Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 12, 2026, 7:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Medication Adherence
Interventions: Automated Adherence Monitoring System; Other
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Opioid Use, Opioid Abuse
Interventions: Sociobehavioral Intervention; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 163 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome, Drug Abuse in Pregnancy
Interventions: Buprenorphine Injection, Buprenorphine Sublingual Product; Drug
Lead sponsor: T. John Winhusen, PhD; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 12
States / cities: Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more

Conditions: Relationship, Family (Foster), Substance Use Prevention
Interventions: Connecting; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 11 Years to 15 Years
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use, Substance Use, Methamphetamine Abuse, Methamphetamine-dependence
Interventions: App-Based Contingency Management, Sham Control; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Oconomowoc, Wisconsin • Wauwatosa, Wisconsin

Conditions: Alcohol Abuse
Interventions: cASBI+cMET, cASBI; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prescription Drug Abuse
Interventions: MyHealthyChoices, Health Risk Assessment; Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Morgantown, West Virginia

Conditions: Cannabis Use Disorder
Interventions: N-acetyl cysteine, Placebo oral capsule; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 14 Years to 21 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions: Active Dronabinol, Placebo, Active Ethanol; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Opiate Substitution Treatment
Interventions: Standard Medical Management (SMM); Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 239 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Prescription Drug Abuse (Not Dependent)
Interventions: Oxycodone Medication First, Placebo First; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Consumption, Drug Abuse
Interventions: Brief motivational substance use intervention; Behavioral
Lead sponsor: RAND; Other
Eligibility: 12 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Drug Overdose, Opioid-Related Disorders, Drug Addiction, Drug Abuse, Substance Abuse
Interventions: Peer Intervention, naloxone nasal spray kit, Personally-tailored opioid overdose prevention education (information packet); Behavioral · Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Substance Abuse
Interventions: Free2b, Attention-Placebo; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 15 Years to 17 Years
Enrollment: 1,216 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Abuse
Interventions: AGATE, SASED; Other
Lead sponsor: Talaria, Inc; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Drug Use, Drug Abuse, Posttraumatic Stress Disorder
Interventions: PPRS, PIRI; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 15 Years to 90 Years · Female only
Enrollment: 245 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Minneapolis, Minnesota

Conditions: Schizophrenia, Mood Disorders, Substance Dependence
Interventions: Behavioral Treatment for Substance Abuse in SPMI (BTSAS), Supportive Treatment in Addiction Recovery (STAR), Critical Time Intervention (CTI); Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 55 Years
Enrollment: 293 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 4
States / cities: Baltimore, Maryland • Catonsville, Maryland

Conditions: Substance Use Disorders
Interventions: Voucher Reinforcement, Standard Control; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Abuse Potential
Interventions: gabapentin 600 mg, gabapentin 1200 mg, gabapentin 600 mg and oxycodone HCl 20 mg, gabapentin 1200 mg and oxycodone HCl 20 mg, oxycodone HCl 20 mg, placebo; Drug
Lead sponsor: Viatris Specialty LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Marlton, New Jersey

Conditions: Alcoholism, Alcohol Abuse, Smoking, Alcohol Drinking
Interventions: Varenicline; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: New Haven, Connecticut • New York, New York

Conditions: Cocaine Addiction, Cocaine Dependence
Interventions: Vigabatrin, Matching Placebo; Drug
Lead sponsor: Catalyst Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 13
States / cities: Los Angeles, California • Torrance, California • Denver, Colorado + 10 more

Conditions: Prevention Harmful Effects
Interventions: computer-facilitated brief intervention; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 9 Years to 18 Years
Enrollment: 871 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 5
States / cities: Boston, Massachusetts • East Boston, Massachusetts • Lexington, Massachusetts

Conditions: HIV/AIDS, Substance Abuse
Interventions: Directly Administered Antiretroviral Therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Drug Abuse
Interventions: Brief advice, Brief Intervention plus Booster, Brief Intervention; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 417 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Austin, Texas

Search by objective public record fields.

Adherence Monitoring For Substance Abuse Clinical Trials

Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

A Trial of Connecting to Promote Foster Teen Well-Being

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

Pilot Test of Computerized MET to Reduce Adolescent Alcohol Use

Using m-Health Tools to Reduce the Misuse of Opioid Pain Relievers

N-Acetylcysteine for Youth Cannabis Use Disorder

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

Influence of Medication on Functional Connectivity

Brief Youth Substance Use Intervention for Primary Care

A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses

Preventing Drug Abuse Among Sexual Minority Youth

Adaptive Goal-Directed Adherence Tracking and Enhancement

Prevention of Post Sexual Assault Stress

Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients

Treatment for Psychological and Drug Abuse Problems

Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users

Varenicline Treatment of Alcohol Dependence in Smokers

Vigabatrin for the Treatment of Cocaine Dependency

Computerized Alcohol Screening for Children and Adolescents (cASCA) in Primary Care

Directly Observed Antiretroviral Therapy Among Active Drug Users

Multidisciplinary Approach to Reduce Injury and Substance Abuse