Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:52 AM EDT

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Showing 145–168 of 892 matching trials from the live ClinicalTrials.gov search.
Conditions
Healthy Volunteers
Interventions
Transcranial Magnetic Stimulation Sham, Transcranial Magnetic Stimulation
Drug · Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Aging
Interventions
Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions, Sham transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years to 85 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Dementia
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older · Female only
Enrollment
2,922 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Phase 2 Interventional Accepts healthy volunteers

SMART: Somatotrophics, Memory, and Aging Research Trial

NCT00257712
Conditions
Aging, Mild Cognitive Impairment
Interventions
TH9507 human growth hormone releasing hormone (GHRH)
Drug
Lead sponsor
University of Washington
Other
Eligibility
55 Years to 90 Years
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alzheimer Disease
Interventions
Spaced Retrieval Training
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Little Rock, Arkansas
Recruiting Not applicable Interventional Accepts healthy volunteers

mPATH for Low-income Older Adults

NCT05935241
Conditions
Sedentary Time, Insomnia, Cognitive Decline
Interventions
mPATH, Attention Control
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Down Syndrome Memantine Follow-up Study

NCT02304302
Conditions
Down Syndrome, Intellectual Disability
Interventions
Memantine, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
15 Years to 32 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Rectal Cancer
Interventions
CEA protein antigen plus BCG Vaccine Mix for percutaneous use
Biological
Lead sponsor
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair
Industry
Eligibility
24 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rockville, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Executive Function Training for Children and Adolescents

NCT07147894
Conditions
Cognitive Change
Interventions
Nongamified N-back training, Gamified N-back training, Multiple Domain Training, Coaching Session
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
12 Years to 17 Years
Enrollment
780 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional

Cognitive-motor Training for PD

NCT01917903
Conditions
Parkinson's Disease
Interventions
Gait-cognitive training, Identification of at risk variables
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Traumatic Brain Injury, Cognitive Impairment
Interventions
SME
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Conditions
Traumatic Brain Injury, Memory Deficits
Interventions
Donepezil, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
4
States / cities
Indianapolis, Indiana • Charlestown, Massachusetts • Elkins Park, Pennsylvania + 1 more
Conditions
Cognitive Performance, Memory, Mood, Anxiety
Interventions
Muscadine Wine Polyphenol, Placebo
Other
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Traumatic Brain Injury
Interventions
BrainHQ Cognitive Training Modules, BrainHQ People Skills Modules
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Terminated No phase listed Observational Accepts healthy volunteers

The Role of Mid-Life Adiposity in Functional Brain Connectivity

NCT01777789
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Dementia, Delirium
Interventions
Robotic Joy for All™ pet
Behavioral
Lead sponsor
Sarasota Memorial Health Care System
Other
Eligibility
65 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sarasota, Florida
Conditions
Posttraumatic Stress Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
45 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Epilepsy
Interventions
Baseline MEG Test, Receptive Language Task, Memory Task
Diagnostic Test · Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
8 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Alzheimer Disease (AD)
Interventions
Zagotenemab, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
60 Years to 85 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
49
States / cities
Phoenix, Arizona • Tucson, Arizona • Encino, California + 45 more
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Hyperbaric Oxygen Therapy on Children With Autism

NCT00406159
Conditions
Autism
Interventions
Hyperbaric Oxygen Therapy
Device
Lead sponsor
Thoughtful House
Other
Eligibility
2 Years to 10 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Austin, Texas
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Network-Level Mechanisms for Preclinical Alzheimer's Disease Development

NCT03461861
Conditions
APOE 4
Interventions
AGB101 220 mg, Placebo
Drug · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
55 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Healthy, Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 18 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas