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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Lymphoedema Clear all
Completed Phase 2 Interventional

Pycnogenol for the Treatment of Lymphedema of the Arm in Breast Cancer Survivors

NCT00064857
View directory record Official record
Conditions
Lymphedema, Breast, Cancer
Interventions
Pycnogenol
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 21, 2008 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Not applicable Interventional

Identification of a Screening Tool and Treatment of Lymphedema Secondary to the Management of Breast Cancer Study

NCT00282529
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
High Risk Lymphedema Education and Device Intervention
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

LYT-100 in Patients With BCRL

NCT04243837
View directory record Official record
Conditions
Breast Cancer Related Lymphoedema, Lymphoedema
Interventions
LYT-100 BCRL, Placebo BCRL
Drug
Lead sponsor
PureTech
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Duarte, California • Los Angeles, California • Maitland, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Home-Based Lymphedema Care Program (HBLCP) in Improving Lymphedema Self-Care in Head and Neck Cancer Survivors

NCT02170272
View directory record Official record
Conditions
Head and Neck Cancer, Lymphedema
Interventions
Home-based Lymphedema Care Program
Behavioral
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Non-Invasive Imaging for Cording in Breast Cancer Patients

NCT01427166
View directory record Official record
Conditions
Breast Cancer
Interventions
Non invasive venous ultrasound
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Jul 22, 2026, 9:04 AM EDT
Completed No phase listed Observational

Exercise Program of Breast Cancer Patients Undergoing Chemotherapy With or Without Radiation

NCT01157767
View directory record Official record
Conditions
Breast Cancer
Interventions
standardized regimen of exercises, including a warm-up period, ROM arm exercises, and strength training exercises.
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Phase 4 Interventional Results available

Low Level Laser Treatment and Breast Cancer Related Lymphedema

NCT00852930
View directory record Official record
Conditions
Lymphedema
Interventions
laser and MLD combined, laser alone, manual lymphatic drainage
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Jul 22, 2026, 9:04 AM EDT
Completed No phase listed Observational

Efficacy Verification in Early Diagnosis and Management of Lymphedema Through Home Body Water Analyzer

NCT06580743
View directory record Official record
Conditions
Breast Cancer
Interventions
No intervention
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Not applicable Interventional

Measuring Skin Elasticity in Lymphedema Patients

NCT03313999
View directory record Official record
Conditions
Diagnoses Disease, Lymphedema
Interventions
Lymphedema Indentometer
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Not applicable Interventional

Preventing Lymphedema in Axillary Lymph Node Dissection

NCT03428581
View directory record Official record
Conditions
Lymphedema, Breast Cancer, Melanoma
Interventions
ALND with ARM +/- LVB, ALND
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 22, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs

NCT06944041
View directory record Official record
Conditions
Limb Volume, Measuring Edema
Interventions
STO3 sensor (Structure Inc., Boulder, CO)
Other
Lead sponsor
The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lymphedema Progression Screening Using MRI

NCT02611557
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Manual lymphatic drainage therapy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Jul 22, 2026, 9:04 AM EDT
Recruiting No phase listed Observational

A Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management

NCT03248310
View directory record Official record
Conditions
Lymphedema
Interventions
Quality of Life Assessments
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 80 Years
Enrollment
600 participants
Timeline
2017 – 2026
U.S. locations
3
States / cities
Harrison, New York • New York, New York • Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Recombinant Human Hyaluronidase in Treating Lymphedema in Patients With Cancer

NCT01928030
View directory record Official record
Conditions
Lymphedema, Malignant Neoplasm
Interventions
recombinant human hyaluronidase
Biological
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Jul 22, 2026, 9:04 AM EDT
Completed No phase listed Observational

Breast Cancer Lymphedema: Role of Insulin Resistance/FOXC2

NCT00383604
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients

NCT02412241
View directory record Official record
Conditions
Oral Cavity Cancer, Oropharyngeal Cancer, Lymphedema, Fibrosis
Interventions
LEF measures, Technical measure
Other · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Clinical Evaluation of a Novel Wearable Compression Technology in the Treatment of Lymphedema, An Open-Label Controlled Study

NCT04659564
View directory record Official record
Conditions
Breast Cancer Related Lymphedema, Lymphedema of Upper Arm, Lymphedema, Quality of Life
Interventions
User of Dayspring device
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Los Altos, California • Morgan Hill, California
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Treatment Trial for Post-Thrombotic Syndrome

NCT00633971
View directory record Official record
Conditions
Post Thrombotic Syndrome
Interventions
complex lymphedema therapy
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Jul 22, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Developing a Checklist of Lymphedema Symptoms in Patients With Head and Neck Cancer

NCT00840814
View directory record Official record
Conditions
Head and Neck Cancer, Lymphedema
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
20 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Jul 22, 2026, 9:04 AM EDT
Recruiting No phase listed Observational

A Real-World Registry of Chronic Wounds and Ulcers

NCT02280733
View directory record Official record
Conditions
Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions
Usual care
Other
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
300,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

Immunotherapy for the Treatment of Breast Cancer Related Upper Extremity Lymphedema (BCRL)

NCT02494206
View directory record Official record
Conditions
Breast Cancer, Upper Extremity Lymphedema
Interventions
QBX258
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Jul 22, 2026, 9:04 AM EDT
Terminated Not applicable Interventional Results available

Placebo-Controlled Therapeutic Trial for the Prevention of Lymphedema

NCT01893879
View directory record Official record
Conditions
Lymphedema, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
placebo for study drug, (RS)2-(3-benzoylphenyl)-propionic acid, laboratory biomarker analysis
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Jul 22, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Massage for Post Breast Surgery

NCT02250898
View directory record Official record
Conditions
Postmastectomy Lymphedema Syndrome, Pain, Shoulder Mobility Impairment, Breast Surgery
Interventions
Myofascial Massage Therapy, Global Relaxation Massage
Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 79 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Jul 22, 2026, 9:04 AM EDT
Not listed No phase listed Observational

Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment

NCT01273909
View directory record Official record
Conditions
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Acquired Lymphedema, Congenital Lymphedema
Interventions
Perforator Flap Breast Reconstruction, Vascularized Lymph Node Transfer
Procedure
Lead sponsor
The National Institute of Lymphology
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
3
States / cities
Chicago, Illinois • New Orleans, Louisiana • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2014 · Synced Jul 22, 2026, 9:04 AM EDT