Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Drug Abuse
Interventions: Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET), Enhanced Usual Care (EUC); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 60 Years
Enrollment: 878 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Substance Use Disorders, Drug Abuse, Drug Addiction, Substance Abuse, Drug Use Disorders, Drug Dependence, Substance Addiction
Interventions: Treatment as Usual (TAU), TAU+CBT4CBT; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Drug Abuse
Interventions: Computerized Brief Intervention; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Edgewood, New Mexico

Conditions: Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients With Chronic Conditions
Interventions: MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing); Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
Interventions: AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central); Behavioral
Lead sponsor: Veterans Recovery Network Inc.; Other
Eligibility: 17 Years to 99 Years
Enrollment: 1,000,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2045
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Medication Abuse, Harm Reduction, Opioid Use Disorder, Supportive Care
Interventions: Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS); Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 89 Years
Enrollment: 200,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Substance Abuse Disorder
Interventions: PRSS (Peer Recovery Support Specialist); Other
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Substance-related Disorders
Interventions: Voucher-Based Reinforcement Therapy; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Schizophrenia, Mood Disorders, Substance Dependence
Interventions: Behavioral Treatment for Substance Abuse in SPMI (BTSAS), Supportive Treatment in Addiction Recovery (STAR), Critical Time Intervention (CTI); Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 55 Years
Enrollment: 293 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 4
States / cities: Baltimore, Maryland • Catonsville, Maryland

Conditions: Cocaine Dependence
Interventions: Ondansetron, Placebo; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Charlottesville, Virginia • Richmond, Virginia

Conditions: Drug Abuse Illicit
Interventions: Pilot Website Evaluation Component; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 212 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions: Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 652 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 4
States / cities: Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more

Conditions: Opioid-Related Disorders, HIV Infections, AIDS
Interventions: Buprenorphine, Integrated HIV care and office-based opioid dependence treatment; Drug · Behavioral
Lead sponsor: The New York Academy of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 1,350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 10
States / cities: Tucson, Arizona • Oakland, California • San Francisco, California + 7 more

Conditions: Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use, Substance Use, Methamphetamine Abuse, Methamphetamine-dependence
Interventions: App-Based Contingency Management, Sham Control; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Oconomowoc, Wisconsin • Wauwatosa, Wisconsin

Conditions: Opioid Abuse, Opioid Dependence, Opioid-Related Disorders, Opioid Use
Interventions: Lorcaserin, Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Abuse of Anabolic Steroids
Interventions: Testosterone; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Opioid Abuse, Overdose, Risk Behavior
Interventions: Naloxone Navigator 1.0; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Healthy Recreational Drug Users
Interventions: ACT-541468, Suvorexant, Zolpidem, Placebo; Drug
Lead sponsor: Idorsia Pharmaceuticals Ltd.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Drug Abuse, Cocaine Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 20 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Marijuana Abuse
Interventions: Cue Desensitization; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Alcohol Consumption, Drug Abuse
Interventions: Brief motivational substance use intervention; Behavioral
Lead sponsor: RAND; Other
Eligibility: 12 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Dependence, Chronic Hepatitis C
Interventions: Motivational Enhancement Therapy (MET), Health education; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Portland, Oregon

Conditions: ADHD, Attention Deficit Hyperactivity Disorder
Interventions: Methylphenidate, Atomoxetine; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 7 Years to 12 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Abuse, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
Interventions: Contingency Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Search by objective public record fields.

Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department

CBT4CBT for Women in Residential Treatment for Substance Use Disorders

Computerized Brief Intervention vs. Delayed Computerized Brief Intervention

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care

QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)

Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder

Machine Learning Technology in Predicting Relapse and Implementing Peer Recovery Intervention Before Drug Use Occurs

Voucher-Based Incentives in a Prevention Setting

Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients

New Medication Treatment for Stimulant Dependence

Drug User Internet and Mobile Tech Use

NC Young Women's CoOp

Buprenorphine and Integrated HIV Care Evaluation

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder

Intranasal Delivery of Testosterone and Its Effect on Doping Markers

Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders

Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users

Brain Glutamate Receptors and Cocaine Dependence

Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1

Brief Youth Substance Use Intervention for Primary Care

Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Contingency Management of Alcohol Abuse in the Severely Mentally ILL