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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Medications for Alcohol Use Disorder Clear all
Completed Phase 1Phase 2 Interventional

Developing Violence Prevention Therapy for Substance Abusers

NCT00551863
View directory record Official record
Conditions
Substance Use Disorders, Violence
Interventions
IVPT
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 6, 2015 · Synced Sep 28, 2026, 4:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Infection Rates Between Two Surgical Sites

NCT01263262
View directory record Official record
Conditions
Corneal Toxicity, Ototoxicity, Surgical Site Infection
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2013 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Phase 2 Interventional Results available

Medication Development in Alcoholism: Suvorexant Versus Placebo

NCT04229095
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Suvorexant 20 mg, Placebo oral tablet
Drug
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 28, 2026, 4:52 AM EDT
Active, not recruiting Not applicable Interventional

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

NCT04955795
View directory record Official record
Conditions
Hiv, Alcohol Problem
Interventions
Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Recruiting Phase 2 Interventional

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

NCT07040592
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), HIV
Interventions
semaglutide
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Phase 1 Interventional Results available

ED Initiated Oral Naltrexone for AUD

NCT04817410
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Emergency Department Initiated Oral Naltrexone
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 28, 2026, 4:52 AM EDT
Terminated Phase 4 Interventional

CBT-I Augmentation of Medication for Drinking in AUD

NCT04581603
View directory record Official record
Conditions
Alcohol Use Disorder With Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Coatesville, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)

NCT01365247
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, Relapse Prevention Treatment, Active Monitoring Control Group
Behavioral
Lead sponsor
The City College of New York
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users

NCT04007666
View directory record Official record
Conditions
Substance Use Disorders, Drug Abuse, Alcohol Abuse, Posttraumatic Stress Disorder, PTSD, Recidivism, Depression
Interventions
Cognitive Processing Therapy, Control Group
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Osceola, Arkansas • West Memphis, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Not applicable Interventional

Brief New Treatment for Suicide Attempts

NCT03300596
View directory record Official record
Conditions
Suicide, Attempted, Drug Use, Alcohol; Use, Problem
Interventions
Brief intervention to prevent suicide attempt, Enhanced treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Sep 28, 2026, 4:52 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

90-Day Online Substance Use Program

NCT03069118
View directory record Official record
Conditions
Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
Interventions
Treatment - Workit Health Online Program, Control - Resource List
Behavioral
Lead sponsor
Workit Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 28, 2026, 4:52 AM EDT
Not yet recruiting Not applicable Interventional

Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

NCT07001371
View directory record Official record
Conditions
Cannabis Use Disorder, Stimulant Use Disorder, Opioid Use Disorder, Tobacco Use Disorder, Alcohol Use Disorder, Sedative, Hypnotic, or Anxiolytic Use Disorders
Interventions
Emotional Brain Training, Standard addiction counseling and medical therapy
Behavioral · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Terminated Phase 2 Interventional Results available

HLAB-002 of ANS-6637 for Alcohol Use Disorder

NCT03970109
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
ANS-6637, Placebo oral tablet
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
New Haven, Connecticut • Providence, Rhode Island • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 28, 2026, 4:52 AM EDT
Recruiting Phase 2 Interventional

Cannabidiol and Alcohol Use Disorder Phenotypes

NCT07279558
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Full-Spectrum Cannabidiol (CBD), Broad-Spectrum Cannabidiol (CBD), Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Withdrawn Phase 2 Interventional

Development of a Selective ALDH2 Inhibitor to Treat AUD

NCT04311294
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
ANS-6637 Low Dose, ANS-6637 High Dose, Matched Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Sep 28, 2026, 4:52 AM EDT
Active, not recruiting Not applicable Interventional

Addressing Barriers to Care for Substance Use Disorder Trial

NCT06729957
View directory record Official record
Conditions
Drug Use Disorders, Alcohol-Related Disorders, Substance Use Disorder (SUD)
Interventions
Care Navigation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)

NCT03575403
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol, Placebos, Duloxetine (60 MG), Methylphenidate, Duloxetine (30 MG)
Drug
Lead sponsor
Craig Rush
Other
Eligibility
21 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Not yet recruiting Not applicable Interventional

A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease

NCT07553377
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Associated Liver Disease, Medications for Alcohol Use Disorder, Behavioral Medicine, Medication Adherence
Interventions
AcamproSync
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dynamic Assessment and Referral System - Evaluation

NCT01153373
View directory record Official record
Conditions
Smoking, Alcohol Abuse, Drug Abuse
Interventions
Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
758 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Sep 28, 2026, 4:52 AM EDT
Recruiting Not applicable Interventional

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

NCT06923423
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD), Depression, Mental Health, Trauma, Trauma Exposure, Traumatic Stress Disorder, Traumatic Stress, Post Traumatic Stress Symptoms
Interventions
Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Little Rock, Arkansas • Osceola, Arkansas • Texarkana, Arkansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Building Recovery By Improving Goals, Habits, and Thoughts

NCT01191788
View directory record Official record
Conditions
Depression, Substance Use
Interventions
Group Cognitive Behavioral Therapy, Group CBT for Depression
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Gardena, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Youth Substance Use Intervention for Primary Care

NCT00292240
View directory record Official record
Conditions
Alcohol Consumption, Drug Abuse
Interventions
Brief motivational substance use intervention
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 28, 2026, 4:52 AM EDT
Completed Phase 4 Interventional Results available

Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users

NCT02445339
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorder
Interventions
XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 28, 2026, 4:52 AM EDT
Completed No phase listed Observational

Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement

NCT00593034
View directory record Official record
Conditions
Substance-related Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 7, 2011 · Synced Sep 28, 2026, 4:52 AM EDT