Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 12, 2026, 4:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Healthy Non-dependent, Recreational Sedative Users
Interventions: Alprazolam (Xanax), Placebo, Gabapentin (Neurontin® (Registered Trademark)); Drug
Lead sponsor: Viatris Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Brief Intervention; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 14 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Healthy Volunteer
Interventions: Placebo, RO4917838, diazepam; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 177 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence, Cannabis Abuse
Interventions: Placebo Aprepitant, Active Aprepitant; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 45 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Charlottesville, Virginia

Conditions: Drug Use
Interventions: VOICES Group, Girl Health Group; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 12 Years to 24 Years · Female only
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Abuse Potential
Interventions: gabapentin 600 mg, gabapentin 1200 mg, gabapentin 1800 mg, diazepam 20 mg, placebo; Drug · Other
Lead sponsor: Viatris Specialty LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Antisocial Behavior
Interventions: Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 16 Years to 26 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 4
States / cities: Hamden, Connecticut • Hartford, Connecticut • New Haven, Connecticut + 1 more

Conditions: Opiate Abuse, Opiate Overdose, Opioid-use Disorder
Interventions: Peer Addiction Counseling; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Stigma, Activity Space, Social Networks, HIV Status, Drug Abuse/Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 1,651 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Buprenorphine, HIV, Drug Abuse, Drug Addiction, Drug Dependence, Drug Use Disorders, Drug Use Disorder, Substance Abuse, Opiate Addiction, Substance-related Disorders
Interventions: Services will be provided at one site, Services remain dispersed; i.e., not centralized to one-location or provider.; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Chronic Pain
Interventions: buprenorphine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Adolescent, Substance Use
Interventions: Modified traditional martial arts training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 13 Years to 17 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Opioid Use, Prescription Drug Abuse and Dependency, Surgery, Postoperative Pain
Interventions: No opioids at discharge; Behavioral
Lead sponsor: Albany Medical College; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Albany, New York

Conditions: Cannabis-use Disorders
Interventions: Pregabalin, Placebo; Drug
Lead sponsor: Joshua A. Lile, Ph.D.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: HEPATITIS C, Virus, Human Immunodeficiency
Interventions: Directly Observed Therapy, Wirelessly Observed Therapy; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 70 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Other Drug Substance Abuse
Interventions: Iwin: Individual Well-Being Navigator; Behavioral
Lead sponsor: Pro-Change Behavior Systems; Other
Eligibility: 18 Years to 54 Years
Enrollment: 253 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 4
States / cities: Watertown, Massachusetts • Poughkeepsie, New York • South Kingstown, Rhode Island + 1 more

Conditions: Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions: Computer Screening, Brief Intervention, Referral toTreatment; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Drug Abuse
Interventions: Reinforcement Based Treatment; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 463 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drug Abuse
Interventions: WIDUS computer-delivered, indirect brief intervention, Nutrition time control/placebo intervention; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: Carbamazepine; Drug
Lead sponsor: University of Kansas; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1990
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Alcohol Abuse, Drug Abuse
Interventions: Multimedia 12-Step Toolkit, Treatment as Usual; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 3,483 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 11
States / cities: Camden, New Jersey • Brooklyn, New York • Eagleville, Pennsylvania + 2 more

Conditions: Substance Use, Unsafe Sexual Behavior
Interventions: Familias Unidas; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 17 Years
Enrollment: 242 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Poly Drug Exposed Pregnancies
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome, Drug Abuse in Pregnancy
Interventions: Buprenorphine Injection, Buprenorphine Sublingual Product; Drug
Lead sponsor: T. John Winhusen, PhD; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 12
States / cities: Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more

Search by objective public record fields.

Abuse Potential of Oral Gabapentin in Healthy, Non-Drug-Dependent Individuals With Recreational Sedative Drug Use Experience

Reducing Problematic Substance Use in Youth With Chronic Medical Conditions

A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users

Medications Development for the Treatment of Cannabis Related Disorders

Gender-Responsive Drug Use Treatment for Juvenile Justice Girls

Evaluating the Abuse Potential of NEURONTIN® When Taken Orally in Healthy Non-drug Dependent Participants With Sedative Drug Abuse Experience

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

FAVOR Opioid Recovery Coaching Evaluation

Health Outcomes by Neighborhood - Baltimore

Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)

Sublingual Buprenorphine for Chronic Pain

Martial Arts as Early Intervention for Teen Drug Abuse

No Opioids PrescrIptions On Discharge After Surgery

Behavioral Effects of Pregabalin and Cannabis

Antiviral Pharmacology and Adherence in Drug Users

Iwin: Individual Well-Being Navigator

cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use

Reinforcement-Based Treatment and Abstinence-Contingent Housing for Drug Abusers

Indirect Assessment and Intervention for Perinatal Drug Use

Pharmacotherapy and Intensive Treatment of Drug Abuse - 1

Multimedia Toolkits to Implement 12-Step Recovery Concepts in Group Counseling

Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders

Fetal Neurobehavior in Poly-drug Dependent Women

Medication Treatment for Opioid Use Disorder in Expectant Mothers