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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:56 PM EDT

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Showing 289–312 of 339 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Marijuana Use Clear all
Recruiting Phase 1 Interventional Accepts healthy volunteers

Cannabis and Opioid Use Disorder

NCT05729932
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Inhaled vaporized cannabis, Intransal opioid
Drug
Lead sponsor
Shanna Babalonis, PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Not applicable Interventional Results available

First Episode Schizophrenia and Cannabis-Related Disorder Study

NCT00573287
View directory record Official record
Conditions
Cannabis-Related Disorder, Substance-Related Disorders, Schizophrenia, Psychotic Disorders
Interventions
clozapine, risperidone
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
17 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
5
States / cities
Concord, New Hampshire • Lebanon, New Hampshire • Manchester, New Hampshire + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effects of ∆-9-THC and Naloxone in Humans

NCT01591629
View directory record Official record
Conditions
Healthy
Interventions
Naloxone, Delta-9-THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study

NCT05380583
View directory record Official record
Conditions
Psychosis, Substance Use, Substance Use Disorders, Family, Cannabis, Marijuana, Alcohol, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Mental Disorder
Interventions
CRAFT-EP, TAU
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed No phase listed Observational Results available

Feasibility and Validation of a Standard Phenotyping Assessment Battery

NCT03495869
View directory record Official record
Conditions
Opioid-use Disorder, Cocaine Use Disorder, Marijuana Use Disorder, Healthy Controls
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 70 Years
Enrollment
368 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 22, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

Cannabis Reduction and Functional Outcomes

NCT07218471
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
CBT4CBT (Computerized Cognitive Behavioral Therapy), Motivational Interviewing, Contingency Management
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Not listed Not applicable Interventional

Breathwork-assisted Treatment for Cannabis Use Disorder

NCT05219825
View directory record Official record
Conditions
Addiction, Substance Abuse, Cannabis Use Disorder, Cannabis Use, Cannabis Dependence, Cannabis Abuse
Interventions
Breathwork workshop
Behavioral
Lead sponsor
Elias Dakwar
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 4:56 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis

NCT05664763
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
[18F]FPEB with PET, Cannabis abstinence
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Phase 2 Interventional Results available

Gabapentin for Bipolar & Cannabis Use Disorders

NCT03334721
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar II Disorder, Cannabis Use Disorder, Substance Use Disorders
Interventions
Gabapentin, Placebo Oral Capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court

NCT01403298
View directory record Official record
Conditions
HIV/AIDS
Interventions
Family-Based HIV prevention, Adolescent Only Health Promotion
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 22, 2026, 4:56 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Research Investigating Drug Effects-2 (RiDE-2)

NCT06758596
View directory record Official record
Conditions
Cannabis Use, Substance Use Disorder (SUD), Healthy
Interventions
Placebo Oral Capsule, THC
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 21 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Behavioral Pharmacology of THC and Beta-Myrcene

NCT05432284
View directory record Official record
Conditions
Cannabis Use
Interventions
Placebo, THC, Beta-Myrcene
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

NCT06077292
View directory record Official record
Conditions
Cannabis Use, THC, Marijuana Use, Cognitive Impairment, THC Vaping
Interventions
15% THC Potency Reduction, 35% THC Potency Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 25 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Phase 2 Interventional Results available

Buspirone, Stress, and Attentional Bias to Marijuana Cues

NCT02132832
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Buspirone, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 22, 2026, 4:56 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

NCT07225738
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Non-Interventional Study
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
11
States / cities
Goodyear, Arizona • Duarte, California • Huntington Beach, California + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Impact of Cannabis Use and Abstinence on Emotion

NCT07746440
View directory record Official record
Conditions
Cannabis Use Disorder, Severe
Interventions
Contingency management for cannabis abstinence and lab visit attendance, Contingency management for lab visit attendance
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Recruiting Phase 2 Interventional

Endocannabinoids in Reward

NCT07815691
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 45 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Phase 1 Interventional Results available

Facilitating the Behavioral Treatment of Cannabis Use Disorder

NCT02946489
View directory record Official record
Conditions
Cannabis Dependence
Interventions
CI-581a
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 22, 2026, 4:56 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With Schizophrenia

NCT01598896
View directory record Official record
Conditions
Cannabis Dependence, Marijuana Dependence
Interventions
Dronabinol, Clonidine, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2018 · Synced Oct 22, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

Cannabis, Linked Emotions, and Adolescent Risk Study

NCT06576076
View directory record Official record
Conditions
Cannabis Use, Depression, Suicidal Ideation, Adolescent Behavior
Interventions
Contingency management for cannabis abstinence
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Phase 2 Interventional Results available

Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence

NCT01292642
View directory record Official record
Conditions
Cannabis Dependence, Nicotine Dependence
Interventions
Cognitive Behavioral Therapy, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2013 · Synced Oct 22, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

NCT06878859
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Cannabis Use Disorder, Mental Disorder
Interventions
Amplification of Positivity - Cannabis Use (AMP-C)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Medications Development for the Treatment of Cannabis Related Disorders

NCT01204723
View directory record Official record
Conditions
Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence, Cannabis Abuse
Interventions
Placebo Aprepitant, Active Aprepitant
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 45 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2012 · Synced Oct 22, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Medical Marijuana on Neurocognition and Escalation of Use

NCT03224468
View directory record Official record
Conditions
Pain, Insomnia, Depression, Anxiety
Interventions
Medical Marijuana
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2023 · Synced Oct 22, 2026, 4:56 PM EDT