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ClinicalTrials.gov public records Last synced Sep 30, 2026, 4:56 PM EDT

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Showing 25–47 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Maternal Anxiety Clear all
Completed Phase 2 Interventional Results available

Inhaled Oxytocin and HPA Axis Reactivity

NCT03593473
View directory record Official record
Conditions
Depression, Postpartum, Anxiety Disorders, Stress, Psychological
Interventions
Intranasal Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Sep 30, 2026, 4:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The DC Mother-Infant Behavioral Wellness Program

NCT05345834
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety, Prenatal Stress
Interventions
Patient Navigation, Adapted Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Sep 30, 2026, 4:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Maternal Well-Being Study

NCT05484999
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
Interventions
Meals, Meals + Social Support, Control
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 30, 2026, 4:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

NCT02158338
View directory record Official record
Conditions
Asthma in Children, Anxiety
Interventions
Asthma, Non-asthma
Other
Lead sponsor
Ran Anbar
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 30, 2026, 4:56 PM EDT
Not yet recruiting Not applicable Interventional

Debriefing Consult for Psychiatric Symptoms After Severe Maternal Morbidity

NCT07684521
View directory record Official record
Conditions
PTSD (Childbirth-Related), Severe Maternal Morbidity, Depression - Major Depressive Disorder, Anxiety
Interventions
Virtual maternal fetal medicine debriefing consult
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Heart Rate Variability Biofeedback With In-patient Pregnant Women

NCT02119936
View directory record Official record
Conditions
Maternal Stress, Maternal Anxiety, Maternal Health Services
Interventions
Heart Rate Variability Biofeedback Tool
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680
View directory record Official record
Conditions
Anxiety Disorders Generalized, Depression
Interventions
Online Mothers and Babies Course (eMB)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Mother's Recorded Voice for Preterm Infants

NCT04559620
View directory record Official record
Conditions
Maternal Depressive Disorder Complicating Childbirth, Preterm Birth, Maternal Anxiety Disorder Complicating Childbirth
Interventions
Maternal voice
Other
Lead sponsor
AdventHealth
Other
Eligibility
Up to 3 Weeks
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mentors Offering Maternal Support (M-O-M-S™): A Prenatal Program for Decreasing Maternal Anxiety and Depression

NCT03393637
View directory record Official record
Conditions
Anxiety Fear, Prenatal Depression, Infant, Low Birth Weight, Preterm Birth, Maternal
Interventions
Mentors Offering Maternal Support (M-O-M-S)
Behavioral
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older · Female only
Enrollment
1,717 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
3
States / cities
San Diego, California • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Sep 30, 2026, 4:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes

NCT04993742
View directory record Official record
Conditions
Placental Dysfunction, Prenatal Stress
Interventions
MOMS Intervention
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal Sleep and Mental Health

NCT06544941
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior, Maternal Behavior, Inflammation, Military Family
Interventions
Smart Bassinet, HALO
Device
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meditation for NICU Moms

NCT03574766
View directory record Official record
Conditions
Breast Feeding, Premature Birth, Stress, Depression, Postpartum, Anxiety, Self Efficacy, Behavior, Maternal, Insufficient Lactation
Interventions
Meditation
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond Heights, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Sep 30, 2026, 4:56 PM EDT
Completed No phase listed Observational

Assessing the Impact of Mount Sinai Parenting Center's Newborn Class

NCT04121390
View directory record Official record
Conditions
Parenting Intervention
Interventions
Newborn Parenting Class
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Sep 30, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

NCT07792837
View directory record Official record
Conditions
Excessive Gestational Weight Gain, Pregnancy, INTUITIVE EATING, Perceived Stress, Prenatal Depression, Anxiety, Diet Quality, Physical Activity, Body Awareness
Interventions
Intuitive Eating Intervention
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

NCT04154423
View directory record Official record
Conditions
Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety, Depression, Postpartum, Satisfaction, Patient, Health Problems in Pregnancy
Interventions
Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Female only
Enrollment
678 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Fresno, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional

A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital

NCT05225025
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety
Interventions
ROSE, Standard of Care
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Sep 30, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery

NCT06949813
View directory record Official record
Conditions
Anxiety in Pregnancy, Mood Disorder Due to Specified Medical Condition
Interventions
BE-OR: Brief Intervention to the Operating Room, Interaction: Facetime with Clinical Provider
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

Restrained vs Gripping String Techniques in Patients Undergoing Cesarean Delivery

NCT07772219
View directory record Official record
Conditions
Maternal Anxiety, Cesarean Delivery
Interventions
Standard Forearm Restraint, Wrist-Level Gripping Restraint
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Recruiting Not applicable Interventional

The Mom and Infant Outcomes (MOMI) Study

NCT06277661
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
Interventions
MOMI PODS, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 30, 2026, 4:56 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Owlet Band Observational Study: Observe the Use of a New Pregnancy Tracker for Expecting Mothers

NCT04419051
View directory record Official record
Conditions
Pregnancy, Anxiety, Stress
Interventions
Owlet Band
Other
Lead sponsor
Owlet Baby Care, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
8,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Oct 1, 2020 · Synced Sep 30, 2026, 4:56 PM EDT
Completed Not applicable Interventional Results available

Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT)

NCT04153864
View directory record Official record
Conditions
Perinatal Depression
Interventions
Brief Behavioral Activation Treatment
Behavioral
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older · Female only
Enrollment
1,230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Evanston, Illinois • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 30, 2026, 4:56 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

New Mothers Alpha-Stim

NCT04770181
View directory record Official record
Conditions
Anxiety, Depression, Insomnia, Sleep Quality
Interventions
Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator)
Device
Lead sponsor
Christina Murphey, RN, PhD
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Sep 30, 2026, 4:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal Mental Health & SUD Screening and Treatment

NCT05764213
View directory record Official record
Conditions
Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
Interventions
Listening to Women & Pregnant and Postpartum People
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10,470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 30, 2026, 4:56 PM EDT