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Showing 1–24 of 256 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: MTBI - Mild Traumatic Brain Injury Clear all
Completed Not applicable Interventional

Virtual Reality- Working Memory Retraining

NCT03786276
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury
Interventions
VR-WMR-Only, Exercise-only, Active VR-WMR
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Sep 17, 2026, 7:20 AM EDT
Not yet recruiting Not applicable Interventional

Effectiveness of VestAid App

NCT06683417
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury, Vestibular Disease, Balance Deficits, Vestibular Disorders, Dizziness
Interventions
Vestibular Rehabilitation Aid, Standard of care vestibular rehabilitation
Device · Other
Lead sponsor
BlueHalo
Industry
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Phase 1 Interventional

Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy

NCT06665633
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
Interventions
Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
Drug · Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting Phase 1 Interventional

Regulation of Emotion, Sleep Extension, and mTBI

NCT06883006
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Sleep Extension
Behavioral
Lead sponsor
Merrimack College
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
North Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes

NCT04796207
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE)
Interventions
Fish Oil (DPA+EPA 2:1 ratio) Capsules, High Oleic Safflower Oil Capsules
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional

Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)

NCT04549532
View directory record Official record
Conditions
Concussion, Mild
Interventions
Targeted Multidomain, Behavioral Management
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 49 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI

NCT05524402
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury, Anxiety
Interventions
TOR-C 1, TOR-C 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

NCT05320822
View directory record Official record
Conditions
Concussion, Brain
Interventions
Active Rehab (Group 2), Progressive Return to Activity (Group 1)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 17, 2026, 7:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Balance and Mild Traumatic Brain Injury (TBI)

NCT01377454
View directory record Official record
Conditions
Brain Concussion, Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
12 Years to 40 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

NCT05762796
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Phase 2 Interventional Results available

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

NCT01611194
View directory record Official record
Conditions
Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
Interventions
Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms
Drug
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
5
States / cities
Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

NCT07282691
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Salus University
Other
Eligibility
18 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients

NCT00580918
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
functional magnetic resonance imaging fMRI
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2003
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 17, 2026, 7:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Australian UCSF Concussion in Athletes

NCT05769296
View directory record Official record
Conditions
Concussion, Mild
Interventions
Headpulse measurements
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting Not applicable Interventional

Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)

NCT06855186
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI)
Interventions
Symptom-Targeted Approach to Rehabilitation for Concussion
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Wahiawa, Hawaii • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 17, 2026, 7:20 AM EDT
Completed No phase listed Observational

Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)

NCT02812225
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
BrainPulse
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
5 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial for Vestibular Treatment in Concussion

NCT03600324
View directory record Official record
Conditions
Vestibular Disorder, Mild Traumatic Brain Injury
Interventions
T-REV
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 50 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Colorado Springs, Colorado • Marine Corps Base Camp Lejeune, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 17, 2026, 7:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Field Implementation of iDETECT

NCT02529618
View directory record Official record
Conditions
Concussion, Brain Trauma
Interventions
integrated Display Enhanced Testing for Cognitive Impairment and mild traumatic brain injury (iDETECT), Riddell High Impact Technology (HIT) System, i1 Biometrics Vector Mouth Guard
Device
Lead sponsor
Emory University
Other
Eligibility
14 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Atlanta, Georgia • College Park, Georgia • Marietta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Sep 17, 2026, 7:20 AM EDT
Withdrawn Not applicable Interventional

Cranial-nerve Non-invasive Neuromodulation (CN-NINM) for Balance Deficits After Mild Traumatic Brain Injury (Pilot Trial)

NCT02109198
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Active CN-NINM PoNS, Sham CN-NINM PoNS
Device
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Sep 17, 2026, 7:20 AM EDT
Completed No phase listed Observational

EyeBOX Concussion Study and Registry

NCT03966404
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX device
Diagnostic Test
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury

NCT03799458
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Active High-definition transcranial direct current stimulation (HD-tDCS), Sham High-definition transcranial direct current stimulation (HD-tDCS)
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 59 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 17, 2026, 7:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

NCT04124029
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
No Intervention is used for this study but all subjects will be asked to complete electroencephalogram (EEG) testing and an MRI scan., No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.
Device · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 90 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 17, 2026, 7:20 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Implementation of an Evidence-Based Educational Resource for Children With Mild Traumatic Brain Injury

NCT07414303
View directory record Official record
Conditions
Concussion, Mild Traumatic Brain Injury
Interventions
Post-mTBI Educational Resource
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
8 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
3
States / cities
Frisco, Texas • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 17, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI

NCT03478059
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Concussion, Brain
Interventions
Cognitive and Motor Dual-task Intervention
Behavioral
Lead sponsor
Allina Health System
Other
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 17, 2026, 7:20 AM EDT