- Conditions
- Nosocomial Bacteremia, Nosocomial Fungemia, MRSA Colonization, MRSA Infection, VRE Colonization, VRE Infection
- Interventions
- Daily bathing with Chlorhexidine based product
- Behavioral
- Lead sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 5,300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 4
- States / cities
- Baltimore, Maryland • St Louis, Missouri • New York, New York + 1 more
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Showing 1–16
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- Conditions
- Nosocomial Bacteremia, MRSA Colonization, MRSA Infection, VRE Colonization, VRE Infection
- Interventions
- Bathing with Chlorhexidine Impregnated Washcloths
- Procedure
- Lead sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 14,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 7
- States / cities
- Chicago, Illinois • Iowa City, Iowa • Baltimore, Maryland + 4 more
- Conditions
- Staphylococcus Aureus Bacteremia
- Interventions
- Cefazolin, Penicillin, Clindamycin, Vancomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging
- Drug · Other · Radiation
- Lead sponsor
- University of Melbourne
- Other
- Eligibility
- Not listed
- Enrollment
- 8,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Infective Endocarditis
- Interventions
- daptomycin, daptomycin and gentamicin
- Drug
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 4
- States / cities
- Denver, Colorado • Detroit, Michigan • Philadelphia, Pennsylvania
- Conditions
- MRSA Infection, Bacteremia, ABSSSI, Pneumonia
- Interventions
- Not listed
- Lead sponsor
- CPL Associates
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Staphylococcus Aureus Bacteremia, Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia
- Interventions
- Ceftaroline fosamil
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 27
- States / cities
- Birmingham, Alabama • Sacramento, California • San Francisco, California + 23 more
- Conditions
- Bacteremia, Staphylococcal Infection, Sepsis, Infection
- Interventions
- MicroPhage S. aureus / MSSA / MRSA Blood Culture Test (prototype)
- Other
- Lead sponsor
- MicroPhage, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 712 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 3
- States / cities
- Evanston, Illinois • Baltimore, Maryland
- Conditions
- MRSA Bloodstream Infection, MRSA Bacteremia, MRSA Right-sided Endocarditis, Covid19
- Interventions
- Exebacase
- Drug
- Lead sponsor
- ContraFect
- Industry
- Eligibility
- 18 Years and older
- U.S. locations
- 2
- States / cities
- Butte, Montana • Toledo, Ohio
- Conditions
- Bacteremia
- Interventions
- Not listed
- Lead sponsor
- MicroPhage, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 764 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 3
- States / cities
- Tuscon, Arizona • Los Angeles, California • Charleston, South Carolina
- Conditions
- Staphylococcus Aureus Bacteremia
- Interventions
- Early Dual IV Antibiotic Therapy - MRSA, Early Dual IV Antibiotic Therapy - MSSA, Single Agent IV Antibiotic Therapy - MRSA, Single Agent IV Antibiotic Therapy - MSSA
- Drug
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Bloodstream Infection, Sepsis Bacterial, MRSA Bacteremia, Vancomycin
- Interventions
- T2Bacteria® Panel (direct-from-blood testing), Usual Care
- Other
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Endocarditis, Bacterial, Infective Endocarditis
- Interventions
- daptomycin, vancomycin
- Drug
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 2
- States / cities
- Greenville, North Carolina • Cleveland, Ohio
- Conditions
- Staphylococcus Aureus
- Interventions
- Not listed
- Lead sponsor
- Michael E. DeBakey VA Medical Center
- Federal
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Bacteremia, Fungemia, Bloodstream Infection
- Interventions
- FilmArray testing, Antimicrobial Stewardship, Bacterial culture, Susceptibility testing
- Device · Behavioral · Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- Up to 99 Years
- Enrollment
- 743 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Sepsis, Sepsis Mrsa, Sepsis Bacteremia, Antimicrobial - Induced Nephropathy, Sepsis, Severe, Septic Shock, Septic Syndrome
- Interventions
- Multifaceted de-implementation strategy to reduce vancomycin overuse
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- Not listed
- Enrollment
- 52,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 4
- States / cities
- Atlanta, Georgia • Baltimore, Maryland • St Louis, Missouri + 1 more
- Conditions
- Bacteremia
- Interventions
- Daptomycin, Vancomycin, Ceftaroline
- Drug
- Lead sponsor
- Sharp HealthCare
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 2
- States / cities
- La Mesa, California • San Diego, California