- Conditions
- Mild Cognitive Impairment, Subjective Memory Decline
- Interventions
- Tai Chi, Preventing Loss of Independence through Exercise (PLIE), Health and Wellness Education
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
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Showing 1–24
of 77
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Cognitive Function, Memory, Cognitive Decline
- Interventions
- Dietary Supplement: Brain Blossom, Placebo
- Dietary Supplement
- Lead sponsor
- Bio Nature Health
- Industry
- Eligibility
- 50 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Mild Cognitive Impairment
- Interventions
- Sham TBS, Closed-loop TBS, Open-loop TBS
- Device
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Age-Related Memory Disorders
- Interventions
- ispronicline (nicotinic acetylcholine receptor agonist)
- Drug
- Lead sponsor
- Targacept Inc.
- Industry
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 174 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005
- U.S. locations
- 15
- States / cities
- Mesa, Arizona • Peoria, Arizona • Denver, Colorado + 12 more
- Conditions
- Long-Term Memory Decline, Mild Cognitive Impairment
- Interventions
- LabyrinthVR, Placebo Games, Coherence, Tablet
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 62 Years to 85 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Age-Related Cognitive Decline, Age-Related Memory Disorders
- Interventions
- DHA (nutritional supplement) or placebo
- Dietary Supplement
- Lead sponsor
- dsm-firmenich Switzerland AG
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 485 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 14
- States / cities
- Mesa, Arizona • San Diego, California • Vista, California + 11 more
- Conditions
- Memory Loss, Postmenopause
- Interventions
- Isoflavones
- Drug
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- NIH
- Eligibility
- 62 Years and older · Female only
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2007
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
- Interventions
- Piano lessons, Music Lessons
- Behavioral
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Hot Flashes, Memory Loss
- Interventions
- PhytoSERM tablet, placebo
- Dietary Supplement
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 45 Years to 60 Years · Female only
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Alzheimer Disease, Memory Loss
- Interventions
- Transcranial alternating current stimulation (tACS)
- Device
- Lead sponsor
- Hebrew SeniorLife
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Kidney Diseases, Dementia, Dementia, Vascular, Stroke, Alzheimer Disease, Cognitive Decline, Cognitive Impairment, Cognitive Dysfunction, Kidney Diseases, Diabetes, Cerebral Atrophy, Small Vessel Ischemic Disease
- Interventions
- Not listed
- Lead sponsor
- Anne Murray
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2026
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota
- Conditions
- Cognitive Decline, Cognitive Function
- Interventions
- MindMD Supplement, Placebo
- Dietary Supplement · Other
- Lead sponsor
- Scale Media Inc
- Industry
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Santa Monica, California
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Cognitive Deterioration, Cognitive Deficits, Mild, Cognitive Impairment, Mild
- Interventions
- Brain Health Academy, Brain Health Together, Maintain Brain Health Together
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Mild Cognitive Impairment
- Interventions
- Grape Powder, Placebo Powder
- Dietary Supplement
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 65 Years to 85 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Alzheimer's Disease
- Interventions
- Resonator, Placebo
- Device
- Lead sponsor
- pico-tesla Magnetic Therapies, LLC
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 2
- States / cities
- Denver, Colorado • Clearwater, Florida
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Interventions
- pain delivery
- Procedure
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Post-Operative Cognitive Decline in Older Adults
- Interventions
- Magnetic Resonance Imaging, Cognitive assessment testing
- Other · Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
- Interventions
- Active Brains 1, Active Brains 2
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 267 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Down Syndrome, Mild Cognitive Impairment
- Interventions
- Low Dose Nicotine (7mg), Moderate Dose Nicotine (14mg)
- Drug
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Memory Loss
- Interventions
- Cocoa Flavanol
- Dietary Supplement
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 211 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Interventions
- Aerobic exercise, Stretching/balance/range of motion exercise
- Behavioral
- Lead sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
- Other
- Eligibility
- 65 Years to 89 Years
- Enrollment
- 296 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 14
- States / cities
- Irvine, California • Palo Alto, California • New Haven, Connecticut + 10 more
- Conditions
- Parkinson Disease, Mild Cognitive Impairment
- Interventions
- Strategy Training (Time- and Event- Based)
- Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Memory Disorders, Alzheimer Disease, Dementia, Cognitive Impairment, Frontotemporal Dementia
- Interventions
- COGNISION™ System
- Device
- Lead sponsor
- Neuronetrix, Inc.
- Industry
- Eligibility
- 60 Years to 90 Years
- Enrollment
- 204 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2014
- U.S. locations
- 7
- States / cities
- West Palm Beach, Florida • Lexington, Kentucky • Louisville, Kentucky + 4 more
- Conditions
- Depression, Mild Cognitive Impairment
- Interventions
- Donepezil, Placebo, Citalopram, Venlafaxine
- Drug
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 55 Years to 95 Years
- Enrollment
- 86 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 2
- States / cities
- New York, New York • Durham, North Carolina