Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 22, 2026, 1:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Manual Therapy Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of Strain-counterstrain on Ankle Instability

NCT02025569
View directory record Official record
Conditions
Other Instability, Ankle and Foot
Interventions
Strain Counterstrain, Sham strain counterstrain
Other
Lead sponsor
Long Island University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2013 · Synced Sep 22, 2026, 1:51 PM EDT
Enrolling by invitation Not applicable Interventional

Percussive vs. Gentle Massage for Recovery After Hip Replacement

NCT07790705
View directory record Official record
Conditions
Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
Interventions
Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
Device · Other
Lead sponsor
Zachary M Ricciardelli
Network
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cumming, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Active, not recruiting Not applicable Interventional Results available

Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors

NCT03612531
View directory record Official record
Conditions
Cancer Survivor, Dysphagia, Fibrosis, Head and Neck Carcinoma
Interventions
Manual Therapy
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study

NCT07629765
View directory record Official record
Conditions
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Recruiting Not applicable Interventional

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

NCT06297265
View directory record Official record
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Localized Breast Carcinoma
Interventions
Lymphedema Management, Questionnaire Administration, Adjuvant breast radiation therapy
Other · Radiation
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

NCT01188837
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Full Kinetic Chain Manipulative Therapy, Full Kinetic Chain Rehabilitation, Full Kinetic Chain Manipulative Therapy with Rehabilitation
Other
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
38 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Piano Therapy vs. Piano Listening on Manual Dexterity in the Elderly

NCT03372031
View directory record Official record
Conditions
Aging, Manual Dexterity, Piano Therapy
Interventions
Piano training (Active), Piano Training (Passive)
Behavioral
Lead sponsor
Westminster College
Other
Eligibility
70 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Wilmington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Sep 22, 2026, 1:51 PM EDT
Not listed Not applicable Interventional

Cervical-Cranial Dry Needling vs. Orthopedic Manual Therapy for Cervicogenic Headache

NCT03583190
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Cervical-cranial dry needling, Orthopedic manual therapy, Thoracic Manipulation, Exercise, Patient Education
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Combined Effects of Manual Therapy on the Shoulder

NCT04777370
View directory record Official record
Conditions
Range of Motion, Manual Therapies, Shoulder Joint Disorder
Interventions
posterior glide mobilization, Sleeper stretch, thoracic manipulation
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Phase 2Phase 3 Interventional

Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial

NCT01571674
View directory record Official record
Conditions
Shoulder Pain
Interventions
Manipulation + Exercise Group, Exercise Group
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
9
States / cities
Aurora, Colorado • Boulder, Colorado • Concord, New Hampshire + 5 more
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study

NCT06841627
View directory record Official record
Conditions
Primary Headaches (Migraines, Tension, Cluster Headaches)
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Recruiting Not applicable Interventional

Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain

NCT07278570
View directory record Official record
Conditions
Myofascial Pain Syndrome - Lower Back, Myofascial Pain
Interventions
Tuina treatment, Usual care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Structural Integration for Chronic Low Back Pain

NCT01322399
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Structural Integration, Usual care
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Sep 22, 2026, 1:51 PM EDT
Recruiting Phase 2 Interventional

A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

NCT06327490
View directory record Official record
Conditions
Breast Cancer
Interventions
ICG-guided manual lymphatic drainage, Traditional manual lymphatic drainage, Indocyanine green
Procedure · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 22, 2026, 1:51 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Mobilization Versus Manipulation on Function in Participants Reporting CAI

NCT03918473
View directory record Official record
Conditions
Ankle Sprains
Interventions
Mobilization with Movement, Thrust Mobilization
Other
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Manual Medicine or Cognitive Behavioral Therapy With Chronic Uncontrolled Diabetes

NCT02971865
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
CBT/CMT, Control group traditional primary care
Behavioral · Other
Lead sponsor
Community Wellness Center, West Linn, OR
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
West Linn, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain

NCT02060617
View directory record Official record
Conditions
Low Back Pain
Interventions
Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises, Treatment-Based Classification intervention
Behavioral · Procedure
Lead sponsor
Hendricks Regional Health
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Plainfield, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders

NCT03959319
View directory record Official record
Conditions
Hip-related Groin Pain, Femoroacetabular Impingement, Dysplasia Mild, Prearthritic Hip Disorder
Interventions
Movement Pattern Training, Manual Therapy
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Thoracic Mobilization on Shoulder Range of Motion

NCT01518504
View directory record Official record
Conditions
Shoulder Range of Motion in Healthy Individuals
Interventions
Thoracic Mobilization, Sham
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 20, 2012 · Synced Sep 22, 2026, 1:51 PM EDT
Not listed No phase listed Observational

Applying Pain Adaptability to Manual Therapy Practice

NCT05209659
View directory record Official record
Conditions
Musculoskeletal Manipulations, Low Back Pain
Interventions
Pragmatic Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Haslett, Michigan • Old Bridge, New Jersey • Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

NCT01318720
View directory record Official record
Conditions
Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Masefield and Cavallaro Physical Therapy
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 22, 2026, 1:51 PM EDT
Completed Not applicable Interventional

Epidural Steroid Injection Versus Epidural Steroid Injection and Manual Physical Therapy and Exercise in the Management of Lumbar Spinal Stenosis

NCT00786981
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Epidural steroid injection plus physical therapy, Epidural steroid injection
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
50 Years to 90 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
4
States / cities
Denver, Colorado • Peoria, Illinois • Keesler Air Force Base, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 22, 2026, 1:51 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Manual Therapy and Exercise in Shoulder OA

NCT02587559
View directory record Official record
Conditions
Osteoarthritis
Interventions
physical therapy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 22, 2026, 1:51 PM EDT
Enrolling by invitation Not applicable Interventional

Automated Manual Lymphatic Drainage Therapy to Improve Glymphatic Function in OSA Patients

NCT07301762
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), OSA, Obstructive Sleep Apnea
Interventions
Automated manual lymphatic drainage therapy (AMLDT) device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 22, 2026, 1:51 PM EDT