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ClinicalTrials.gov public records Last synced Sep 13, 2026, 4:38 AM EDT

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Showing 1–24 of 93 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Male Infertility Clear all
Completed No phase listed Observational Results available

Retrospective Study on the Use, Efficiency, and Safety of the At-home Mosie Kit

NCT04646291
View directory record Official record
Conditions
Infertility, Infertility, Female, Infertility, Male
Interventions
Insemination with the Mosie Baby Kit
Device
Lead sponsor
Mosie Baby
Industry
Eligibility
Not listed
Enrollment
350 participants
Timeline
2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Sep 13, 2026, 4:38 AM EDT
Recruiting No phase listed Observational

Male Infertility and Assisted Reproductive Technologies Research Biobank

NCT06880302
View directory record Official record
Conditions
Male Infertility, Infertility (IVF Patients)
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
Male only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Phase 2 Interventional Results available

RA-2 13-cis Retinoic Acid (Isotretinoin)

NCT02061384
View directory record Official record
Conditions
Male Infertility, Klinefelter's Syndrome, Y-chromosome Microdeletions
Interventions
13-cis retinoic acid, Calcitriol
Drug
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 60 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 1, 2021 · Synced Sep 13, 2026, 4:38 AM EDT
Active, not recruiting Not applicable Interventional

A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence

NCT07062237
View directory record Official record
Conditions
Infertility, Male Factor Infertility
Interventions
Ultrashort abstinence, Standard abstinence
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 42 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners

NCT00503646
View directory record Official record
Conditions
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
Interventions
communication intervention, counseling intervention, questionnaire administration, psychosocial assessment and care
Other · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2013 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Role of Massage in Increasing Total Motile Sperm Count of IUI

NCT01969825
View directory record Official record
Conditions
Infertility
Interventions
Massage
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 13, 2026, 4:38 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

GnRH Agonist at Embryo Transfer: IVF Outcomes

NCT03544073
View directory record Official record
Conditions
Infertility, Infertility, Female, Infertility, Male
Interventions
Saline Solution for Injection, Leuprolide Acetate
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Choline Dehydrogenase and Sperm Function: Effects of Betaine

NCT02122211
View directory record Official record
Conditions
Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676, Male Infertility
Interventions
Betaine supplement
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Sep 13, 2026, 4:38 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Testicular Evaluation of Azoospermia Using Micro-Ultrasound

NCT06941922
View directory record Official record
Conditions
Azoospermia
Interventions
Not listed
Lead sponsor
Paul Shin
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 13, 2026, 4:38 AM EDT
Completed No phase listed Observational

Regulation of Stem Spermatogonia in the Mature Testis

NCT02756923
View directory record Official record
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Phase 4 Interventional Results available

Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupivacaine

NCT03802864
View directory record Official record
Conditions
Male Infertility
Interventions
Liposomal Bupivacaine, Standard Bupivacaine
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 99 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 13, 2026, 4:38 AM EDT
Terminated No phase listed Observational

Round Spermatid Injection Protocol

NCT04053309
View directory record Official record
Conditions
Male Infertility Due to Azoospermia
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 13, 2026, 4:38 AM EDT
Completed No phase listed Observational

Eeva 12-well Dish Study

NCT01635036
View directory record Official record
Conditions
Infertility
Interventions
In-vitro fertilization using Eeva
Device
Lead sponsor
Progyny, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2014 · Synced Sep 13, 2026, 4:38 AM EDT
Active, not recruiting No phase listed Observational

Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Couples With Non-obstructive Azoospermia (NOA)

NCT06566599
View directory record Official record
Conditions
Non-obstructive Azoospermia, Male Infertility
Interventions
Not listed
Lead sponsor
Inception Fertility Research Institute, LLC
Industry
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Recruiting No phase listed Observational

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

NCT07357701
View directory record Official record
Conditions
Primary Ovarian Insufficiency, Azoospermia, Oligospermia
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 100 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Bethesda, Maryland • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Completed No phase listed Observational

Hormonal Regulation of Puberty and Fertility

NCT01511588
View directory record Official record
Conditions
Endocrine Disease, Infertility, Hypogonadism, Amenorrhea, Adolescents
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
14 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women

NCT00413179
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility, Hyperandrogenism
Interventions
Metformin, Clomiphene citrate, Placebo
Drug
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 40 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2003
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2006 · Synced Sep 13, 2026, 4:38 AM EDT
Recruiting Not applicable Interventional

Testicular Tissue Cryopreservation in Children

NCT02872532
View directory record Official record
Conditions
Cancer, Cancer-Related Condition, Infertility
Interventions
Testicular tissue cryopreservation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
0 Years to 17 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 13, 2026, 4:38 AM EDT
Not yet recruiting Not applicable Interventional

Sperm, Exposure and Endocrine Disruptors

NCT07703046
View directory record Official record
Conditions
Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
Interventions
EDC Education Intervention
Behavioral
Lead sponsor
Million Marker Wellness, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Not applicable Interventional

Effectiveness of the Use of the PICSI Dish (Hyaluronan Microdot) in the Selection of Sperm for Intracytoplasmic Sperm Injection (ICSI)

NCT00741494
View directory record Official record
Conditions
Male Factor Infertility
Interventions
PICSI dish
Device
Lead sponsor
Biocoat
Industry
Eligibility
18 Years to 40 Years
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
9
States / cities
Laguna Hills, California • San Ramon, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2010 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of the Consumer Use of a New Home Test to Measure Sperm Concentration

NCT02475395
View directory record Official record
Conditions
Fertility, Male, Sub-Fertility, Male
Interventions
TRAK device
Device
Lead sponsor
Sandstone Diagnostics
Industry
Eligibility
20 Years to 50 Years
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
3
States / cities
Encino, California • Tarzana, California • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 13, 2026, 4:38 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Androxal in Male Infertility

NCT02160704
View directory record Official record
Conditions
Infertility
Interventions
Enclomiphene citrate, Placebo
Drug · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 35 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 13, 2026, 4:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sperm Selection by Microfluidic Separation Improves Embryo Quality

NCT03085433
View directory record Official record
Conditions
Sperm DNA Fragmentation, Embryo Quality, Fertility Disorders, Infertility, Infertility, Male, Infertility Unexplained
Interventions
Microfluidic Sperm Sorting, in vitro fertilization
Device · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 13, 2026, 4:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele

NCT00044369
View directory record Official record
Conditions
Varicocele, Male Infertility, Hypospermatogenesis, Non-Obstructive Azoospermia
Interventions
Varicocele repair
Procedure
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
2
States / cities
Camden, New Jersey • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2006 · Synced Sep 13, 2026, 4:38 AM EDT