Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 13, 2026, 6:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Substance-Related Disorders
Interventions: Randomized Drug Testing Trial; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Drug Use, Substance Abuse, Mental Illness
Interventions: Integrated Harm Reduction Intervention (IHRI); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 3
States / cities: New Haven, Connecticut • New York, New York • Orangeburg, New York

Conditions: Depression, Drug Abuse, Sexually Transmitted Diseases
Interventions: Cognitive Behavioral Therapy Development for Methamphetamine Abuse; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years · Male only
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Methamphetamine Dependence, Methamphetamine Abuse
Interventions: Methamphetamine, Placebo; Drug
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 55 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Neural Systems, Drug Abuse, Cocaine Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 50 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse, Substance Abuse, Opioid Use, Unspecified, Opioid Dependence, Drug Overdose
Interventions: TTIP-PRO; Behavioral
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Drug Abuse
Interventions: Brief advice, Brief Intervention plus Booster, Brief Intervention; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 417 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Substance Use, Sexual Risk Behaviors
Interventions: Risk Reduction Therapy for Adolescents, Usual services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Web app; Behavioral
Lead sponsor: Behavior Therapy Associates, LLP; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Levetiracetam (Keppra), Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 50 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Substance-Related Disorders
Interventions: On-site HIV rapid test and brief, prevention counseling, On- site HIV rapid test & information, Referral for off-site HIV testing; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 1,281 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 12
States / cities: Tucson, Arizona • Danbury, Connecticut • Plainville, Connecticut + 8 more

Conditions: HIV
Interventions: PATH For Triples, Treatment as Usual; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: Desipramine, Placebo; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 111 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1995 – 2002
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid-use Disorder
Interventions: Mindfulness Oriented Recovery Enhancement Sessions; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Drug Dependence, Pregnancy
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: Female only
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Abuse Potential
Interventions: gabapentin 600 mg, gabapentin 1200 mg, gabapentin 1800 mg, diazepam 20 mg, placebo; Drug · Other
Lead sponsor: Viatris Specialty LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Alcohol-Related Disorders, Anxiety Disorders
Interventions: Venlafaxine, CBT, Progressive muscle relaxation therapy (PMR), Placebo medication; Drug · Behavioral · Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Drug Abuse
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drug Use
Interventions: VOICES Group, Girl Health Group; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 12 Years to 24 Years · Female only
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: ADHD, Attention Deficit Hyperactivity Disorder
Interventions: Methylphenidate, Atomoxetine; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 7 Years to 12 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Dependence
Interventions: buprenorphine/naloxone combination; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use, Unsafe Sexual Behavior
Interventions: Familias Unidas; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 17 Years
Enrollment: 242 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Substance-Related Disorders, Drug Addiction, Substance Abuse
Interventions: Home-Based Intervention, Educational Group; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 12 Years to 19 Years
Enrollment: 286 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cocaine Abuse, Cocaine-Related Disorders
Interventions: Pregabalin, placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: West Haven, Connecticut

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Mentored Clinical Career Award in Adolescent Substance Abuse

Harm Reduction Services

Behavioral Therapy Development for Methamphetamine Abuse

Buspirone as a Candidate Medication for Methamphetamine Abuse

PET Assays of Striatal Dopamine Marker in Cocaine Craving

Phone Interview to Prevent Recurring Opioid Overdoses

Multidisciplinary Approach to Reduce Injury and Substance Abuse

Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth

A Web App for Patients With Alcohol and Drug Use Problems in Primary Care

Effects of Levetiracetam (Keppra) on Alcohol Consumption

Rapid HIV Testing and Counseling in Drug Abuse Treatment

PATH For Triples Study: Medication and Lifestyle Adherence for HIV+ Patients

New Approaches to Cocaine Abuse Medications (A) - 6

Mindfulness Oriented Recovery Enhancement in Hospitalized People With Opioid Use Disorder

The Effect of Fetal Gender on Maternal Substance Abuse Treatment

Evaluating the Abuse Potential of NEURONTIN® When Taken Orally in Healthy Non-drug Dependent Participants With Sedative Drug Abuse Experience

Psychosocial and Medication Treatment for Anxiety in Alcoholism

The Effects of Expectation on Natural and Drug -Induced Rewards

Gender-Responsive Drug Use Treatment for Juvenile Justice Girls

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse

Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders

Home-Based Program to Help Parents of Drug Abusing Adolescents

The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3