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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: MSM Clear all
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Getting to Zero Among HHI MSM in the American South

NCT05075967
View directory record Official record
Conditions
HIV Infections
Interventions
Health Access Coalitions, Social Media, Peer Support, Promoting Human Autonomy Support & Empathy (PHASE)
Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
15 Years and older · Male only
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Feasibility and Preliminary Impact of a mHealth App on Reducing STI Risk in Black MSM PrEP Users

NCT05395754
View directory record Official record
Conditions
STI, Sexually Transmitted Diseases, Pre-exposure Prophylaxis
Interventions
App Intervention
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse

NCT03577301
View directory record Official record
Conditions
HIV Infections
Interventions
Clinic-based Delivery, Remote Delivery, Multi-modal Delivery
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Miami, Florida • Detroit, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Jul 23, 2026, 5:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Alcohol and Sex Risk mHealth-Enhanced Brief Intervention for BLMSM

NCT04821427
View directory record Official record
Conditions
Heavy Drinking and Sexual Risk Behavior
Interventions
Brief mhealth intervention + mobile messaging to reduce sexual risk behavior and heavy drinking
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tell Me More ("Dime Mas")

NCT06063083
View directory record Official record
Conditions
HIV, Mental Health Issue
Interventions
Tell Me More ("Dime Mas"), Peer Ambassador Stories [Listen Miami ("Oye Miami")], Standard Community Outreach
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM

NCT03511131
View directory record Official record
Conditions
Hiv, Adolescent Behavior, Sex, Safe
Interventions
Queer Sex Ed, Keep It Up, Keep It Up-Control, Young Men's Health Project
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 18 Years · Male only
Enrollment
1,306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Jul 23, 2026, 5:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

ADAPT-POL New Orleans: Adaptation of Prevention Techniques With Popular Opinion Leader

NCT00252109
View directory record Official record
Conditions
HIV Infections
Interventions
Popular Opinion Leader
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Jul 23, 2026, 5:12 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Anal Dysplasia Study of Men Who Have Sex With Men Living With HIV

NCT01663558
View directory record Official record
Conditions
Anal Dysplasia, Human Papilloma Virus, HIV
Interventions
imiquimod, ablative
Drug · Procedure
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South

NCT05087680
View directory record Official record
Conditions
HIV Prevention
Interventions
ACTPrEP, Enhanced Standard of Care
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fostering Resilience to Psychosocial and HIV Risk in Indian MSM

NCT02556294
View directory record Official record
Conditions
HIV Infection, Sexual Behavior, Health Behavior
Interventions
Self-acceptance based intervention, HIV/STI counseling and testing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
608 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Real-Time, Remote Monitoring System for Home-Based HIV Testing

NCT02876926
View directory record Official record
Conditions
HIV
Interventions
"Smart" home-based test for HIV, Home-based testing only, Reminder letters for clinic-based testing
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

PrEPared and Strong: Clinic-Based PrEP for Black MSM

NCT02167386
View directory record Official record
Conditions
HIV/AIDS
Interventions
Enhanced PrEP Adherence, Standard PrEP Adherence
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Male only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

UTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM

NCT04710901
View directory record Official record
Conditions
Sexually Transmitted Diseases, HIV Infections, Implementation Science, Substance Use, MSM
Interventions
uTECH + YMHP, YMHP, uTECH
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
388 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 4 Interventional Results available

Antiretroviral Therapy (ART) Persistence in Different Body Compartments in HIV Negative MSM

NCT04039217
View directory record Official record
Conditions
ART, HIV
Interventions
Biktarvy
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mhealth for PrEP Adherence by Young Adult MSM, Phase 2

NCT04633200
View directory record Official record
Conditions
Hiv
Interventions
DOT mobile app
Other
Lead sponsor
Environment and Health Group, Inc.
Industry
Eligibility
18 Years to 35 Years · Male only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Results available

Brief Alcohol Intervention for HIV-Infected Men Who Have Sex With Men (MSM) in a Primary Care Setting

NCT01328743
View directory record Official record
Conditions
Hazardous Drinking, HIV
Interventions
Brief alcohol intervention
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Jul 23, 2026, 5:12 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Leveraging Chatbot to Improve PrEP in the Southern United States

NCT05968755
View directory record Official record
Conditions
HIV Prevention, PrEP Awareness, PrEP Uptake
Interventions
A chatbot designed to promote PrEP awareness and uptake for Black MSM, General educational messages
Device · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
4
States / cities
Miami, Florida • Pembroke Pines, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 4 Interventional Results available

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

NCT03842436
View directory record Official record
Conditions
HIV/AIDS, Substance Use Disorders, Adherence, Medication
Interventions
Digital pill, Truvada
Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boylston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 1Phase 2 Interventional

Culturally Sensitive Intervention to Improve Retention in HIV Care for Latino MSM

NCT01457066
View directory record Official record
Conditions
HIV
Interventions
Peer Navigator Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 26, 2015 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors

NCT00497081
View directory record Official record
Conditions
Substance Abuse, HIV Infections
Interventions
mirtazapine, placebo
Drug
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years to 60 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 4, 2015 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Serosorting Intervention for HIV Negative MSM

NCT02128594
View directory record Official record
Conditions
STDs
Interventions
Serosorting Intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older · Male only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multilevel Gaming Intervention for Persons on PrEP

NCT02611362
View directory record Official record
Conditions
MSM, PrEP, HIV Risk
Interventions
IMB Gaming Intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Jul 23, 2026, 5:12 AM EDT
Completed No phase listed Observational

Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men

NCT00919997
View directory record Official record
Conditions
Nonneoplastic Condition, Precancerous Condition
Interventions
DNA analysis, polymerase chain reaction, fluorescence activated cell sorting, questionnaire administration, study of socioeconomic and demographic variables, study of high risk factors
Genetic · Other · Procedure
Lead sponsor
AIDS Malignancy Consortium
Network
Eligibility
18 Years and older · Male only
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2015 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 4 Interventional Results available

A Demonstration Project to Add Pre- or Post-exposure Prophylaxis to Combination HIV Prevention Services

NCT01781806
View directory record Official record
Conditions
HIV Prevention
Interventions
emtricitabine 200mg/tenofovir 300mg
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Jul 23, 2026, 5:12 AM EDT