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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 88 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Mastectomy and Breast Reconstruction Clear all

Conditions: Breast Cancer, Breast Reconstruction, Cosmesis
Interventions: Nipple Sparing Mastectomy; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2018
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Malignant Breast Neoplasm
Interventions: Ultrasonography, Automated Breast Ultrasound; Procedure
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Breast Cancer
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 25 Years to 65 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Mastectomy
Interventions: Discharge timing; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 19 Years to 80 Years · Female only
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Other Reconstructive Surgery
Interventions: Sham PEMF Device, Ivivi Torino II PEMF Device; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer
Interventions: Meso BioMatrix Device; Device
Lead sponsor: Kensey Nash Corporation; Industry
Eligibility: 21 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 6
States / cities: Detroit, Michigan • Garden City, New York • Bala-Cynwyd, Pennsylvania + 2 more

Conditions: Breast Cancer
Interventions: Delayed Breast Reconstruction; Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Cancer, Ductal Carcinoma
Interventions: Nipple-Sparing Mastectomy, Breast Reconstruction, Axillary Surgery, Prophylactic Nipple-Areolar Complex RT; Procedure · Radiation
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older · Female only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Mastectomy, Postoperative Pain, Complications
Interventions: Dermamatrix to cover lateral aspect of tissue expander, Serratus anterior to cover lateral aspect of tissue expander; Procedure
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Breast Cancer Female
Interventions: Not listed
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 575 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2030
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Breast Cancer
Interventions: Alloderm, Surgimend; Device
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Cancer
Interventions: Tranexamic Acid, Saline; Drug · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Breast Cancer Female
Interventions: Bupivacaine Hydrochloride, Placebo Drug, Pulsed Electromagnetic Field (PEMF) Device, Placebo Device, Ropivacaine Hydrochloride; Drug · Other · Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer, Breast Cancer Female
Interventions: PVB Protocol, PECS-1, Serratus; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,507 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-Mastectomy Chronic Pain Syndrome (Disorder)
Interventions: Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection; Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Ductal Breast Carcinoma, Invasive Breast Carcinoma, Lobular Breast Carcinoma, Medullary Breast Carcinoma, Stage II Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage IIIA Breast Cancer, Tubular Breast Carcinoma
Interventions: Radiation Therapy, Questionnaire Administration, Quality-of-Life Assessment, Laboratory Biomarker Analysis, Hypofractionated Radiation Therapy; Radiation · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 898 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2035
U.S. locations: 846
States / cities: Anchorage, Alaska • Fairbanks, Alaska • Kingman, Arizona + 544 more

Conditions: Pre-Pectoral Breast Reconstruction Following Mastectomy
Interventions: AlloMend® Acellular Dermal Matrix allograft; Other
Lead sponsor: AlloSource; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Reno, Nevada

Conditions: Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection, Surgical Site Infection, Breast Cancer, Mastectomy; Lymphedema
Interventions: Impact Advanced Recovery; Dietary Supplement
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Breast Cancer
Interventions: LTM - a porcine-based surgical mesh; Device
Lead sponsor: LifeCell; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • Chicago, Illinois • Great Neck, New York + 2 more

Conditions: Mammaplasty, Mastectomy, Lumpectomy
Interventions: Brava Autologous Fat Transfer System; Device
Lead sponsor: Brava; Industry
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 589 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Interventions: AlloMend® Acellular Dermal Matrix allograft; Other
Lead sponsor: AlloSource; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Joliet, Illinois

Conditions: Breast Reconstruction
Interventions: ARTIA Reconstructive Tissue Matrix; Device
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 264 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2031
U.S. locations: 23
States / cities: Los Angeles, California • Orange, California • Palo Alto, California + 20 more

Conditions: Pain
Interventions: Bupivacaine, Saline; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 100 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain, Postoperative
Interventions: Liposomal bupivacaine right injection, Liposomal bupivacaine left injection; Drug
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Greenville, South Carolina

Search by objective public record fields.

Nipple Sparing Mastectomy - Cosmetic Outcomes

A Study to Compare the Effectiveness of Two Types of Ultrasound Technologies in Women Who Have Had Breast Cancer

The Effects of Indocyanine Green Angiography (IGA) on Deep Inferior Epigastric Artery Perforator (DIEP) Flap Design and Post-Operative Fat Necrosis

RCT Implant Based Breast Reconstruction

Use of Pulsed Electromagnetic Fields (PEMF) After Breast Reconstruction Surgery

Feasibility Study of Meso BioMatrix Device for Breast Reconstruction

Delayed-Delayed Breast Reconstruction

Nipple-Areola Complex (NAC) Irradiation After Nipple-Sparing Mastectomy and Reconstruction

The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction

Assessment of Breast Cancer Patients Satisfaction and Health Related Quality of Life Outcomes

Bioprosthetic Mesh to Expand the Lower Pole in Tissue Expander Reconstruction

Impact of Topical Tranexamic Acid in Breast Reconstruction

PEMF and PEC Blocks in Mastectomy Reconstruction Patients

Study of Nerve Block Pain Management in Patients Undergoing a Double Mastectomy With Immediate Reconstruction

Cryoablation for Post Mastectomy Pain Syndrome

Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

Retrospective Study of AlloMend Acellular Dermal Matrix (ADM) Allograft and Pre-Pectoral Breast Reconstruction

Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction

Immediate Postmastectomy Breast Reconstruction (Strattice Breast)

Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting

AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain

Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery