Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:44 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 66 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Margins of Excision Clear all

Conditions: Prostate Cancer
Interventions: Not listed
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Male only
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Mucopolysaccharidosis (MPS), Hunter Syndrome
Interventions: Not listed
Lead sponsor: Shire; Industry
Eligibility: 2 Years to 18 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 3
States / cities: Oakland, California • Chicago, Illinois • Chapel Hill, North Carolina

Conditions: Oropharyngeal Cancer
Interventions: TraceIT Tissue Marker; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cutaneous Melanoma by AJCC V7 Stage
Interventions: Wide Local Excision = 1cm Margin, Wide Local Excision = 2cm Margin; Procedure
Lead sponsor: Melanoma and Skin Cancer Trials Limited; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Basal Cell Carcinoma
Interventions: Two photon microscopy imaging; Device
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Victor, New York

Conditions: Type 1 Diabetes
Interventions: Care Ambassador Intervention, Psychoeducational Intervention; Behavioral
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 8 Years to 16 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Malignant Melanoma
Interventions: Wide Local Excision; Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Breast Cancer, Cancer of Breast, Cancer of the Breast
Interventions: Breast-conserving surgery (BCS), Cavity shave margins (CSM), BREAST-Q Questionnaire, 3-D breast imaging, Indocyanine green, Intraoperative imaging device, Peripheral blood draw; Procedure · Behavioral · Device + 1 more
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Soft Tissue Sarcoma (STS)
Interventions: 5-ALA; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Breast Cancer
Interventions: MarginProbe; Device
Lead sponsor: Huntington Memorial Hospital; Other
Eligibility: Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pasadena, California

Conditions: Dysplastic Nevi
Interventions: Saucerization biopsy; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Oropharyngeal Cancer
Interventions: TORS, Adjuvant Radiation Therapy; Procedure · Radiation
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Carcinoma, Adenocarcinoma, Renal Cell, Nephroid Carcinoma, Hypernephroid
Interventions: RAD001(everolimus), interferon alfa-2a, bevacizumab; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 365 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 9
States / cities: Fayetteville, Arkansas • Duarte, California • Los Angeles, California + 5 more

Conditions: Breast Neoplasms, Breast Cancer, Breast Tumors, Cancer of Breast, Cancer of the Breast, Human Mammary Carcinoma, Neoplasms, Breast
Interventions: Remove tumor only, Removal of tumor and tissue; Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: BCC - Basal Cell Carcinoma, BCC, Excision Margin
Interventions: CellFX System; Device
Lead sponsor: Pulse Biosciences, Inc.; Industry
Eligibility: 22 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 5
States / cities: Vestavia Hills, Alabama • Beverly Hills, California • Clearwater, Florida + 2 more

Conditions: Breast Cancer
Interventions: miniature spectral imaging system, Bench-top optical spectrometer, High resolution microendoscope; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Durham, North Carolina • Madison, Wisconsin

Conditions: Cutaneous Melanoma, Stage II, Cutaneous Melanoma, Acral Melanoma
Interventions: Wide Local Excision; Diagnostic Test
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 282 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Prostate Cancer
Interventions: Histolog Scan; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Male only
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Malignant Neoplasm
Interventions: Indocyanine green (ICG); Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Breast Cancer
Interventions: ClearEdge device; Device
Lead sponsor: LS BioPath; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Prostate Cancer
Interventions: Not listed
Lead sponsor: U.S. Army Medical Research Acquisition Activity; Federal
Eligibility: 40 Years and older · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Breast Cancer
Interventions: fluorescence spectroscopy and diffuse spectroscopy; Procedure
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Breast Cancer
Interventions: Radiofrequency Ablation; Device
Lead sponsor: University of Arkansas; Other
Eligibility: 50 Years to 100 Years · Female only
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2027
U.S. locations: 6
States / cities: Tucson, Arizona • Little Rock, Arkansas • San Diego, California + 3 more

Conditions: Breast Cancer
Interventions: 49-channel optical spectrometer; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 485 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

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Retrospective Study of Positive Biopsy Specimens on Patients Undergoing a Prostatectomy

Observational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II)

TraceIT Tissue Marker to Mark the Primary Resection Bed Margins of Oropharyngeal Cancers

MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma

Investigation of Mohs Surgical Margins Using Two Photon Microscopy

Intensive Care Program for Youth With Diabetes

Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 Melanoma

Shave Margins in Breast Conservation Therapy

5-AminoLevulinic Acid Aided Resection Margins in Sarcoma

Study of the Outcomes of Intraoperative Margin Assessment With MarginProbe

Prospective Study of 2 mm Margins for the Biopsy of Dysplastic Nevi

A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer

Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney Cancer

Evaluating and Comparing Two Surgical Methods for Treatment of Early Stage Breast Cancer

CellFX Treat & Resect Low-Risk BCC Feasibility Study

A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins

Trial Comparing CPDMA Versus Standard Breadloafing in WLE Specimens of Stage 1-II Cutaneous Melanoma

Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen

Potential Use of Indocyanine Green as a Fluorescent Agent for Definition of Surgical Margins in Cancer

Intraoperative Use of ClearEdge Device in Breast Conserving Surgery

Reduced Planning Target Volume (PTV) Margins for the Treatment of Prostate Cancer Using the Calypso 4D Localization System

Evaluation of Breast Cancer Surgical Margins Using Optical Spectroscopy

Excision Followed by Radiofrequency Ablation for Breast Cancer

An Optical Assay System for Intra Operative Assessment of Tumor Margins in Patients