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ClinicalTrials.gov public records Last synced Sep 26, 2026, 10:43 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mammoplasty Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study

NCT01853605
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped silicone gel-filled breast implants
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Sep 26, 2026, 10:43 AM EDT
Not listed No phase listed Observational

The Effects of Indocyanine Green Angiography (IGA) on Deep Inferior Epigastric Artery Perforator (DIEP) Flap Design and Post-Operative Fat Necrosis

NCT02144961
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00691327
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
Female only
Enrollment
84,329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Sep 26, 2026, 10:43 AM EDT
Recruiting Phase 3 Interventional

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

NCT05774678
View directory record Official record
Conditions
Breast Cancer
Interventions
Group 1 (preoperative radiation hypofractionated), Group 2 (preoperative radiation conventionally fractionated)
Radiation · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 26, 2026, 10:43 AM EDT
Not listed No phase listed Observational

Cosmetic Evaluation of Lumpectomy Versus Oncolytic Mammoplasty With Bilateral Breast Reduction for Early Stage Breast Cancer

NCT01400399
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Not listed
Lead sponsor
Coastal Carolina Radiation Oncology
Other
Eligibility
50 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
3
States / cities
Supply, North Carolina • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Sep 26, 2026, 10:43 AM EDT
Completed No phase listed Observational

Development of a Patient Decision Aid for Women Considering Breast Reconstruction

NCT04817709
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Educational Intervention, Usual Care, Media Intervention, Medical Chart Review, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2021 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain in Breast Surgery Intervention

NCT04058938
View directory record Official record
Conditions
Opioid Use, Pain, Postoperative
Interventions
Educational handout instrument, Control
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Sep 26, 2026, 10:43 AM EDT
Terminated Not applicable Interventional Results available

Use of Dermal Matrix in Breast Reconstruction

NCT00692692
View directory record Official record
Conditions
Breast Cancer
Interventions
DermaMatrix, standard of care tissue expander breast reconstruction surgery after mastectomy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced Sep 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BREAST Choice Decision Tool R21 - AIM2

NCT06817226
View directory record Official record
Conditions
Breast Cancer
Interventions
Pre-survey, BREASTChoice tool., Post-survey
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting

NCT00466765
View directory record Official record
Conditions
Mammaplasty, Mastectomy, Lumpectomy
Interventions
Brava Autologous Fat Transfer System
Device
Lead sponsor
Brava
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
589 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Sep 26, 2026, 10:43 AM EDT
Terminated Not applicable Interventional Results available

Fibrin Sealant in Preventing Fluid Build Up During Surgery in Patients Undergoing Breast Reconstruction

NCT01649505
View directory record Official record
Conditions
Breast Cancer, Perioperative/Postoperative Complications
Interventions
fibrin sealant (Beriplast P, TISSEEL VH), breast reconstruction
Drug · Procedure
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Sep 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

NCT04891510
View directory record Official record
Conditions
Mastectomy, Mammaplasty, Breast Reconstruction
Interventions
REVOLVE Advanced Adipose System, LipoGrafter, Viality
Device · Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™

NCT06649890
View directory record Official record
Conditions
Surgical Site Infection, Surgical Complication, Implant Infection, Implant Complication
Interventions
Xperience™ Advanced Surgical Irrigation, Dilute Povidone-Iodine
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction

NCT04777591
View directory record Official record
Conditions
Postoperative Pain, Breast Reconstruction
Interventions
Liposomal bupivacaine TAP block, Bupivacain
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 4 Interventional

The BREASTrial:Breast Reconstruction Evaluation Using Acellular Dermal Matrix as a Sling Trial

NCT00872859
View directory record Official record
Conditions
Breast Cancer, Reconstructive Surgery
Interventions
Implantation of Dermal Matrix substitute
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Sep 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Assessment of the Interi Manifold in Implant-Based Breast Reconstruction

NCT05975359
View directory record Official record
Conditions
Mastectomy, Implant Based Breast Reconstruction
Interventions
Interi Manifold Drain System, Jackson Pratt Drain System
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 3 Interventional

An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries

NCT04785638
View directory record Official record
Conditions
Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy, Colectomy, Reduction Mammoplasty
Interventions
INL-001 (bupivacaine hydrochloride) implant
Combination Product
Lead sponsor
Innocoll
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Florence, Alabama • Sheffield, Alabama • Pasadena, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 26, 2026, 10:43 AM EDT
Completed No phase listed Observational

Retrospective Analysis of Veritas in Breast Reconstruction

NCT01454713
View directory record Official record
Conditions
Seroma, Necrosis, Infection
Interventions
Not listed
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
San Diego, California • Troy, Michigan • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 1 Interventional

Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy

NCT03213249
View directory record Official record
Conditions
Breast Implant Infection, Mammoplasty
Interventions
Normal saline, Cefazolin, Skin biopsy, Bilateral skin- or nipple-sparing mastectomies, Tissue expander, Breast implant, Autologous flap, Acellular dermal matrix sling, Gentamicin, Bacitracin
Other · Drug · Procedure + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Seri Surgical Scaffold Support of the Lower Pole of the Breast

NCT02016612
View directory record Official record
Conditions
Recurrent Ptosis of the Breast
Interventions
Seri Surgical Scaffold
Device
Lead sponsor
Bengtson Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Sep 26, 2026, 10:43 AM EDT
Not listed No phase listed Observational

Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment

NCT01273909
View directory record Official record
Conditions
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Acquired Lymphedema, Congenital Lymphedema
Interventions
Perforator Flap Breast Reconstruction, Vascularized Lymph Node Transfer
Procedure
Lead sponsor
The National Institute of Lymphology
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
3
States / cities
Chicago, Illinois • New Orleans, Louisiana • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2014 · Synced Sep 26, 2026, 10:43 AM EDT
Completed No phase listed Observational

Analysis and Characterization of Biologic Implants

NCT01060046
View directory record Official record
Conditions
Ventral Hernia, Post-mastectomy Breast Reconstruction
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Sep 26, 2026, 10:43 AM EDT
Active, not recruiting No phase listed Observational

A Retrospective Assessment of OviTex PRS (OviTex)

NCT05736848
View directory record Official record
Conditions
Reconstructive Surgical Procedures
Interventions
OviTex® PRS
Device
Lead sponsor
Tela Bio Inc
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
200 participants
Timeline
2022 – 2026
U.S. locations
11
States / cities
Naples, Florida • South Miami, Florida • Alpharetta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient Controlled Tissue Expansion for Breast Reconstruction

NCT01425268
View directory record Official record
Conditions
Breast Cancer
Interventions
AeroForm Tissue Expansion, Saline Tissue Expansion
Device · Procedure
Lead sponsor
AirXpanders, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
17
States / cities
Greenbrae, California • Los Angeles, California • Orange, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 26, 2026, 10:43 AM EDT