Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 3:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Opioid Abuse, Prescription Opioid Abuse
Interventions: Clinical Decision Support Tool (Moderate Risk), Clinical Decision Support Tool (High Risk), Standard of Care; Behavioral · Other
Lead sponsor: University of Utah; Other
Eligibility: Not listed
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Cincinnati, Ohio • Salt Lake City, Utah

Conditions: Methamphetamine Dependence, Methamphetamine Abuse
Interventions: Methamphetamine, Placebo; Drug
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 55 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Alcohol Abuse
Interventions: Brief Negotiated Interview, General Health Information; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 65 Years and older
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Alcohol-Related Disorders, Anxiety Disorders
Interventions: Venlafaxine, CBT, Progressive muscle relaxation therapy (PMR), Placebo medication; Drug · Behavioral · Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Methamphetamine Dependence
Interventions: Text messages; Behavioral
Lead sponsor: New Leaf Treatment Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Lafayette, California

Conditions: Pain, Appetite Loss, Abuse, Drug
Interventions: Placebo, Low CBG, High CBG, Low THC, High THC; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain, Abuse, Drug
Interventions: Active Cannabis, Placebo Cannabis; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 55 Years
Enrollment: 161 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Methamphetamine Addiction
Interventions: Dextroamphetamine, Placebo; Drug
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Opioid Dependence
Interventions: Memantine, Placebo; Drug
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 25 Years
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: HIV, Intravenous Substance Abuse, Women's Health, Organization and Administration, Primary Prevention, Implementation Science
Interventions: Practice Facilitation; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Drug Abuse
Interventions: Ramelteon, triazolam, and placebo (56 possible combinations total); Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance-related Disorders, Alcohol-related Disorders
Interventions: Specialized Substance Abuse Supervision (SSAS); Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 17 Years and older
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Drug Abuse
Interventions: Screening/motivational drug intervention, Motivational placebo intervention; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: San Diego, California

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Levetiracetam (Keppra), Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 50 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
Interventions: Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER), Continuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER); Drug
Lead sponsor: Member Companies of the Opioid PMR Consortium; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 61
States / cities: Foley, Alabama • Mobile, Alabama • Montgomery, Alabama + 49 more

Conditions: Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose, Substance Abuse, Intravenous Drug Usage, Opiate Substitution Treatment, Sexually Transmitted Diseases
Interventions: Health kiosk; Behavioral
Lead sponsor: April M Young; Other
Eligibility: 18 Years and older
Enrollment: 752 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Opiate Dependence, HIV Infections
Interventions: Buprenorphine/Subutex, Naltrexone, Drug counseling; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cannabis-use Disorders
Interventions: Pregabalin, Placebo; Drug
Lead sponsor: Joshua A. Lile, Ph.D.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse, Diet Modification, Health Behavior, Health Knowledge, Attitudes, Practice, Relationship, Family, Relation, Parent-Child, Emotional Stress
Interventions: Weaving Healthy Families Program; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 5 Years to 120 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Smoking Cessation
Interventions: Stepped-Care, Control; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Walnut Creek, California

Conditions: Substance-Related Disorders
Interventions: Rivastigmine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Neonatal Abstinence Syndrome
Interventions: Stochastic Vibrotactile Stimulation (SVS); Device
Lead sponsor: Elisabeth B Salisbury; Other
Eligibility: 1 Hour to 18 Months
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Recreational Drug Use
Interventions: PF614, Oxycodone Hydrochloride 40 mg, Placebo; Drug
Lead sponsor: Ensysce Biosciences; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
Interventions: Screening; Other
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Search by objective public record fields.

Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool

Buspirone as a Candidate Medication for Methamphetamine Abuse

Study of an Emergency Department-based Intervention to Reduce Alcohol Misuse in Older Adults

Psychosocial and Medication Treatment for Anxiety in Alcoholism

A Cognitive Behavioral Therapy-Based Text Messaging Intervention for Methamphetamine Dependence

AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)

Cannabis Effects as a Function of Sex

A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence

Memantine-enhanced Buprenorphine Treatment for Opioid-dependent Young Adults

Implementing PrEP for Women Who Inject Drugs

Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse

Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Offenders

Screening, Brief Intervention, and Referral to Treatment for Drug Use

Effects of Levetiracetam (Keppra) on Alcohol Consumption

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

HIV Risk Reduction and Drug Abuse Treatment in Iran

Behavioral Effects of Pregabalin and Cannabis

The Weaving Healthy Families Program

Interventions for Smoking Among Persons in Recovery

Rivastigmine For Methamphetamine Dependent Individuals

Efficacy and Outcomes of a Non-Pharmacological Intervention for Neonatal Abstinence Syndrome

A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users (PF614-104)

Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform