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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:22 PM EDT

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Showing 409–432 of 751 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mental Health (Depression) Clear all
Recruiting Not applicable Interventional

Teen Recovery Through Inspiration, Support, and Empowerment

NCT07170657
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
Interventions
Peer Support Services Recovery
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Audio-based Mental Health Intervention Study

NCT05555745
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Audio-based behavioral activation intervention, Audio-based self-monitoring intervention
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rhythmically Entrained Exercise in Community-Dwelling Older Adults

NCT05462977
View directory record Official record
Conditions
Exercise, Gait, Cognitive Decline, Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Mild Cognitive Impairment, Respite Care, Mental Health, Depression, Music Therapy, Psychosocial Intervention, Cognition, Geriatric Assessment, Cognitive Dysfunction, Cognitive Aging, Outcome Assessment, Health Care, Balance, Fall, Walking, Affect, Physical Exertion, Memory Deficit, Memory Disorders, Memory Impairment, Neuropsychological Tests, Executive Function, Middle Aged, Healthy Aging, Elderly
Interventions
Group exercise program
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
55 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Maternal Mental Health and Wellbeing in Neonatal Intensive Care

NCT03942627
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Post-traumatic Stress Symptoms
Interventions
Mindfulness Program, Infant Health Education Program
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 20, 2026, 2:22 PM EDT
Recruiting Not applicable Interventional

Collaborative Care Model for Perinatal Wellness Support Services - Population-Level Equity-Centered Systems Change

NCT06849869
View directory record Official record
Conditions
Perinatal Mental Health
Interventions
COMPASS+
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
14,820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health

NCT04001088
View directory record Official record
Conditions
Menopause
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Lallemand Health Solutions
Industry
Eligibility
40 Years to 59 Years · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
5
States / cities
Lake Worth, Florida • Port Saint Lucie, Florida • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional

Baby2Home (B2H) Mobile Health Application

NCT05595486
View directory record Official record
Conditions
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions
Baby2Home Mobile Application
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Withdrawn Phase 4 Interventional

EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders

NCT04123483
View directory record Official record
Conditions
Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Premenstrual Tension, Menstrual Related Mood Disorder
Interventions
EnBrace HR Softgel
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 52 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 20, 2026, 2:22 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Cereset Research for Performance Improvement in a Hospital Nursing Unit

NCT06378554
View directory record Official record
Conditions
Health Personnel, Stress, Anxiety, Insomnia, Depression
Interventions
Cereset Research
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional

Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

NCT06665620
View directory record Official record
Conditions
Suicide, Mental Health Disorder, Anhedonia
Interventions
ViraBrite nudges
Behavioral
Lead sponsor
Ksana Health
Industry
Eligibility
13 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Terminated Not applicable Interventional

Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3)

NCT03609450
View directory record Official record
Conditions
Depression, Anxiety Disorders, Stress Related Disorder, Adjustment Disorders, Chronic Illness
Interventions
Mindfulness Training for Primary Care, Low-Dose Comparator
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being

NCT07809958
View directory record Official record
Conditions
Interoceptive Awareness, Interoception, Alexithymia, Anxiety, Depression Disorders
Interventions
Heart rate feedback from smartwatch
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SSIs for Mental Health and Loneliness

NCT05687162
View directory record Official record
Conditions
Loneliness, Mental Health Issue, Distress, Emotional, Depression, Anxiety, Stress
Interventions
Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program, The Blu Surfer program: a popular online content-based intervention for psychological distress, The Action Brings Change (ABC) Program (TEAM Lab version), Online help-seeking as usual, The Lonely Blu Surfer program: a popular online content-based intervention for loneliness, Overcoming loneliness SSI 8-minute version
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
16 Years and older
Enrollment
4,370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional

Media Project and Health Study - Spanish Version

NCT04862624
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Catalina Story-Based Web-App, Attention Control Web-App
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional

Health Promotion in Early Adolescence: Sleep, Activity, and Emotion Regulation

NCT01289197
View directory record Official record
Conditions
Sleep Disorders, Physical Activity, Depression, Anxiety
Interventions
Family Check Up
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 13 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Oct 20, 2026, 2:22 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

COVID-19-Related Health and Practices Among Dental Hygienists

NCT04542915
View directory record Official record
Conditions
SARS-CoV Infection, Anxiety, Depression, Occupational Problems, Severe Acute Respiratory Syndrome, Coronavirus Infection
Interventions
No intervention
Other
Lead sponsor
American Dental Association
Other
Eligibility
18 Years and older
Enrollment
6,976 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 20, 2026, 2:22 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Just-in-Time Training for Youth Mentors

NCT07129070
View directory record Official record
Conditions
Mental Health Issue, Depression, Anxiety
Interventions
Interpersonal Psychotherapy-Adolescent Skills Training via Just-In-Time Training (JITT) implementation strategy, Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) implemented via usual training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Recruiting Not applicable Interventional

Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

NCT07118722
View directory record Official record
Conditions
Chronic Pain, Depression
Interventions
Quiet Focus, Health Enhancement Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 120 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inner Engineering Yoga Program on Short and Long Term Health Effects (ISHA-Impact): A Longitudinal Study

NCT04189146
View directory record Official record
Conditions
Mediation, Mood, Stress, Habits, Nicotine, Alcohol Consumption, Pain Intensity, Sleep, Mindfulness, Emotions, Anxiety, Depression
Interventions
Inner Engineering Intervention
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
618 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 20, 2026, 2:22 PM EDT
Active, not recruiting Not applicable Interventional

Positive Minds Strong Joints for Knee Osteoarthritis

NCT06493903
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Positive Minds, Strong Joints
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
50 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health

NCT05975008
View directory record Official record
Conditions
Depression
Interventions
RECLAIM - Reconnecting to Civilian Life using Activities that Improve Mindfulness
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 44 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Phase 3 Interventional

Supporting the Well Being of Families of Young Children With Autism Spectrum Disorders

NCT01021384
View directory record Official record
Conditions
Maternal Depression
Interventions
Problem Solving Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Female only
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Oct 20, 2026, 2:22 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 20, 2026, 2:22 PM EDT
Completed Phase 4 Interventional

Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.

NCT00208715
View directory record Official record
Conditions
Major Depression, Mental Health
Interventions
Provigil
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
4
States / cities
Stanford, California • Atlanta, Georgia • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2013 · Synced Oct 20, 2026, 2:22 PM EDT