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Conditions: Dysmenorrhea, Pain
Interventions: Naproxen; Drug
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Evanston, Illinois

Conditions: Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder, Dysthymic Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Contraception
Interventions: Levonorgestrel IUS (Mirena, BAY86-5028); Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 364 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 49
States / cities: Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 44 more

Conditions: Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain, Endometriosis
Interventions: Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy; Procedure
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Endometriosis
Interventions: NettleEndo, Sham NettleEndo Device; Device
Lead sponsor: Samphire Group, Inc.; Industry
Eligibility: 22 Years to 45 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Menstrual Pain, Premenstrual Syndrome
Interventions: Pamprin Botanicals, Pamprin Botanicals + Pamprin Menstrual Pain Relief; Other · Combination Product
Lead sponsor: Focus Consumer Healthcare; Industry
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Premenstrual Syndrome, Menstrual Symptoms
Interventions: Two Moons Seed Cycling Capsules; Dietary Supplement
Lead sponsor: Superlune Inc. d/b/a Two Moons Health; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Menorrhagia
Interventions: tranexamic acid; Drug
Lead sponsor: Ferring Pharmaceuticals; Industry
Eligibility: 12 Years to 16 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Cypress, California

Conditions: Dysmenorrhea, Dysmenorrhea Primary, Visceral Pain, Menstrual Pain
Interventions: Visceral Pain Stimulus; Diagnostic Test
Lead sponsor: Azusa Pacific University; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Azusa, California

Conditions: Menorrhagia, Heavy Menstrual Bleeding, Heavy Uterine Bleeding
Interventions: Minitouch System; Device
Lead sponsor: MicroCube, LLC; Industry
Eligibility: 30 Years to 50 Years · Female only
Enrollment: 219 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 5
States / cities: Newburgh, Indiana • Mason, Ohio • Austin, Texas

Conditions: Uterine Fibroids (UF)
Interventions: Not listed
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 50 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Arlington, Virginia

Conditions: Contraception, Menorrhagia
Interventions: ESS305 (Essure, BAY1454032), NovaSure; Device · Procedure
Lead sponsor: Bayer; Industry
Eligibility: 21 Years to 50 Years · Female only
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2021
U.S. locations: 17
States / cities: Aurora, Colorado • Ocala, Florida • Decatur, Illinois + 14 more

Conditions: Healthy, Premenstrual Dysphoric Disorder, Premenstrual Syndrome
Interventions: Mixhers HERTIME, Placebo; Dietary Supplement
Lead sponsor: Midwestern University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Glendale, Arizona

Conditions: Type 1 Diabetes Mellitus
Interventions: Continuous Glucose Monitor; Device
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Menstrual Cycle and Uterine Bleeding Disorders
Interventions: Estradiol, Lysteda; Drug
Lead sponsor: Kay I Waud MD PhD; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Norfolk, Virginia

Conditions: Depression, Major Depressive Disorder, Premenstrual Dysphoric Disorder, Depressive Episode
Interventions: XCSITE100 Stimulator Sham, XCSITE100 Stimulator tACS; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Amenorrhea, Hypoaldosteronism, Hypogonadism, Infertility, Premature Ovarian Failure
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 42 Years · Female only
Enrollment: 1,134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1991 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Heavy Menstrual Bleeding
Interventions: Tranexamic Acid; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 10 Years to 19 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 5
States / cities: Indianapolis, Indiana • Kansas City, Missouri • Akron, Ohio + 2 more

Conditions: Amenorrhea, Premature Ovarian Failure, Ovarian Function Insufficiency
Interventions: Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation; Drug · Behavioral · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Up to 40 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Inflammatory Bowel Diseases, Contraception, Menstrual Problem
Interventions: Proposed study design and randomization scenarios, Repeated measures of validated Inflammatory Bowel Disease Patient Reported Outcome Instruments, Inflammatory marker collection and assessment for correlation with PRO responses and menstrual timing; Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Uterine Fibroids, Heavy Menstrual Bleeding
Interventions: Elagolix, Placebo for Estradiol/Norethindrone Acetate, Estradiol/Norethindrone Acetate, Placebo for Elagolix; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 51 Years · Female only
Enrollment: 378 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 103
States / cities: Birmingham, Alabama • Dothan, Alabama • Fairhope, Alabama + 89 more

Conditions: Heavy Menstrual Bleeding, Bleeding Disorder, Von Willebrand Diseases
Interventions: Levonorgestrel Intrauterine System, Norethindrone Acetate; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 10 Years to 24 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 9
States / cities: Palo Alto, California • Aurora, Colorado • Atlanta, Georgia + 5 more

Conditions: Amenorrhea
Interventions: DR-2021a, DR-2021b, DR-2021c, DR-2021d, DR-2021e, Placebo; Drug · Other
Lead sponsor: Duramed Research; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 27
States / cities: Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 22 more

Conditions: Menorrhagia, Heavy Menstrual Bleeding
Interventions: Tranexamic acid tablets, Placebo tablets; Drug
Lead sponsor: Ferring Pharmaceuticals; Industry
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 52
States / cities: Tucson, Arizona • Little Rock, Arkansas • Carmichael, California + 46 more

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Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain

The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels

Mirena Extension Trial

Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief

Effects of Seed Cycling Capsules on Premenstrual Syndrome Symptoms and Menstrual Cycle Length

Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy Menstrual Bleeding

A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).

Minitouch Endometrial Ablation System Treatment for Menorrhagia: An Evaluation of Safety & Effectiveness

A Study to Evaluate Changes in Hair in Adult Participants Taking Oral Oriahnn Capsules With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)

A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test

The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms

Glycemic Profiles And Insulin Delivery Across The Menstrual Cycle In Women With Type 1 Diabetes

Estradiol vs Lysteda in Treatment of Heavy Menstrual Bleeding

Single Session of tACS in a Depressive Episode

Ovarian Follicle Function in Patients With Primary Ovarian Failure

Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding

GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients

Hormonal Influences on Inflammatory Bowel Diseases

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

A Trial to Evaluate DR-2021 in Women With Secondary Amenorrhea

Efficacy and Safety Study of XP12B in Women With Menorrhagia