Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 11, 2026, 11:36 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Opiate Dependence
Interventions: Buprenorphine/Subutex, Naltrexone, Drug counseling; Drug · Procedure
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Mental and Behavioral Disorders Due to Harmful Drug Use
Interventions: HealthCall and Motivational Interviewing, Motivational Interviewing (MI), HIV/AIDS health education; Behavioral
Lead sponsor: Research Foundation for Mental Hygiene, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: New York, New York

Conditions: Juvenile Justice Involvement, Drug Abuse
Interventions: Middle School Success Intervention (MSS); Behavioral
Lead sponsor: Oregon Social Learning Center; Other
Eligibility: 10 Years to 12 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2013
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Abuse of Anabolic Steroids
Interventions: Testosterone; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Alcoholism
Interventions: Topiramate; Drug
Lead sponsor: Bankole Johnson; Other
Eligibility: 21 Years to 45 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 2
States / cities: Charlottesville, Virginia • Richmond, Virginia

Conditions: High Blood Pressure, Substance Abuse
Interventions: Usual Care, Contingency Management; Other · Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Cocaine Dependence
Interventions: levodopa/carbidopa 400/100 BID; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Methamphetamine Dependence, Methamphetamine Withdrawal
Interventions: Not listed
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Substance Abuse
Interventions: Computer-based Motivational Interviewing, Time control; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 143 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Pain, Cannabis, Opioid Use
Interventions: Within-subject test of blinded study medications; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drugs of Abuse
Interventions: HOPE supervision, Parole-as-usual; Behavioral
Lead sponsor: Pepperdine University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Cocaine Abuse, Heroin Abuse
Interventions: Clonidine, Placebo; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Abuse, Unspecified, Opioid Dependence
Interventions: Oxycodone/Placebo, Oxycodone/Risperidone, Oxycodone/Ziprasidone; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 21 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cannabis Use, Drug Abuse
Interventions: Cannabis Cigarette; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Healthy
Interventions: Placebo, Oxycodone + Naltrexone, Oxycodone; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Substance Abuse, HIV
Interventions: Computer-facilitated HIV intervention, Attention Control; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 371 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: Desipramine, Placebo; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 111 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1995 – 2002
U.S. locations: 1
States / cities: New York, New York

Conditions: ADHD, Attention Deficit Hyperactivity Disorder
Interventions: Methylphenidate, Atomoxetine; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 7 Years to 12 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Cocaine-Related Disorders, Heroin Dependence
Interventions: Buprenorphine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 26 Years to 41 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1989 – 1996
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia, Tourette Syndrome
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1998 – 2003
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Drug Abuse, Drug Dependence
Interventions: Prometa, Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Marijuana Dependence
Interventions: Standard CBT, CBT+CM/adherence, CM/abstinence, CM/abstinence+CBT; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Substance Use, Substance Abuse, Substance-Related Disorders
Interventions: Processing of clinical notes in the EHR data collected during routine care; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 89 Years
Enrollment: 64,996 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Marijuana Abuse
Interventions: Cue Desensitization; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Detroit, Michigan

Search by objective public record fields.

HIV Risk Reduction and Drug Abuse Treatment in Malaysia

HealthCall:Brief Intervention to Reduce Non-injecting Drug Use in HIV Primary Care Clinics

Prevention Program for Problem Behaviors in Girls in Foster Care

Intranasal Delivery of Testosterone and Its Effect on Doping Markers

New Medications to Treat Alcohol Dependence

Improving Antihypertensive Medication Adherence

Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse

Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study

Computer-based Brief Intervention for Perinatal Substance Abuse

Enhancing Medication-based Analgesia in Humans- STUDY 2

An Evaluation of California's Experiment With HOPE

Effect of Clonidine on Responses to Imagery Scripts

Reducing the Abuse of Opioids in Drug Users

Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis

A Study to Characterize the Abuse Liability of Intravenous Oxycodone Alone or in Combination With Intravenous Naltrexone in Healthy, Non-Dependent, Recreational Opioid Users

Reducing High Risk Behavior in Treatment Court

New Approaches to Cocaine Abuse Medications (A) - 6

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Treatment Efficacy for Drug Abuse and AIDS Prevention - 2

I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers

Prometa Pharmacotherapy for Methamphetamine Dependence

Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management

Data-driven Identification for Substance Misuse

Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1