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced May 22, 2026, 12:11 AM EDT
Terminated Phase 1 Interventional
View directory record Official record
Conditions
Lumbar Spondylosis
Interventions
Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
Device · Drug
Lead sponsor
Matthew Pingree
Other
Eligibility
22 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced May 22, 2026, 12:11 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Interventions
Superion® IDS, Direct decompression Surgery
Device · Procedure
Lead sponsor
VertiFlex, Incorporated
Industry
Eligibility
45 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Birmingham, Alabama • Carlsbad, California • Celebration, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced May 22, 2026, 12:11 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interlaminar Decompression
Procedure
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
13
States / cities
Jonesboro, Arkansas • Los Angeles, California • Napa, California + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced May 22, 2026, 12:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced May 22, 2026, 12:11 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
One-level or two-level anterior lumbar interbody fusion, InQu Bone Graft Extender and Substitute mixed with BMAC, Synthes Spinal Instrumentation
Procedure · Biological · Device
Lead sponsor
Kansas Joint and Spine Institute
Network
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2012 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
Interventions
Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic, Muscle relaxant during maintenance anesthesia, Pain control with fentanyl, Bispectral Index (BIS) monitoring for depth of anesthesia, Spinal Anesthesia, Midazolam administered during spinal anesthesia, Cerebrospinal fluid collection, Administration of intrathecal morphine
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced May 22, 2026, 12:11 AM EDT
Terminated Phase 3 Interventional
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Lumbar Transforaminal Epidural Corticosteroid Injection, Physical Therapy, Observation
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 64 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Daly City, California • Mill Valley, California • Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced May 22, 2026, 12:11 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Spinal Disease
Interventions
Not listed
Lead sponsor
DC2 Healthcare
Industry
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 10, 2014 · Synced May 22, 2026, 12:11 AM EDT
Active, not recruiting Phase 3 Interventional
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease
Interventions
SB-01 For Injection, Sham Needle
Drug
Lead sponsor
Spine BioPharma, Inc
Industry
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Napa, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced May 22, 2026, 12:11 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection
Device · Drug
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2013 · Synced May 22, 2026, 12:11 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Disc Herniation
Interventions
Two-Week Post-Operative Restriction, Six-Week Post-Operative Restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
electric dry needling, manipulation, conventional physical therapy
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
50 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Canton, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced May 22, 2026, 12:11 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
HEALOS and Leopard Cage, Leopard Cage and Autograft
Device
Lead sponsor
Advanced Technologies and Regenerative Medicine, LLC (ATRM)
Other
Eligibility
18 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
17
States / cities
Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
Interventions
Ketorolac, Acetaminophen, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced May 22, 2026, 12:11 AM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Vertebral Metastasis
Interventions
Conformal High Dose Intensity Modulated Radiation Therapy
Radiation
Lead sponsor
Ronald McGarry
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced May 22, 2026, 12:11 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
Interventions
MagnetOs Flex Matrix, Trinity Elite
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Hartford, Connecticut • Columbia, Maryland • Bloomfield Hills, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced May 22, 2026, 12:11 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
Interventions
ALIF
Device
Lead sponsor
Camber Spine Technologies
Industry
Eligibility
22 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced May 22, 2026, 12:11 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis
Interventions
Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
Procedure
Lead sponsor
Greenwich Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
5
States / cities
Greenwich, Connecticut • Boston, Massachusetts • Burlington, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Spondylosis
Interventions
Immediate PT, Rest until pain resolves
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 19 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Denver, Colorado • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Lower Back Pain, Lumbar Spondylosis
Interventions
Music Therapy
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced May 22, 2026, 12:11 AM EDT