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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:58 PM EDT

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Showing 1–24 of 105 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Median Neuropathy Clear all
Terminated Not applicable Interventional

Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release

NCT05325567
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Mini open incision CTR
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 20, 2026, 6:58 PM EDT
Not listed No phase listed Observational

Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study

NCT01897272
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Splinting
Behavioral
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 20, 2026, 6:58 PM EDT
Enrolling by invitation Not applicable Interventional

Assessment of Carpal Tunnel Syndrome by Shearwave Elastography

NCT04804293
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
FDA approved ultrasound system with shear wave elastography capability
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Outcomes of USCTR vs. mOCTR

NCT04504019
View directory record Official record
Conditions
Carpal Tunnel
Interventions
USCTR, mOCTR
Device · Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Phase 2 Interventional

Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome

NCT00991068
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Synera (lidocaine 70 mg and tetracaine 70 mg) topical patch
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Mechanisms of Neural Mobilization in the Treatment of Chronic Pain

NCT00929123
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
neural mobilization, sham neural mobilization, healthy controls
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional Results available

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

NCT05405218
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS, Carpal Tunnel
Interventions
CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Sonora, California • Fort Walton Beach, Florida • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Dorsal Kinesio Tape Application for Carpal Tunnel Syndrome in Esports Gamers: A Randomized Clinical Trial

NCT06993090
View directory record Official record
Conditions
Carpal Tunnel, Carpal Tunnel Syndrome (CTS)
Interventions
Kinesio Tape
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
3
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Phase 2 Interventional

Sham Device, Pill Placebo or Treatment For Arm Pain

NCT00029497
View directory record Official record
Conditions
Cumulative Trauma Disorders, Repetitive Strain Injury, Carpal Tunnel Syndrome, Pain
Interventions
Acupuncture, Amitriptyline
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional Results available

Testing of a Tool to Elicit Patient Preferences for CTS

NCT03532373
View directory record Official record
Conditions
Carpal Tunnel, Carpal Tunnel Syndrome, Carpal Tunnel Syndrome Left, Carpal Tunnel Syndrome Right, Carpal Tunnel Syndrome Bilateral
Interventions
Preference Elicitation tool
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Phase 1 Interventional

The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

NCT03729375
View directory record Official record
Conditions
Pain, Postoperative, Carpal Tunnel Syndrome
Interventions
10cc injection of bupivacaine, 20cc injection of bupivacaine
Drug
Lead sponsor
University of South Florida
Other
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 20, 2026, 6:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Analysis of Human Carpal Tunnel System

NCT02747836
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Ultrasound of the wrist
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 6:58 PM EDT
Terminated No phase listed Observational

Corticosteroid Injection as a Predictor of Outcome in Carpal Tunnel Release

NCT00655915
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Corticosteroid Injection- 1ml of Betamethasone and 1 ml of 1% Lidocaine
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 9, 2011 · Synced Oct 20, 2026, 6:58 PM EDT
Recruiting Not applicable Interventional

Comparing Efficacy of Osteopathic Manipulation vs. Wrist Immobilization for Carpal Tunnel Syndrome

NCT07432750
View directory record Official record
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
Osteopathic Manipulative Treatment, Wrist Immobilizer
Procedure · Device
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 20, 2026, 6:58 PM EDT
Terminated Not applicable Interventional

Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome

NCT01450735
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
MANOS CTR™
Device
Lead sponsor
Thayer Intellectual Property, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Hayward, California • San Francisco, California • Willits, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional

Early Motion Following Carpal Tunnel Release

NCT00845325
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Group One, Control Group Two
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 29, 2016 · Synced Oct 20, 2026, 6:58 PM EDT
Terminated Not applicable Interventional

The Effect of Surgical Incision Size on Carpal Tunnel Surgery

NCT00435071
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Carpal tunnel release surgery
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 18, 2011 · Synced Oct 20, 2026, 6:58 PM EDT
Not listed Not applicable Interventional

The Nutritional Benefits of Metanx in Patients With Diabetic Peripheral Neuropathy (MEDIAN)

NCT01990092
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy, B Vitamin Deficiency
Interventions
Metanx, Placebo
Other
Lead sponsor
Pamlab, Inc.
Industry
Eligibility
25 Years to 80 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
25
States / cities
Mobile, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 21 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2016 · Synced Oct 20, 2026, 6:58 PM EDT
Completed No phase listed Observational

DUCATS Trial: Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel Syndrome

NCT02219555
View directory record Official record
Conditions
Carpal Tunnel
Interventions
Steroid Injection, Carpel Tunnel surgery
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 80 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 20, 2026, 6:58 PM EDT
Completed No phase listed Observational

Carpal Tunnel/Amyloidosis Blood Sample Study

NCT02587728
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Amyloidosis
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Phase 4 Interventional

Narcotic vs. Non-narcotic Pain Study Protocol

NCT01974609
View directory record Official record
Conditions
Carpal Tunnel
Interventions
Narcotic, non-narcotic
Drug
Lead sponsor
Horizon Health Network
Other
Eligibility
18 Years to 90 Years
Enrollment
347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
3
States / cities
Philadelphia, Pennsylvania • Sioux Falls, South Dakota • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 20, 2026, 6:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain

NCT04060875
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction, Complex Regional Pain Syndromes, Phantom Limb Pain, Rheumatoid Arthritis, Carpal Tunnel Syndrome, Repetitive Strain Injury
Interventions
Karuna Labs Virtual Reality Software
Device
Lead sponsor
Karuna Labs Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 20, 2026, 6:58 PM EDT
Completed Not applicable Interventional

Carpal Tunnel Syndrome: Diagnosis and Treatment Trial

NCT00032227
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Oct 20, 2026, 6:58 PM EDT