Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 5:55 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Marijuana Abuse
Interventions: citicoline, placebo; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 45 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Drug Abuse/Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use, Relapse
Interventions: Dual Processing, Relapse Prevention; Behavioral
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Falls Church, Virginia

Conditions: Substance Abuse
Interventions: Standard Treatment As Usual (TAU), Individual clinician-provided CBT, CBT4CBT; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Methamphetamine Dependence, Methamphetamine Withdrawal
Interventions: Not listed
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions: Computer Screening, Brief Intervention, Referral toTreatment; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cocaine Abuse
Interventions: Treatment as usual (TAU), CBT for CBT; Other · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Abuse, Alcohol Dependence, Substance Abuse, Substance Dependence
Interventions: Motivational Enhancement Therapy, Education; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions: Active inhaled cannabis, Placebo, Active Oral Ethanol; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Opioid-related Disorders
Interventions: Heroin, Naloxone, Low Bup Dose, High Bup Dose, Low Bup/Nal Dose, High Bup/Nal Dose, Placebo (PCB); Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 45 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Abuse, HIV
Interventions: Tool to provide re-entry support and improve linkage to healthcare and social services; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use, Opioid Use Disorder, Drug Overdose, Overdose Prevention, Co-occurring Mental Health Conditions
Interventions: Practice Companion; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 14 Years to 24 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heroin Dependence, Opioid-Related Disorders, Cocaine Abuse or Dependence
Interventions: Not listed
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Brief Prevention Program Using Positive Image; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Cannabis Use, Drug Abuse
Interventions: Cannabis Cigarette; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions: Integrated Care for Smoking Cessation in PTSD patients, Standard of Care; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 943 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 11
States / cities: Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more

Conditions: Pain, Abuse, Drug
Interventions: Oxycodone, Cannabis (THC:CBD = ~ 1:0), Cannabis (THC:CBD = ~ 0:1), Cannabis (THC:CBD = ~ 1:1), Placebo; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 53 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain, Abuse, Drug, Intoxication; Cannabinoids
Interventions: Cannabis, Dronabinol, Smoked Placebo, Oral Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cocaine-Related Disorders, Opioid-Related Disorders, Heroin Dependence, Substance Abuse, Intravenous
Interventions: Abstinence & Work, Work Only; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions: Project CHOICE; Behavioral
Lead sponsor: RAND; Other
Eligibility: 11 Years to 15 Years
Enrollment: 6,455 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Antisocial Behavior
Interventions: Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 16 Years to 26 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 4
States / cities: Hamden, Connecticut • Hartford, Connecticut • New Haven, Connecticut + 1 more

Conditions: Drug Abuse
Interventions: brief intervention (cognitive-behavioral therapy); Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 13 Years to 19 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Alcohol and Drug Abuse
Interventions: Motivational interviewing case management, Resource referrals; Behavioral
Lead sponsor: Public Health Institute, California; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Emeryville, California

Conditions: Marijuana Abuse
Interventions: Yohimbine; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Detroit, Michigan

Search by objective public record fields.

Effects of Citicoline on Brain Function and Behavior in Marijuana-Dependent Individuals

Understanding Drug Abuse Treatment Outcomes

fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults

Computer Based Training in Cognitive Behavioral Therapy Web-based

Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study

cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use

Computer-Based Training in Cognitive Behavior Therapy

Efficacy Trial of Warrior Check-Up

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II

Abuse Liability of Suboxone Versus Subutex

Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System

Clinician Practice Companion to Address Youth Substance Use

Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals

Brief Integrative Alcohol Interventions for Adolescents

Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

Age-dependent Effects of Smoked and Oral Delta-9-THC

The Therapeutic Workplace Initiation Study

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

Brief Intervention for Drug Abusing Adolescents

Reducing Offenders' HIV Risk: MI Enhanced Case Management With Drug-Free Housing

Effects of Stress and Drug-cue Exposure (SCM)