Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 11, 2026, 2:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Opioid-Related Disorders
Interventions: Video-based DOT Application; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Boston, Massachusetts • Seattle, Washington

Conditions: Substance Abuse Detection
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 1 Year to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Davis, California

Conditions: Opioid-use Disorder
Interventions: BupreCare, Buprenorphine/naloxone, MEMS; Device · Drug · Other
Lead sponsor: MedicaSafe, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: San Diego, California • Baltimore, Maryland

Conditions: Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
Interventions: LST High School Hybrid; Behavioral
Lead sponsor: National Health Promotion Associates, Inc.; Industry
Eligibility: 14 Years to 18 Years
Enrollment: 1,804 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Adolescent Substance Use
Interventions: Teen Intervene, Everyday Parenting; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 12 Years to 17 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Alcohol Dependence (Primary Condition), Alcohol Abuse
Interventions: Memantine; Drug
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior, Benzodiazepine Abuse, Benzodiazepine Dependent
Interventions: Automated Reports on prescription patterns for their patients; Other
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 427 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Intimate Partner Violence
Interventions: Multi-media WINGS, Caseworker Delivered WINGS; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 209 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 3
States / cities: Brooklyn, New York • New York, New York

Conditions: Stress, Drug Abuse
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drug Abuse, HIV Risk Behavior
Interventions: Computerized brief intervention, Counselor delivered brief intervention; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco, School Failure
Interventions: whole day first grade program; Behavioral
Lead sponsor: American Institutes for Research; Other
Eligibility: Not listed
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Abuse, Cocaine Abuse, Marijuana Abuse
Interventions: MI-CBT, Brief Advice; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 16 Years to 45 Years · Female only
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 2
States / cities: Bridgeport, Connecticut • New Haven, Connecticut

Conditions: Cocaine Dependence, Cocaine Abuse, Cocaine Addiction, Drug Abuse, Substance Abuse
Interventions: quetiapine fumarate, Matched Placebo, Cognitive-behavioral Therapy; Drug · Behavioral
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Medication Abuse
Interventions: Clinical Decision Support (CDS) alerts; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 89 Years
Enrollment: 3,635 participants
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Interventions: Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Recreational Drug Use
Interventions: PF614, Oxycodone, Placebo; Drug · Other
Lead sponsor: Ensysce Biosciences; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Substance-Related Disorders
Interventions: Brief computer-delivered intervention; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Opioid Abuse, Opioid Dependence, Opioid-Related Disorders, Opioid Use
Interventions: Lorcaserin, Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions: Active delta-9-THC, Placebo, Active Ethanol; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Substance-Related Disorders, Hepatitis
Interventions: Pegylated Interferon; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 15 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Smoking, Alcohol Abuse, Drug Abuse
Interventions: Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 758 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Healthy
Interventions: Placebo, Oxycodone 20mg, gabapentin 600 mg, Gabapentin 1200mg, Gabapentin 600 mg + Oxycodone 20 mg, Gabapentin 1200 mg + Oxycodone 20 mg; Drug
Lead sponsor: Viatris Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Heroin Dependence
Interventions: Virtual Reality Cue Exposure Therapy, Relapse Prevention Drug Education; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Years to 64 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: HIV Infection, Substance Abuse
Interventions: Trans-theoretical Process of Change Model-self, Trans-theoretical Process of Change Model - interviewer; Behavioral
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 39 Years
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Search by objective public record fields.

Trial of Adherence App for Buprenorphine Treatment (TAAB) Study

Optimizing Toxicological Screening in Drug Endangered Children

Improving Office Based Treatment of Opioid Use Disorder With Technology

A High School Program for Preventing Prescription Drug Misuse

Differential Sensitivity Markers in Youth Drug Abuse Prevention

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

An Opioid Prescribing Nudge

Women Initiating New Goals of Safety

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

Screening Brief Intervention Referral to Treatment (SBIRT) in New Mexico

The Whole Day First Grade Program

Therapeutic Substance Abuse Treatment in Pregnancy - 1

Quetiapine for the Reduction of Cocaine Use

A Health System Wide Evaluation of Clinical Decision Support Tools to Improve PDMP Utilization and Patient Outcomes

CRAFT Behavior Therapy: Treatment Entry Component

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users (PF614-103)

Interactive Motivational Media for Perinatal Drug Abuse - 3

Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users

Dynamic Assessment and Referral System - Evaluation

Abuse Potential of Gabapentin Taken Orally Concomitantly With Oxycodone Hydrochloride in Healthy, Non-Drug-Dependent, Recreational Opioid Users

University of Houston Drug Abuse Research Development Program II

A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV