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Showing 1–24 of 93 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Male Infertility Clear all
Withdrawn Not applicable Interventional

Safety and Efficacy of Freezing and Thawing of Human Eggs in Assisted Reproductive Technology

NCT00451009
View directory record Official record
Conditions
Infertility
Interventions
Viacell's product Media Kits
Device
Lead sponsor
ViaCell
Industry
Eligibility
21 Years to 35 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
4
States / cities
San Ramon, California • South Miami, Florida • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated May 28, 2014 · Synced Sep 5, 2026, 1:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele

NCT00044369
View directory record Official record
Conditions
Varicocele, Male Infertility, Hypospermatogenesis, Non-Obstructive Azoospermia
Interventions
Varicocele repair
Procedure
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
2
States / cities
Camden, New Jersey • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2006 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Testicular Evaluation of Azoospermia Using Micro-Ultrasound

NCT06941922
View directory record Official record
Conditions
Azoospermia
Interventions
Not listed
Lead sponsor
Paul Shin
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 5, 2026, 1:08 AM EDT
Completed Not applicable Interventional

Andrositol® TEST as Diagnostic Assay to Predict the Fertilization Potential in IVF

NCT03677011
View directory record Official record
Conditions
Male Infertility
Interventions
Andrositol® Test
Diagnostic Test
Lead sponsor
Lo.Li.Pharma s.r.l
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 5, 2026, 1:08 AM EDT
Terminated Not applicable Interventional Results available

Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients

NCT04206800
View directory record Official record
Conditions
Infertility, Male
Interventions
Ejaculatory abstinence less than 24 hours
Diagnostic Test
Lead sponsor
Boston IVF
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prospective Study on Power Prenatal Vitamins for Males on YO Score At-home Sperm Test Results

NCT05951075
View directory record Official record
Conditions
Spermatogenesis and Semen Disorders, Infertility, Male
Interventions
Power Prenatal for Sperm
Dietary Supplement
Lead sponsor
The Bird and Be Co Inc
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 5, 2026, 1:08 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Androxal in Male Infertility

NCT02160704
View directory record Official record
Conditions
Infertility
Interventions
Enclomiphene citrate, Placebo
Drug · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 35 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 5, 2026, 1:08 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)

NCT06990906
View directory record Official record
Conditions
Male Infertility, Azoospermia
Interventions
BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
Device · Procedure
Lead sponsor
BAIBYS Fertility
Industry
Eligibility
21 Years to 42 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing the Effect of Abstinence Period on Semen Parameters

NCT05701163
View directory record Official record
Conditions
Infertility, Male
Interventions
Abstinence followed by semen sample collection.
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
20 Years to 45 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 5, 2026, 1:08 AM EDT
Completed Phase 2 Interventional Results available

Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration

NCT01880086
View directory record Official record
Conditions
Hypogonadism, Opioid-Related Disorders, Male Infertility
Interventions
Clomiphene citrate, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Sep 5, 2026, 1:08 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Escitalopram on Sperm DNA Fragmentation

NCT03527043
View directory record Official record
Conditions
Sperm DNA Fragmentation, Infertility, Male
Interventions
Escitalopram, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting No phase listed Observational

Inherited Reproductive Disorders

NCT01500447
View directory record Official record
Conditions
Genetic Disorder, Infertility, Hypogonadism, Amenorrhea
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
6 Weeks to 120 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Completed Phase 2 Interventional

Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer

NCT00080808
View directory record Official record
Conditions
Prostate Cancer
Interventions
Alprostadil (E1), Papaverine, Phentolamine mesylate, Sildenafil citrate, conventional surgery
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Up to 65 Years · Male only
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2012 · Synced Sep 5, 2026, 1:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers

NCT01595308
View directory record Official record
Conditions
Male Infertility
Interventions
Pomegranate juice
Dietary Supplement
Lead sponsor
POM Wonderful LLC
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 13, 2012 · Synced Sep 5, 2026, 1:08 AM EDT
Terminated Phase 2 Interventional Results available

A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

NCT05403476
View directory record Official record
Conditions
Male Idiopathic Infertility
Interventions
FE 999049, Placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
13
States / cities
Tempe, Arizona • San Jose, California • Centennial, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Validation of New Devices Against Ambient Electromagnetic Radiation

NCT04541459
View directory record Official record
Conditions
Male Infertility
Interventions
new device against ambient electromagnetic radiation, sham device against ambient electromagnetic radiation
Device
Lead sponsor
Waveguard GmbH
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 5, 2026, 1:08 AM EDT
Not listed Not applicable Interventional

Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation

NCT04142112
View directory record Official record
Conditions
Infertility, Infertility, Male
Interventions
Ohana IVF Sperm Preparation Kit (OHB035), Standard IVF Preparation Kit (OHB037)
Device
Lead sponsor
Ohana BioSciences
Industry
Eligibility
25 Years to 37 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
7
States / cities
Tempe, Arizona • Clearwater, Florida • Rockville, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Sep 5, 2026, 1:08 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ramipril for the Treatment of Oligospermia

NCT01856361
View directory record Official record
Conditions
Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
Interventions
Ramipril, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting Not applicable Interventional

Platelet Rich Plasma Testis Treatment for Infertile Men

NCT05479474
View directory record Official record
Conditions
Male Infertility, Nonobstructive Azoospermia, Azoospermia
Interventions
Platelet rich plasma
Biological
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting Not applicable Interventional

Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples

NCT04298255
View directory record Official record
Conditions
Infertility, Male
Interventions
Round Spermatid Injection (ROSI), Half ROSI-half Sperm Donor Fertilization
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

GnRH Agonist at Embryo Transfer: IVF Outcomes

NCT03544073
View directory record Official record
Conditions
Infertility, Infertility, Female, Infertility, Male
Interventions
Saline Solution for Injection, Leuprolide Acetate
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 5, 2026, 1:08 AM EDT
Not listed Phase 2 Interventional

Pulsatile GnRH in Anovulatory Infertility

NCT00383656
View directory record Official record
Conditions
Hypogonadotropic Hypogonadism, Amenorrhea, Kallmann's Syndrome
Interventions
GnRH, Pump
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Sep 5, 2026, 1:08 AM EDT
Recruiting Phase 3 Interventional

Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)

NCT05903859
View directory record Official record
Conditions
Infertility, Male
Interventions
Probenecid 500 Milligrams (mg), probenecid 250 Milligrams (mg), Placebo
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 5, 2026, 1:08 AM EDT
Completed No phase listed Observational

Sperm Banking Among Adolescents Newly Diagnosed With Cancer: Development of a Profiling and Referral Tool

NCT01152268
View directory record Official record
Conditions
Cancer
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 21 Years · Male only
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Duarte, California • Los Angeles, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Sep 5, 2026, 1:08 AM EDT