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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Manual Therapies Clear all
Completed Not applicable Interventional

Subacute Effects of Spinal Mobilization to Treat Subacromial Impingement

NCT01753271
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
thoracic mobilization & shoulder mobilization & exercise, shoulder mobilization & exercise
Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
3
States / cities
Chicago, Illinois • Elizabethton, Tennessee • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Sep 29, 2026, 8:45 PM EDT
Not listed Phase 2 Interventional

How Does Manual Therapy Improve Low Back Pain for Soldiers?

NCT00394264
View directory record Official record
Conditions
Low Back Pain
Interventions
Soft Tissue, Myofascial release, Counterstrain, Muscle energy, Sacro-iliac articulation, High-velocity, low amplitude
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
17 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Fort Lewis, Washington
Source: ClinicalTrials.gov public record
Updated Oct 30, 2006 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Phase 2 Interventional

Exercise and Manual Therapy for Shoulder Subacromial Impingement Syndrome

NCT00632996
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Rehabilitation
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2015 · Synced Sep 29, 2026, 8:45 PM EDT
Not listed Not applicable Interventional

Effectiveness of Manual Manipulation With EPAT on Ankle Dorsiflexion and Dynamic Plantar Pressure

NCT02233140
View directory record Official record
Conditions
Diabetes, Equinus Contracture of the Ankle
Interventions
Extra-corporeal pulsed-activated therapy or shockwave therapy
Device
Lead sponsor
Temple University
Other
Eligibility
21 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery

NCT05853250
View directory record Official record
Conditions
Coronary Artery Diseases, Valvular Heart Diseases
Interventions
Reiki/manual therapy
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 29, 2026, 8:45 PM EDT
Recruiting Not applicable Interventional

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

NCT06383091
View directory record Official record
Conditions
Total Thyroidectomy
Interventions
Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches, Scar massage, Voice Exercises, Placebo Anterior Neck Manual Therapy, Placebo Pain Neuroscience Education, Placebo Neck Stretches
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 29, 2026, 8:45 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Manual Therapy and Exercise in Shoulder OA

NCT02587559
View directory record Official record
Conditions
Osteoarthritis
Interventions
physical therapy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Integrated Eating Aversion Treatment Manual-Parent Version

NCT02721901
View directory record Official record
Conditions
Feeding and Eating Disorders of Childhood
Interventions
iEAT Manual Intervention, Control group
Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Months to 8 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2017 · Synced Sep 29, 2026, 8:45 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study

NCT07629765
View directory record Official record
Conditions
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Conservative Management of Femoroacetabular Impingement

NCT01814124
View directory record Official record
Conditions
Femoroacetabular Impingement
Interventions
Manual therapy plus exercise, Advice and home exercise
Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

The Use of Manual Therapy to Treat Low-Back and Hip Pain

NCT00410397
View directory record Official record
Conditions
Low Back Pain, Pain
Interventions
Osteopathic Manipulative Medicine, Sham Manipulation
Procedure
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 14, 2008 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome

NCT00633451
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Manual Therapy and Exercise, Exercise Only
Other
Lead sponsor
Proaxis Therapy
Industry
Eligibility
18 Years to 75 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2013 · Synced Sep 29, 2026, 8:45 PM EDT
Not yet recruiting Not applicable Interventional

Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy

NCT07712458
View directory record Official record
Conditions
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Interventions
EMMA (Expert Manipulative Massage Automation)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced Sep 29, 2026, 8:45 PM EDT
Not listed Not applicable Interventional

Manual and Manipulative Therapy for Low Back Pain

NCT00632060
View directory record Official record
Conditions
Low Back Pain
Interventions
Manual / Manipulative Therapy (M/MT)
Procedure
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2008 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia

NCT03167710
View directory record Official record
Conditions
Lateral Epicondylitis
Interventions
Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 60 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cockeysville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Manual Therapy Provide Immediate Improvement in Lumbar Range of Motion?

NCT05926674
View directory record Official record
Conditions
N/A Healthy Individuals
Interventions
Myofascial Release, Light Touch Contact
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 29, 2026, 8:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Mobilization Versus Manipulation on Function in Participants Reporting CAI

NCT03918473
View directory record Official record
Conditions
Ankle Sprains
Interventions
Mobilization with Movement, Thrust Mobilization
Other
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Manual Therapy and Exercise Versus Home Exercises in the Management of Patients Status Post Ankle Sprain

NCT00797368
View directory record Official record
Conditions
Ankle Sprain
Interventions
Manual Therapy and Exercise, Home exercises
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
16 Years to 60 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
Denver, Colorado • Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 8, 2013 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Osteopathic Manual Medicine Treatment in Autism

NCT01676389
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Sham OMM, Osteopathic Manual Medicine (Body Therapy)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
3 Years to 11 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Intervention for Pregnancy Related Pain

NCT03440073
View directory record Official record
Conditions
Other Specified Pregnancy-Related Conditions
Interventions
Mulligan Concept Intervention, Sham Mulligan Concept Treatment
Other
Lead sponsor
University of Idaho
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Piano Therapy vs. Piano Listening on Manual Dexterity in the Elderly

NCT03372031
View directory record Official record
Conditions
Aging, Manual Dexterity, Piano Therapy
Interventions
Piano training (Active), Piano Training (Passive)
Behavioral
Lead sponsor
Westminster College
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Wilmington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Sep 29, 2026, 8:45 PM EDT
Recruiting Phase 2 Interventional

A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

NCT06327490
View directory record Official record
Conditions
Breast Cancer
Interventions
ICG-guided manual lymphatic drainage, Traditional manual lymphatic drainage, Indocyanine green
Procedure · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 29, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder

NCT00106223
View directory record Official record
Conditions
Body Dysmorphic Disorder, Somatoform Disorders
Interventions
Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Charlestown, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 29, 2026, 8:45 PM EDT