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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:36 AM EDT

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Showing 25–48 of 90 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Maxilla Clear all
Completed Phase 3 Interventional Results available

Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients

NCT01844830
View directory record Official record
Conditions
Anesthesia
Interventions
Tetracaine HCl 3% and Oxymetazoline HCl 0.05%, Placebo
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
3 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
Loma Linda, California • Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Phase 4 Interventional

Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox

NCT00668304
View directory record Official record
Conditions
Maxillary Sinusitis
Interventions
Avelox (Moxifloxacin, BAY12-8039)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
29
States / cities
Birmingham, Alabama • Hoover, Alabama • Jonesboro, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional

Hyrax Vs. Invisalign Palatal Expander Clinical Study

NCT06662279
View directory record Official record
Conditions
Malocclusions, Narrow Maxilla, Narrow Maxillary Arch, Crowding
Interventions
Removable Rapid Palatal Expander, Banded Palatal Expander
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
6 Years to 11 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Laguna Hills, California • Warner Robins, Georgia • Naperville, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 22, 2026, 4:36 AM EDT
Active, not recruiting Not applicable Interventional

Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients

NCT05264545
View directory record Official record
Conditions
Partially Edentulous Maxilla or Mandible
Interventions
PrimeTaper EV
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
25 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
8
States / cities
Aurora, Colorado • Broomfield, Colorado • Oakbrook Terrace, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects

NCT01701505
View directory record Official record
Conditions
Anesthesia
Interventions
400uL of Kovacaine Mist, 200uL of Kovacaine Mist, 120uL of Kovacaine Mist
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
3 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 22, 2026, 4:36 AM EDT
Completed No phase listed Interventional Results available

Immediate Placement and Stabilization of Dental Implants With Tetranite Stabilization Material in Mandibular and Maxillary Tooth Extraction Sites That Fail to Provide Adequate Primary Stability

NCT04121364
View directory record Official record
Conditions
Adhesive Dental
Interventions
Tetranite
Device
Lead sponsor
RevBio
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis

NCT01522131
View directory record Official record
Conditions
Furcation Defects, Periodontitis, Alveolar Bone Loss Beyond Furcation
Interventions
bioresorbable membrane alonewill be used for regeneration of the periodontium(control)
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading

NCT00748241
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Astra Tech Fixture ST
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2012 · Synced Oct 22, 2026, 4:36 AM EDT
Terminated Phase 3 Interventional Results available

Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth

NCT01660893
View directory record Official record
Conditions
Anesthesia
Interventions
Tetracaine HCl 3% and oxymetazoline HCl 0.05%, Tetracaine HCl 3%, Placebo
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
Baltimore, Maryland • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 22, 2026, 4:36 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive

NCT04473521
View directory record Official record
Conditions
Denture Retention
Interventions
Investigational denture adhesive cream, Super Poligrip Free
Device
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 22, 2026, 4:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Gingival Crevicular Fluid Characterization During Orthodontic Treatment

NCT04226469
View directory record Official record
Conditions
Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
Interventions
Tooth movement
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
11 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Conventional, Overdenture and Palateless Overdenture Oral Health Impact Comparison Study

NCT02731703
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
Overdenture treatment
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Oct 22, 2026, 4:36 AM EDT
Active, not recruiting No phase listed Observational

Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up

NCT07245810
View directory record Official record
Conditions
Mandibular Fractures, Facial Fracture, Maxilla Fracture, Orthognathic Surgical Procedures
Interventions
Orthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery
Device
Lead sponsor
Stryker Craniomaxillofacial
Industry
Eligibility
Not listed
Enrollment
726 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control

NCT05208892
View directory record Official record
Conditions
Postoperative Pain, Opioid Use
Interventions
SZMN block, SZMN block with Dexmedetomidine
Procedure
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior Jaw

NCT00545818
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™ length 6 mm, OsseoSpeed™ length 11 mm
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years to 70 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
2
States / cities
Los Angeles, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper Jaw

NCT00820235
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™, NobelSpeedy™ Replace®, NanoTite™ Certain® PREVAIL®
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
3
States / cities
Iowa City, Iowa • Chapel Hill, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Oct 22, 2026, 4:36 AM EDT
Completed No phase listed Observational

Focused Registry to Collect Clinical Data on the MatrixWAVE System

NCT03405389
View directory record Official record
Conditions
Mandibular Fractures
Interventions
MatrixWAVE MMF System
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Not yet recruiting Not applicable Interventional

Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment

NCT07727980
View directory record Official record
Conditions
Tooth Loss, Dental Implant, Clinical Trials, Randomized Controlled Trial, Immediate Dental Implant Placement, Molar Extraction Socket, Maxilla, MANDIBLE
Interventions
scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
20 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Bone Grafts on Facial Gingival Profile in Maxillary Anterior Single Tooth Replacement

NCT01547273
View directory record Official record
Conditions
Facial Gingival Profile
Interventions
bone graft inside socket only, bone graft inside and outside socket, no bone graft
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

Bone Level Tapered Multi-Center Study

NCT02569671
View directory record Official record
Conditions
Tooth Loss
Interventions
Straumann Bone Level Tapered Implant - Immediate Placement, Straumann Bone Level Tapered Implant - Delayed Placement
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
3
States / cities
Los Angeles, California • Gainesville, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

Study on ASTRA TECH Implant System, OsseoSpeed™ Implants in Patients Missing All Teeth in the Upper Jaw, Restored With Provisional Teeth Within 24 Hours

NCT00711022
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
ASTRA TECH Implant System, OsseoSpeed™, all dimensions.
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 16, 2014 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Control Trial Testing Connective Tissue Grafts vs. Allograft on Dental Implants

NCT01934530
View directory record Official record
Conditions
Dental Implant Soft Tissue Defects in the Anterior Maxilla
Interventions
Soft Tissue Grafting
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Open-Label Study of Efficacy and Recommended Dose of Kovacaine Mist for Anesthetizing Maxillary Teeth

NCT01479517
View directory record Official record
Conditions
Anesthesia
Interventions
Kovacaine Mist 0.1 mL x 4 sprays, Kovacaine Mist 0.2 mL x 2 sprays, Kovacaine Mist 0.2 mL x 1 spray
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 22, 2026, 4:36 AM EDT
Active, not recruiting Phase 2 Interventional

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

NCT04870762
View directory record Official record
Conditions
Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm, Maxillary Sinus Carcinoma, Nasal Cavity Carcinoma, Oral Cavity Carcinoma, Tongue Carcinoma, Tonsillar Carcinoma
Interventions
Best Practice, Medical Device Usage and Evaluation
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Phoenix, Arizona • Jacksonville, Florida • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 22, 2026, 4:36 AM EDT