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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Marijuana Smoking Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Dronabinol (Oral THC) on Cannabis Use

NCT01394185
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Dronabinol 120mg/day, Placebo, Dronabinol 240mg/day
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Sep 26, 2026, 9:34 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on E-Cigarette Use Behavior

NCT06609109
View directory record Official record
Conditions
Cannabis Use, Tobacco Use, Electronic Cigarette Use
Interventions
THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents (smokeScreen)

NCT03722888
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN video game
Device
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
3
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Sep 26, 2026, 9:34 AM EDT
Completed No phase listed Observational

Consequences of Marijuana Use in HIV-infected Youth

NCT03927053
View directory record Official record
Conditions
Youth With HIV
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
21 Years to 28 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 26, 2026, 9:34 AM EDT
Completed No phase listed Observational Results available

Feasibility and Validation of a Standard Phenotyping Assessment Battery

NCT03495869
View directory record Official record
Conditions
Opioid-use Disorder, Cocaine Use Disorder, Marijuana Use Disorder, Healthy Controls
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 70 Years
Enrollment
368 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Phase 2 Interventional Results available

A Trial of N-Acetylcysteine (an Over-the-Counter Medicine) in Adolescents Who Smoke Marijuana

NCT01005810
View directory record Official record
Conditions
Cannabis Dependence
Interventions
N-Acetylcysteine, placebo, Contingency Management
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 21 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional

An Exercise App to Reduce Young Adults' MJ Use

NCT01863095
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Personalized Feedback and Exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2016 · Synced Sep 26, 2026, 9:34 AM EDT
Recruiting Phase 3 Interventional

Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder

NCT07644052
View directory record Official record
Conditions
Cannabis Withdrawal
Interventions
PP-01, Nabilone, Placebo
Combination Product · Drug
Lead sponsor
PleoPharma, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
22
States / cities
Little Rock, Arkansas • Rogers, Arkansas • New Haven, Connecticut + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 26, 2026, 9:34 AM EDT
Recruiting Not applicable Interventional

Neuroimaging of Adolescent Cannabis Use Treatment

NCT07340554
View directory record Official record
Conditions
Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse, Cannabis Intoxication, Cannabis Smoking, Cannabis Withdrawal, Cannabis-Related Disorder, Cannabis Abuse, in Remission, Cannabis Abuse, Episodic Use, Marijuana, Marijuana Abuse, Marijuana Use, Marijuana Smoking, Marijuana Dependence, Marijuana User, Marijuana-Related Disorder, Marijuana Use Disorder, Addiction, Addiction, Substance, Substance Use, Substance Use Disorders, Substance Dependence, Substance Abuse, Substance Related Problem, Substance Abuse Drug Chronic
Interventions
Contingency Management, Elastic Net Regression
Behavioral · Device
Lead sponsor
Indiana University
Other
Eligibility
14 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Results available

Mobile Contingency Management for Marijuana and Tobacco Cessation

NCT02869451
View directory record Official record
Conditions
Cigarette Smoking, Marijuana Abuse
Interventions
bupropion, transdermal nicotine patch, Nicotine polacrilex, nicotine lozenge, counseling for marijuana and smoking cessation, mobile contingency management
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Sep 26, 2026, 9:34 AM EDT
Completed No phase listed Observational

Medical Marijuana Use in HIV+ Patients: Probability Survey

NCT01536912
View directory record Official record
Conditions
HIV Positive
Interventions
Not listed
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 29, 2015 · Synced Sep 26, 2026, 9:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening Protocol for Research Participants

NCT01010620
View directory record Official record
Conditions
Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
Interventions
Various Screening psychiatric and medical assessments
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2019
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2019 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents

NCT03107936
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use

NCT03401333
View directory record Official record
Conditions
Alcohol Drinking, Marijuana
Interventions
Text Messaging and Brief Negotiation Interview
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Mediated Versus Face-to-Face Motivational-Type Interviews

NCT06945471
View directory record Official record
Conditions
Marijuana Use
Interventions
1) Face-to-face, and 2) Computer-mediated motivational type interviews
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 29 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 26, 2026, 9:34 AM EDT
Completed No phase listed Observational

Questionnaires in Assessing Attitudes About Legalization of Marijuana Use in Participants With Cancer

NCT03360799
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Gilbert, Arizona • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents

NCT04707911
View directory record Official record
Conditions
Vaping
Interventions
Social Media Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 21 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment for Adolescent Marijuana Abuse

NCT00580671
View directory record Official record
Conditions
Marijuana Abuse
Interventions
MET/CBT, CM, BPT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Sep 26, 2026, 9:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults

NCT07398443
View directory record Official record
Conditions
Behavioral Economics, Cannabis Smoking, Tobacco Smoking
Interventions
Cue Reactivity
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 25 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Vaping THC From Electronic Cigarettes

NCT02955329
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Nicotine, Cannabis, PAX Loose Leaf Vaporizer
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Behavioral Economic Analysis of Demand for Marijuana

NCT03518567
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Smoked marijuana cigarettes: High THC dose (6% THC)
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 50 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 11, 2024 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco

NCT04737772
View directory record Official record
Conditions
Smoking Cessation, Marijuana Use
Interventions
Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
21 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Not applicable Interventional Results available

Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy

NCT02191605
View directory record Official record
Conditions
Marijuana Use, Pregnancy
Interventions
eSBIRT, Tailored texting
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Sep 26, 2026, 9:34 AM EDT
Completed Phase 2 Interventional Results available

Laboratory Study of Cannabidiol on the Effects of Smoked Marijuana

NCT01844687
View directory record Official record
Conditions
Smoking, Marijuana
Interventions
CBD
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Lexington, Kentucky • New York, New York • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Sep 26, 2026, 9:34 AM EDT