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ClinicalTrials.gov public records Last synced Nov 4, 2026, 8:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Lumbar Stenosis Clear all

Conditions: Spinal Surgery for Lumbar Spinal Stenosis (LSS)
Interventions: Wrist based activity tracker wear, Basic Study Activities, Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives; Behavioral · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 85 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
Interventions: Ketorolac, Acetaminophen, Placebo; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 75 Years
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Lumbar Spinal Stenosis
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 90 Years
Enrollment: 239 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2023
U.S. locations: 7
States / cities: Denver, Colorado • Decatur, Georgia • Ann Arbor, Michigan + 4 more

Conditions: Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions: Multimodal Analgesia, Patient controlled analgesia; Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: Not listed
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Lumbar Spinal Stenosis
Interventions: Non-randomized ACADIA® Facet Replacement System, Randomized ACADIA® Facet Replacement System, Randomized Instrumented posterolateral fusion (PLF); Device
Lead sponsor: Globus Medical Inc; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 390 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2017
U.S. locations: 28
States / cities: Beverly Hills, California • Los Angeles, California • Rancho Mirage, California + 23 more

Conditions: Lumbar Spinal Stenosis, Thoracic Spinal Stenosis
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lumbar Central Canal Stenoses, Neural Foraminal Stenoses
Interventions: Upright CT; Radiation
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Spondylosis, Spondylolisthesis, Neurogenic Claudication, Foraminal Stenosis
Interventions: Chewing gum; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions: Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo; Drug · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Lumbar Spinal Stenosis
Interventions: Epidural Steroid Injection with Lavage; Procedure
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Degenerative Disc Disease, Spinal Stenosis, Spondylosis, Spondylolisthesis
Interventions: ViviGen Cellular Bone Matrix; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Lumbar Spinal Stenosis
Interventions: Epidural steroid injection plus physical therapy, Epidural steroid injection; Other
Lead sponsor: Franklin Pierce University; Other
Eligibility: 50 Years to 90 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2018
U.S. locations: 4
States / cities: Denver, Colorado • Peoria, Illinois • Keesler Air Force Base, Mississippi + 1 more

Conditions: Spinal Stenosis Lumbar
Interventions: Lumbar Spinal Stenosis; Other
Lead sponsor: Parker University; Other
Eligibility: 48 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions: Lumbar Interbody Fusion with Autograft, Lumbar Interbody Fusion with NeoFuse; Biological
Lead sponsor: Mesoblast, Ltd.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 5
States / cities: Santa Monica, California • Greenwood Village, Colorado • Loveland, Colorado + 2 more

Conditions: Patients With Spinal Stenosis Indicated for LLIF
Interventions: One-level lateral lumbar interbody fusion with Indirect Decompression, One-level lateral lumbar interbody fusion with Direct Decompression; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Spinal Stenosis, Inflammation
Interventions: Dexmedetomidine group, Placebo group; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: New York, New York

Conditions: Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
Interventions: Interbody cage (titanium), Interbody cage (PEEK); Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Lumbar Spinal Stenosis
Interventions: Kenalog Injectable Product, Decadron Phosphate, Injectable, Epidural Steroid Injection; Drug · Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia, Depression, Maladaptive Coping, Lumbar Spinal Stenosis, Insomnia, Sacroiliac Joint Pain, Lateral Hip and Thigh Pain, Anxiety, Dementia, Recent Leg Length Discrepancy
Interventions: Patient-Centered Care, Imaging-Directed Care; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years to 89 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • Richmond, Virginia

Conditions: Lumbar Spinal Stenosis, Intermittent Claudication
Interventions: Superion™ Interspinous Spacer, X-STOP® IPD® Device; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 45 Years and older
Enrollment: 391 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2017
U.S. locations: 32
States / cities: Phoenix, Arizona • Tucson, Arizona • Beverly Hills, California + 28 more

Conditions: Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Spondylolisthesis
Interventions: Liposomal bupivacaine; Drug
Lead sponsor: Allina Health System; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Saint Paul, Minnesota

Conditions: Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions: Not listed
Lead sponsor: Baxano Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 5
States / cities: Tampa, Florida • Indianapolis, Indiana • Baton Rouge, Louisiana + 2 more

Conditions: Lumbar Spinal Stenosis
Interventions: electric dry needling, manipulation, conventional physical therapy; Other
Lead sponsor: Alabama Physical Therapy & Acupuncture; Other
Eligibility: 50 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Canton, Georgia

Conditions: Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis, Lumbar Spondylosis, Lumbago With Sciatica, Left Side, Lumbago With Sciatica, Right Side
Interventions: Osteopathic Manipulative Treatment (OMT); Procedure
Lead sponsor: Rowan University; Other
Eligibility: 18 Years to 84 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey

Search by objective public record fields.

Activity Post Spinal Surgery Engagement Trial

Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes

Predictors of Decompressive Laminectomy Outcomes

Multimodal Analgesia Versus Routine Care Pain Management

A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis

Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery

Prospective Evaluation of Upright Versus Supine CT Myelography of the Lumbar Spine

Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum

Effect of RECK in Posterior Spinal Fusion

Epidural Lavage Study for Lumbar Stenosis

Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery

Epidural Steroid Injection Versus Epidural Steroid Injection and Manual Physical Therapy and Exercise in the Management of Lumbar Spinal Stenosis

Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT

Pilot Study on the Effect of Dexmedetomidine on Inflammatory Responses in Patients Undergoing Lumbar Spinal Fusion

Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages

Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

Investigating Superion™ In Spinal Stenosis

Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion

A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures

Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis

Cost Effectiveness of OMT for Chronic Low Back Pain