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Showing 1–24 of 176 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Maternal; Procedure Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Small Moments Big Impact (SMBI)

NCT03887832
View directory record Official record
Conditions
Empathy
Interventions
SMBI digital app, media package, standard newborn and infant care
Other · Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Jul 21, 2026, 11:03 AM EDT
Completed No phase listed Observational

Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention

NCT06067126
View directory record Official record
Conditions
Overweight, Obese, Metabolic Disorders, Postpartum
Interventions
Not listed
Lead sponsor
Kaiser Permanente
Other
Eligibility
Female only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Interventions to Reduce Excess Weight Gain in Pregnancy

NCT01643356
View directory record Official record
Conditions
Overweight and Obesity, Pregnancy
Interventions
Intervention to reduce excess weight gain during pregnancy
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Health Diabetes Prevention Study

NCT05343494
View directory record Official record
Conditions
Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention

NCT01236248
View directory record Official record
Conditions
Substance Use
Interventions
Prevention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
11 Years to 13 Years · Female only
Enrollment
916 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment, Feedback, Incentive, Exchange (AFIX OB) A Customizable Quality Improvement Intervention to Increase Maternal Vaccine Uptake

NCT04678271
View directory record Official record
Conditions
Influenza, Whooping Cough
Interventions
AFIX-OB Quality Improvement Package
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Smartphone Intervention for WIC Mothers to Improve Nutrition and Weight Gain During Pregnancy

NCT04028843
View directory record Official record
Conditions
Weight Gain During Pregnancy
Interventions
Healthy Beginnings
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 21, 2026, 11:03 AM EDT
Enrolling by invitation No phase listed Observational

Physical Acvitiy in Pregnancy

NCT07356180
View directory record Official record
Conditions
Pregnant Women, Gestational Diabetes, Obese But Otherwise Healthy Participants, Overweight (BMI > 25), Gestational Diabetes Mellitus in Pregnancy
Interventions
Pregnancy Physical Activity Questionnaire (PPAQ)
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)

NCT00951717
View directory record Official record
Conditions
Depression, Postpartum, Depression
Interventions
Behavioral education intervention
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
590 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2011 · Synced Jul 21, 2026, 11:03 AM EDT
Not yet recruiting Not applicable Interventional

Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

NCT07582861
View directory record Official record
Conditions
Congenital Heart Disease (CHD)
Interventions
HeartGPS
Other
Lead sponsor
Carelon Research
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
17
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Completed No phase listed Observational

Follow-up Study of Late Effects of Periconceptional Folic Acid in Mothers and Offspring in the Community Intervention Program Population: The Chinese Children and Families Study

NCT01365975
View directory record Official record
Conditions
Pediatric Leukemia, Other Pediatric Cancers
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
15 Years to 60 Years
Enrollment
1,382 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Mothers-Healthy Children Nutrition

NCT03866902
View directory record Official record
Conditions
Overweight and Obesity, Adiposity, Nutrient; Excess, Physical Activity
Interventions
Nutrition and Physical Activity Intervention, English for Second Language Intervention
Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
3 Years to 50 Years
Enrollment
578 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Not yet recruiting Not applicable Interventional

Pilot Feasibility Study With Doulas

NCT07614789
View directory record Official record
Conditions
Post Partum, Maternal Depression, Maternal Depression and Parent Practices, Postpartum
Interventions
YouMatter
Behavioral
Lead sponsor
Duke University
Other
Eligibility
Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Phase 2 Interventional

Relational Parenting Group for Opioid-addicted Mothers

NCT00319241
View directory record Official record
Conditions
Substance Abuse, Child Abuse
Interventions
Parenting Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Mother-Infant Intervention for Postpartum Depression and Associated Mother-Infant Relationship Dysfunction

NCT02057627
View directory record Official record
Conditions
Postpartum Depression
Interventions
Perinatal Dyadic Psychotherapy, Placebo Comparator
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Nurture: A Program for Mothers With Histories of Disordered Eating

NCT00877994
View directory record Official record
Conditions
Eating Disorders
Interventions
Nurture Support Group Therapy, Group therapy
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Jul 21, 2026, 11:03 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Mama Empoderada: Parenting and Mental Health Intervention

NCT07569393
View directory record Official record
Conditions
Parenting, Mental Health
Interventions
Mama Empoderada
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Finances First: A Health Intervention in Low Income Single Mother Households

NCT03035240
View directory record Official record
Conditions
Financial Stress
Interventions
Financial Education
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 55 Years · Female only
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Integrated Intervention for Caregivers--Pilot RCT

NCT03487627
View directory record Official record
Conditions
Distress; Maternal, Self Efficacy, Parenting, Suicide
Interventions
Electronic and Care Support Manager Contact, Enhanced Treatment-as-usual (TAU)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 29, 2022 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

Child Healthcare at MATER - Pediatric Study

NCT05488379
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Group well child care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 21, 2026, 11:03 AM EDT
Completed Not applicable Interventional

A RCT of CenteringPregnancy on Birth Outcomes and Maternal Inflammation

NCT04097548
View directory record Official record
Conditions
Preterm Birth
Interventions
CenteringPregnancy
Behavioral
Lead sponsor
Endeavor Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 21, 2026, 11:03 AM EDT
Not listed Not applicable Interventional

A Scaleable Video Coaching Intervention for Opioid-using Mothers

NCT04749771
View directory record Official record
Conditions
Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
Interventions
Filming Interactions to Nurture Development, The Healthy Toddler Program
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Up to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Jul 21, 2026, 11:03 AM EDT
Enrolling by invitation Not applicable Interventional

The Maternal Health Multilevel Intervention for Racial Equity (MIRACLE) Project

NCT05386316
View directory record Official record
Conditions
Maternal Morbidity and Mortality, Health Disparities
Interventions
Multilevel intervention for racial disparities in severe maternal morbidity and mortality, Standard Enhanced Prenatal Care (EPC) services
Other
Lead sponsor
Michigan State University
Other
Eligibility
Female only
Enrollment
540,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jul 21, 2026, 11:03 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers

NCT06520696
View directory record Official record
Conditions
Breastfeeding, Exclusive
Interventions
MILC application, Usual care
Behavioral
Lead sponsor
Benten Technologies, Inc.
Industry
Eligibility
18 Years to 44 Years · Female only
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Farmington, Connecticut • Research Triangle Park, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Jul 21, 2026, 11:03 AM EDT