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ClinicalTrials.gov public records Last synced Nov 11, 2026, 11:01 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Schizophrenia, Drug Abuse/Dependency
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2013
U.S. locations: 2
States / cities: Baltimore, Maryland • Rockville, Maryland

Conditions: Aggression, Substance-Related Disorders
Interventions: MI-CBT, MI-CBT+CC, E-TAU; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cannabis Use, Tobacco Use Disorder, Drug Use Disorder
Interventions: N-Acetyl cysteine, Placebo comparator, Cognitive behavioral therapy (CBT); Drug · Other · Behavioral
Lead sponsor: Ellen Herbst; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Marijuana Dependence
Interventions: Nicotine, Placebo Patch; Drug
Lead sponsor: Southern Illinois University Carbondale; Other
Eligibility: 18 Years to 50 Years
Enrollment: 127 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Carbondale, Illinois

Conditions: Sports Drug Abuse, Abuse of Steroids or Hormones
Interventions: Clomid; Drug
Lead sponsor: Stuart Willick; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Opioid Related Disorders, Opioid Dependence, Opioid Addiction
Interventions: Buprenorphine/naloxone, Clonidine, Tramadol ER; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Reduction in Heavy Drinking in Patients With HIV
Interventions: Naltrexone, Placebo + Medication Management/Medication Coaching; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use, Relapse
Interventions: Dual Processing, Relapse Prevention; Behavioral
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Falls Church, Virginia

Conditions: Drug Abuse
Interventions: screening, assessment, referral, Brief intervention, booster sessions; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 1,285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 7
States / cities: Miami, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 4 more

Conditions: Cocaine Addiction
Interventions: lidocaine following cue-induced craving, lidocaine following neutral stimulus, saline; Drug
Lead sponsor: Bryon Adinoff; Other
Eligibility: 25 Years to 60 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Drug Abuse, Nicotine Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 525 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2005
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions: Integrated Care for Smoking Cessation in PTSD patients, Standard of Care; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 943 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 11
States / cities: Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more

Conditions: Marijuana Abuse
Interventions: citicoline, placebo; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 45 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Drug Abuse
Interventions: Integrated Family and Cognitive-Behavioral Therapy, Education; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 13 Years to 21 Years
Enrollment: 296 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drug Abuse, Cocaine Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Endocarditis
Interventions: Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin, Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline; Drug
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Drug Abuse, Alcohol Abuse
Interventions: Community Therapeutic Workplace; Behavioral
Lead sponsor: University of Maryland, Baltimore County; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opiate Withdrawal Syndrome, Drug Abuse in Pregnancy
Interventions: Buprenorphine Injection, Buprenorphine Sublingual Product; Drug
Lead sponsor: T. John Winhusen, PhD; Other
Eligibility: Not listed
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 10
States / cities: Jacksonville, Florida • Boston, Massachusetts • Portland, Oregon + 6 more

Conditions: Youths At-risk for Drug Use/Abuse
Interventions: Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 11 Years to 15 Years
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Methamphetamine Dependence, Methamphetamine Abuse
Interventions: Methamphetamine, Placebo; Drug
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 55 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Opiate Addiction
Interventions: Buprenorphine/naloxone, Naltrexone; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 16 Years to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Opioid-Related Disorders, Drug Abuse
Interventions: Contingency management, Cognitive-Behavior Therapy Modules, Peer Contingency Management (CM) Guide, Drug testing, Wellness modules, Peer technical support; Behavioral
Lead sponsor: Western Michigan University; Other
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Kalamazoo, Michigan

Conditions: Driving Behavior, Driving Under the Influence
Interventions: Placebo (Lactose) Capsule, 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD); Drug
Lead sponsor: Timothy L. Brown; Other
Eligibility: 19 Years to 45 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
Interventions: Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 11 Years to 14 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Influence of Nicotine on Cognitive Function in Schizophrenic Patients With and Without Comorbid Drug Dependence

Preventing Violence Among Veterans in Substance Use Disorder Treatment

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

Nicotine Patch for Marijuana Withdrawal

Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting

Medications Development for Drug Abuse Disorders

Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention

fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults

Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments

Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving

Cognitive Task Development and Implementation for Functional MRI Studies

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

Effects of Citicoline on Brain Function and Behavior in Marijuana-Dependent Individuals

Youth Drug Abuse Family and Cognitive-Behavioral Therapy

Reward Processing in Cocaine Addiction

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)

The Therapeutic Workplace Intervention in Community Settings

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study

Neurological Influences on Drug Prevention Intervention

Buspirone as a Candidate Medication for Methamphetamine Abuse

Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents

OUD Smartphone Services

Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim

Home Based Treatment for Drug Use in Early Adolescents