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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:29 AM EDT

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Showing 289–312 of 751 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mental Health (Depression) Clear all
Recruiting Not applicable Interventional

IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)

NCT06582784
View directory record Official record
Conditions
Depression, Depressive Symptoms, Cancer
Interventions
Behavioral Activation Therapy App, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Recruiting Not applicable Interventional

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

NCT07227337
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Depression, Violence
Interventions
BSHAPE, Control (general wellness)
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
676 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

How Body Awareness Promotes Mental Health During Yoga and Physical Exercise

NCT03553745
View directory record Official record
Conditions
Negative Thoughts, Mild Depression, Stress
Interventions
Gentle Yoga Intervention, Rigorous Yoga Intervention, Physical Exercise Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Mental Health in the Hospital Setting

NCT03777046
View directory record Official record
Conditions
Post Partum Depression
Interventions
Standard of Care (SOC), SOC with Psychology Therapy (CBT)
Behavioral
Lead sponsor
Michelle Lopez
Other
Eligibility
18 Years and older · Female only
Enrollment
545 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Mentor Texting

NCT07380061
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety, Parenting Stress
Interventions
Peer mentor texting, Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

NCT04743466
View directory record Official record
Conditions
Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Electronic Health Record Review
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health

NCT07217561
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety
Interventions
Doula Link
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 20, 2026, 5:29 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care

NCT04356274
View directory record Official record
Conditions
PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
Interventions
Participatory System Dynamics (PSD), Audit and Feedback (AF)
Other
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Withdrawn Not applicable Interventional

Lifestyle MIND- Feasibility of Wait-list Control

NCT06384521
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Serious Mental Illness, Schizophrenia, Major Depression, Bipolar Disorder
Interventions
Lifestyle MIND
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional

Health Promotion in Early Adolescence: Sleep, Activity, and Emotion Regulation

NCT01289197
View directory record Official record
Conditions
Sleep Disorders, Physical Activity, Depression, Anxiety
Interventions
Family Check Up
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 13 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Oct 20, 2026, 5:29 AM EDT
Recruiting Not applicable Interventional

Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain

NCT06978166
View directory record Official record
Conditions
Chronic Pain, Depression, Anxiety
Interventions
Just-In-Time Adaptive Interventions (JITAIs), Wysa for Chronic Pain
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional

Testing a Digital Health Intervention App for Depression and Anxiety

NCT05373329
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Sanvello (app)
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
4,607 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Results available

Factorial Optimization Trial to Test Effects of Coping Intervention Components

NCT05822687
View directory record Official record
Conditions
Anxiety, Depression, Coping Skills, Emotional Problem
Interventions
Education, Reappraisal Coping, Distraction Coping, Relaxation Coping
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
9 Years to 12 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Classification and Assessment of Mental Health Performance Using Schematics

NCT04275908
View directory record Official record
Conditions
Suicide Ideation, Suicidal Intention, Suicide and Depression
Interventions
MHSAFE app
Device
Lead sponsor
Clarigent Health
Industry
Eligibility
8 Years to 23 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yoga for Stress and Mental Health

NCT01652807
View directory record Official record
Conditions
Physiological Stress, Psychological Distress, Depression, Anxiety
Interventions
Hatha Yoga
Behavioral
Lead sponsor
Southern Methodist University
Other
Eligibility
25 Years to 45 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 20, 2026, 5:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ROSE in Sunset Park

NCT04940585
View directory record Official record
Conditions
Post Partum Depression
Interventions
ROSE Program
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Recruiting Phase 2 Interventional

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

NCT05869682
View directory record Official record
Conditions
Advanced Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Carcinoma, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
Interventions
Bright White Light Therapy, Combination Drug Therapy, Electronic Health Record Review, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Drug · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
60 Years and older · Male only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional

Electronic Communication Augmented Mental Health Care

NCT03925038
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders, Bipolar Affective Disorder
Interventions
Augmented Care: Electronic Media Dashboard, Treatment as Usual
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 100 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 20, 2026, 5:29 AM EDT
Not yet recruiting Not applicable Interventional

Improving Perinatal Mental Health Through a Collaborative, Community Health Worker and Social Worker Intervention

NCT07880457
View directory record Official record
Conditions
Perinatal Anxiety, Perinatal Depression
Interventions
Patient Navigation (PN), Problem Solving Therapy (PST)
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Phase 2 Interventional

Stabilizing Behavioral Rhythms to Improve Mental Health

NCT03152864
View directory record Official record
Conditions
Depressive Symptoms, Anxiety Symptoms, Sleep Symptoms
Interventions
Full Package
Behavioral
Lead sponsor
HealthRhythms, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Mood in Assisted Living Settings

NCT01763216
View directory record Official record
Conditions
Depressive Symptoms, Clinical Depression
Interventions
Road Tour, Boatload of Crosswords
Other
Lead sponsor
Marianne Smith
Other
Eligibility
55 Years and older
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
32
States / cities
Amana, Iowa • Bettendorf, Iowa • Carlisle, Iowa + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Phase 3 Interventional

Supporting the Well Being of Families of Young Children With Autism Spectrum Disorders

NCT01021384
View directory record Official record
Conditions
Maternal Depression
Interventions
Problem Solving Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Female only
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Oct 20, 2026, 5:29 AM EDT
Terminated Not applicable Interventional

Effect of Sleep Quality on Hematopoietic Cell Transplant Patient Outcomes

NCT04271930
View directory record Official record
Conditions
Sleep, Multiple Myeloma
Interventions
Mindfulness Awareness Practices for Insomnia, Sleep Health Information
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 20, 2026, 5:29 AM EDT
Completed Phase 4 Interventional Results available

The BIomarker Guided (BIG) Study for Depression

NCT04181736
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Guanfacine Tablets
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 69 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 20, 2026, 5:29 AM EDT